CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and target genes.
利用 CRISPR/Cas9 介导的大西洋鲑鱼 (Salmo salar L.) 中 elovl2 的消融抑制了多不饱和脂肪酸的延长,并诱导了 Srebp-1 和靶基因的表达
期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-019-43862-8
Datsomor Alex K, Zic Nikola, Li Keshuai, Olsen Rolf E, Jin Yang, Vik Jon Olav, Edvardsen Rolf B, Grammes Fabian, Wargelius Anna, Winge Per