日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

GSDME-IL-18 pyroptotic axis prevents myosteatosis by expanding tissue-resident macrophages to promote muscle regeneration

GSDME-IL-18 细胞焦亡轴通过扩增组织驻留巨噬细胞来促进肌肉再生，从而预防肌脂肪变性

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI198076
Cao, Qi; Liu, Jian; Huang, Gang; Wang, Su-Yuan; Lu, Guo-Dong; Huang, Yong; Chen, Yi-Ting; Zhang, Zhen; Fu, Jiang-Tao; Sun, Si-Jia; Chen, Xiao-Fei; Zhuang, Chunlin; Sheng, Chunquan; Shen, Fu-Ming; Li, Dong-Jie; Wang, Pei
巨噬细胞
表观遗传
GSDME
巨噬细胞
焦亡
细胞生物学
IL-18
免疫/内分泌
发表日期：2026
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Synthetic Strategies and Biological Diversity of Biflavonoids: Current Status and Perspective

双黄酮的合成策略和生物多样性：现状与展望

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules31060925
Zhang, Yu; Chai, Yue; Wu, Jiabin; Wang, Shuyu; Shi, Jinxin; Wei, Minzhen; Liu, Runhui; Zhuang, Chunlin
发表日期：2026
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Graph neural networks driven acceleration in drug discovery

图神经网络驱动药物发现加速

期刊:Acta Pharmaceutica Sinica B
影响因子:14.6
doi:10.1016/j.apsb.2025.10.011
Wang, Rui; Zhuang, Chunlin
发表日期：2025
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Chemical knockdown of Keap1 and homoPROTAC-ing allergic rhinitis.

Keap1 的化学敲除和 homoPROTAC 引起的过敏性鼻炎

期刊:Acta Pharmaceutica Sinica B
影响因子:14.6
doi:10.1016/j.apsb.2025.05.025
Yan Jianyu, Wang Tianyu, Yu Ruizhi, Xu Lijuan, Shao Hongming, Li Tengfei, Wang Zhe, Cha Xudong, Miao Zhenyuan, Xing Chengguo, Xu Ke, Liu Huanhai, Zhuang Chunlin
炎症/感染
鼻炎
炎症
发表日期：2025
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Mixed Lineage Kinase Domain-Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities

混合谱系激酶结构域样蛋白（MLKL）：从机制到治疗机遇

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202509277
Xu, Lijuan; Zhuang, Chunlin
信号转导
MLKL
发表日期：2025
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Design of anti-depressant phosphodiester amino acidic Keap1-Nrf2 protein-protein interaction inhibitors

抗抑郁磷酸二酯氨基酸Keap1-Nrf2蛋白-蛋白相互作用抑制剂的设计

期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2025.103620
Sun, Yi; Wang, Jue; Ding, Wenxin; Qin, Qingqing; Wang, Rui; Yu, Ruizhi; Yan, Jianyu; Hou, Ruilin; Liu, Guodong; Cai, Xiangming; Qu, Zhuo; Zhang, Wannian; Yu, Jianqiang; Xing, Chengguo; Zhuang, Chunlin
神经科学
发表日期：2025
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Pharmacokinetic, Tissue Distribution, Metabolite, and Toxicity Evaluation of the Matrine Derivative, (6aS, 10S, 11aR, 11bR, 11cS)-10-Methylaminododecahydro-3a, 7a-Diaza-benzo (de) Anthracene-8-thione

苦参碱衍生物(6aS, 10S, 11aR, 11bR, 11cS)-10-甲基氨基十二氢-3a,7a-二氮杂苯并(de)蒽-8-硫酮的药代动力学、组织分布、代谢物和毒性评价

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules29020297
Li, Liuyan; Lu, Fangfang; Ding, Shuqin; Wang, Xiaoying; Wang, Weibiao; Zhang, Wannian; Xu, Weiheng; Zhuang, Chunlin; Miao, Zhenyuan; Ma, Xueqin
代谢
毒理研究
发表日期：2024
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Structure-Activity Relationship Study of (E)-3-(6-Fluoro-1H-indol-3-Yl)-2-methyl-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one (FC116) Against Metastatic Colorectal Cancers Resistant to Oxaliplatin.

（E）-3-（6-氟-1H-吲哚-3-基）-2-甲基-1-（3,4,5-三甲氧基苯基）丙-2-烯-1-酮（FC116）对奥沙利铂耐药转移性结直肠癌的构效关系研究

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.4c00024
Wang Shuyu, Ge Qinghua, Cong Hui, Zhang Wannian, Liu Huanhai, Qu Zhuo, Chen Haihu, Zhuang Chunlin
肿瘤
肠癌
发表日期：2024
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Dietary Phytochemicals as Potential Chemopreventive Agents against Tobacco-Induced Lung Carcinogenesis

膳食植物化学物质作为潜在的抗烟草诱发肺癌的化学预防剂

期刊:Nutrients
影响因子:5
doi:10.3390/nu15030491
Ding, Yan; Hou, Ruilin; Yu, Jianqiang; Xing, Chengguo; Zhuang, Chunlin; Qu, Zhuo
肺癌
肿瘤
肿瘤免疫
发表日期：2023
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Improving the positional adaptability: structure-based design of biphenyl-substituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

提高位置适应性：基于结构的联苯取代二芳基三嗪类化合物设计作为新型非核苷类HIV-1逆转录酶抑制剂

期刊:Acta Pharmaceutica Sinica B
影响因子:14.6
doi:10.1016/j.apsb.2019.09.007
Jin, Kaijun; Liu, Minjie; Zhuang, Chunlin; De Clercq, Erik; Pannecouque, Christophe; Meng, Ge; Chen, Fener
HIV
微生物学
发表日期：2020
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