Zifang相关文献与解析，生知库 | 链接生命科学的每一步

E3 ubiquitin ligase NEDD4 inhibits PEDV infection through ubiquitination and degradation of the viral primase NSP8.

E3 泛素连接酶 NEDD4 通过泛素化和降解病毒引物酶 NSP8 来抑制 PEDV 感染。

Guo Xuyang, Zhao Xiaojing, He Jianyu, Lu Yuchen, Jin Sijia, Ma Zhiqian, Li Zhiwei, Zheng Zifang, Li Yang, Feng Yingtong, Xu Lele, Liu Xiao, Zhang Jianwu, Wei Zhanyong, Zheng Haixue, Xiao Shuqi

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Elucidating EGCG' s targets in nasopharyngeal carcinoma through combined cell-based assays and transcriptomic sequencing

通过结合细胞实验和转录组测序，阐明EGCG在鼻咽癌中的靶点。

期刊:Discover Oncology

影响因子:2.9

doi:10.1007/s12672-026-04657-2

Yang, Yuhang; Xuan, Guangxu; Feng, Zhang; Deng, Ming; Liu, Fangxian; Liu, Qianghe; Wang, Wenhua; Li, Zifang; Zuo, Dongzhi; Li, Zhenya; Wei, Congbao; Luo, Wenqi; Li, Fei; Ma, Ning; He, Feng; Murata, Mariko

Injecting OVD temporarily seal the edge of the retinectomy to prevent subretinal perfluorocarbon liquid droplets retention and retinal slippage during fluid-air exchange

注射粘弹剂可暂时封闭视网膜切除边缘，以防止视网膜下全氟碳液滴滞留和液气交换过程中视网膜滑脱。

期刊:International Journal of Retina and Vitreous

影响因子:2.4

doi:10.1186/s40942-026-00828-z

He, Zifang; Guo, Yinong; Yilihaer, Yilinuer; Liu, Suyu; Tang, Yifei; Xie, Lv; Zhang, Ye; Liu, Yajun; Xie, Zhenggao

发表日期：2026

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High-frequency, low-energy organic event-based sensors for closed-loop neurostimulation

用于闭环神经刺激的高频、低能耗有机事件传感器

期刊:

影响因子:

doi:10.1038/s44460-025-00007-x

Yang, Chi-Yuan; Zhao, Zifang; Wu, Han-Yan; Gao, Dace; Huang, Jun-Da; Ji, Junpeng; Xiong, Miao; Liu, Tiefeng; Harikesh, Padinhare C; Marks, Adam; Wang, Xin-Yi; Massetti, Matteo; Shao, Shan; Pei, Jian; McCulloch, Iain; Berggren, Magnus; Tu, Deyu; Gelinas, Jennifer; Khodagholy, Dion; Fabiano, Simone

发表日期：2026

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Closed-loop electrical stimulation prevents focal epilepsy progression and long-term memory impairment

闭环电刺激可预防局灶性癫痫进展和长期记忆损伤。

期刊:Nature Neuroscience

影响因子:20

doi:10.1038/s41593-025-01988-1

Ferrero, Jose J; Hassan, Ahnaf R; Yu, Zelin; Zhao, Zifang; Ma, Liang; Wu, Cynthia; Shao, Shan; Kawano, Takeshi; Engel, Judah; Doyle, Werner; Devinsky, Orrin; Khodagholy, Dion; Gelinas, Jennifer N

Spatial control of doping in conducting polymers enables complementary, conformable, implantable internal ion-gated organic electrochemical transistors

通过对导电聚合物中掺杂进行空间控制，可以实现互补的、可变形的、可植入的内部离子门控有机电化学晶体管。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-024-55284-w

Wisniewski, Duncan J; Ma, Liang; Rauhala, Onni J; Cea, Claudia; Zhao, Zifang; Ranschaert, Alexander; Gelinas, Jennifer N; Khodagholy, Dion

发表日期：2025

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Methionine-driven YTHDF1 expression facilitates bladder cancer progression by attenuating RIG-I-modulated immune responses and enhancing the eIF5B-PD-L1 axis

甲硫氨酸驱动的YTHDF1表达通过减弱RIG-I调节的免疫反应和增强eIF5B-PD-L1轴促进膀胱癌进展。

期刊:Cell Death and Differentiation

影响因子:15.4

doi:10.1038/s41418-024-01434-y

Yu, Anze; Fu, Liangmin; Jing, Lanyu; Wang, Yinghan; Ma, Zifang; Zhou, Xinwei; Yang, Rui; Liu, Jinhui; Hu, Jiao; Feng, Wei; Yang, Taowei; Chen, Zhenhua; Zu, Xiongbing; Chen, Wei; Chen, Junxing; Luo, Junhang

GLUL mediates FOXO3 O-GlcNAcylation to regulate the osteogenic differentiation of BMSCs and senile osteoporosis

GLUL介导FOXO3 O-GlcNAc糖基化，从而调节BMSCs的成骨分化和老年性骨质疏松症。

期刊:Cell Death and Differentiation

影响因子:15.4

doi:10.1038/s41418-025-01543-2

Zhang, Lu; Qi, Bao; Li, Yanpeng; Liang, Xiao; Zhang, Zifang; Yang, Tao; Jia, Shu; Gao, Xu; Chen, Shang; Jiao, Guangjun; Li, Yangyang; Zhou, Hongming; Chen, Yunzhen; Li, Yanming; Zhang, Bin; Li, Gang; Meng, Chunyang

Inhibition of HMGA2 binding to AT-rich DNA by its negatively charged C-terminus

HMGA2 的 C 端带负电荷，抑制其与富含 AT 的 DNA 结合

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkaf035

Su, Linjia; Deng, Zifang; Santos-Fernandez, Miguel; Jeanne Dit Fouque, Kevin; Chapagain, Prem P; Chambers, Jeremy W; Fernandez-Lima, Francisco; Leng, Fenfei

发表日期：2025

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A tale of dual role: HECT‑type E3 ubiquitin ligase mechanisms in liver diseases (Review)

双重作用的故事：HECT型E3泛素连接酶在肝脏疾病中的作用机制（综述）

E3 ubiquitin ligase NEDD4 inhibits PEDV infection through ubiquitination and degradation of the viral primase NSP8.

E3 泛素连接酶 NEDD4 通过泛素化和降解病毒引物酶 NSP8 来抑制 PEDV 感染。

Elucidating EGCG' s targets in nasopharyngeal carcinoma through combined cell-based assays and transcriptomic sequencing

通过结合细胞实验和转录组测序，阐明EGCG在鼻咽癌中的靶点。

Injecting OVD temporarily seal the edge of the retinectomy to prevent subretinal perfluorocarbon liquid droplets retention and retinal slippage during fluid-air exchange

注射粘弹剂可暂时封闭视网膜切除边缘，以防止视网膜下全氟碳液滴滞留和液气交换过程中视网膜滑脱。

High-frequency, low-energy organic event-based sensors for closed-loop neurostimulation

用于闭环神经刺激的高频、低能耗有机事件传感器

Closed-loop electrical stimulation prevents focal epilepsy progression and long-term memory impairment

闭环电刺激可预防局灶性癫痫进展和长期记忆损伤。

Spatial control of doping in conducting polymers enables complementary, conformable, implantable internal ion-gated organic electrochemical transistors

通过对导电聚合物中掺杂进行空间控制，可以实现互补的、可变形的、可植入的内部离子门控有机电化学晶体管。

Methionine-driven YTHDF1 expression facilitates bladder cancer progression by attenuating RIG-I-modulated immune responses and enhancing the eIF5B-PD-L1 axis

甲硫氨酸驱动的YTHDF1表达通过减弱RIG-I调节的免疫反应和增强eIF5B-PD-L1轴促进膀胱癌进展。

GLUL mediates FOXO3 O-GlcNAcylation to regulate the osteogenic differentiation of BMSCs and senile osteoporosis

GLUL介导FOXO3 O-GlcNAc糖基化，从而调节BMSCs的成骨分化和老年性骨质疏松症。

Inhibition of HMGA2 binding to AT-rich DNA by its negatively charged C-terminus

HMGA2 的 C 端带负电荷，抑制其与富含 AT 的 DNA 结合