日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Point of view: Challenges in implementation of new immunotherapies for Alzheimer's disease

观点:阿尔茨海默病新型免疫疗法实施面临的挑战

Aye, Sandar; Johansson, Gunilla; Hock, Christoph; Lannfelt, Lars; Sims, John R; Blennow, Kaj; Frederiksen, Kristian S; Graff, Caroline; Molinuevo, José Luis; Scheltens, Philip; Palmqvist, Sebastian; Schöll, Michael; Wimo, Anders; Kivipelto, Miia; Handels, Ron; Frölich, Lutz; Zilka, Norbert; Tolar, Martin; Johannsen, Peter; Jönsson, Linus; Winblad, Bengt

Identification of a presymptomatic and early disease signature for amyotrophic lateral sclerosis (ALS): protocol of the premodiALS study

肌萎缩侧索硬化症 (ALS) 症状前和早期疾病特征的识别:premodiALS 研究方案

Tzeplaeff, Laura; Galhoz, Ana; Meijs, Clara; Caldi Gomes, Lucas; Kovac, Andrej; Menzel, Amrei; Değirmenci, Hatice; Alaamel, Abir; Kaya, Hüseyin Can; Çelik, Ali Günalp; Dinçer, Sine; Korucuk, Meltem; Karaüzüm, Sibel Berker; Bayraktar, Elif; Çiftçi, Vildan; Bilge, Uğur; Koç, Filiz; Demleitner, Antonia F; Buchberger, Anne; von Heynitz, Ricarda; Gmeiner, Vincent; Knellwolf, Christina; Mouzouri, Mohammed; Wuu, Joanne; Başak, A Nazli; Andersen, Peter Munch; Kohlmayer, Florian; Ashton, Nicholas J; Kuban, Wojciech; Lenz, Christof; Rogers, Mary-Louise; Zilka, Norbert; Corcia, Philippe; Lerner, Yossef; Weber, Markus; Turcanova Koprusakova, Monika; Uysal, Hilmi; Benatar, Michael; Menden, Michael P; Lingor, Paul

Micronutrient dynamics and deficiency risk across pregnancy and postpartum in a Slovak cohort

斯洛伐克人群中孕期和产后微量营养素动态变化及缺乏风险

Kristufkova, Alexandra; Basheer, Neha; Koprdova, Katarina; Lieskovsky, Matus; Fresser, Michal; Zilka, Norbert

Identification of a presymptomatic and early disease signature for Amyotrophic Lateral Sclerosis (ALS): protocol of the premodiALS study

肌萎缩侧索硬化症 (ALS) 症状前和早期疾病特征的识别:premodiALS 研究方案

Tzeplaeff, Laura; Galhoz, Ana; Meijs, Clara; Gomes, Lucas Caldi; Kovac, Andrej; Menzel, Amrei; Değirmenci, Hatice; Alaamel, Abir; Kaya, Hüseyin Can; Çelik, Ali Günalp; Dinçer, Sine; Korucuk, Meltem; Karaüzüm, Sibel Berker; Bayraktar, Elif; Çiftçi, Vildan; Bilge, Uğur; Koç, Filiz; Demleitner, Antonia F; Buchberger, Anne; von Heynitz, Ricarda; Gmeiner, Vincent; Knellwolf, Christina; Mouzouri, Mohammed; Wuu, Joanne; Başak, A Nazlı; Andersen, Peter Munch; Kohlmayer, Florian; Ashton, Nicholas J; Kuban, Wojciech; Lenz, Christof; Rogers, Mary-Louise; Zilka, Norbert; Corcia, Philippe; Lerner, Yossef; Weber, Markus; Koprusakova, Monika Turcanova; Uysal, Hilmi; Benatar, Michael; Menden, Michael P; Lingor, Paul

Efficacy assessment of an active tau immunotherapy in Alzheimer's disease patients with amyloid and tau pathology: a post hoc analysis of the "ADAMANT" randomised, placebo-controlled, double-blind, multi-centre, phase 2 clinical trial

对伴有淀粉样蛋白和tau蛋白病理的阿尔茨海默病患者进行活性tau免疫疗法疗效评估:一项“ADAMANT”随机、安慰剂对照、双盲、多中心II期临床试验的事后分析

Cullen, Nicholas C; Novak, Petr; Tosun, Duygu; Kovacech, Branislav; Hanes, Jozef; Kontsekova, Eva; Fresser, Michal; Ropele, Stefan; Feldman, Howard H; Schmidt, Reinhold; Winblad, Bengt; Zilka, Norbert

Evaluating language models for mathematics through interactions

通过交互评估数学语言模型

Collins, Katherine M; Jiang, Albert Q; Frieder, Simon; Wong, Lionel; Zilka, Miri; Bhatt, Umang; Lukasiewicz, Thomas; Wu, Yuhuai; Tenenbaum, Joshua B; Hart, William; Gowers, Timothy; Li, Wenda; Weller, Adrian; Jamnik, Mateja

Post hoc analysis of ADAMANT, a phase 2 clinical trial of active tau immunotherapy with AADvac1 in patients with Alzheimer's disease, positive for plasma p-tau217

对 ADAMANT(一项针对血浆 p-tau217 阳性阿尔茨海默病患者的活性 tau 免疫疗法 AADvac1 的 2 期临床试验)的事后分析

Kovacech, Branislav; Cullen, Nicholas C; Novak, Petr; Hanes, Jozef; Kontsekova, Eva; Katina, Stanislav; Parrak, Vojtech; Fresser, Michal; Vanbrabant, Jeroen; Feldman, Howard H; Winblad, Bengt; Stoops, Erik; Vanmechelen, Eugeen; Zilka, Norbert

Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models

塑造阿尔茨海默病疾病修饰药物临床前开发的未来:tau蛋白传播模型的系统性综述

Basheer, Neha; Buee, Luc; Brion, Jean-Pierre; Smolek, Tomas; Muhammadi, Muhammad Khalid; Hritz, Jozef; Hromadka, Tomas; Dewachter, Ilse; Wegmann, Susanne; Landrieu, Isabelle; Novak, Petr; Mudher, Amritpal; Zilka, Norbert

TLR4-mediated chronic neuroinflammation has no effect on tangle pathology in a tauopathy mouse model

TLR4 介导的慢性神经炎症对 tau 蛋白病小鼠模型中的缠结病理没有影响

Neha Basheer #, Muhammad Khalid Muhammadi #, Carlos Leandro Freites, Martin Avila, Miraj Ud Din Momand, Natalia Hryntsova, Tomas Smolek, Stanislav Katina, Norbert Zilka

On the utility of cerebrospinal fluid biomarkers in canine neurological disorders

脑脊液生物标志物在犬神经系统疾病中的应用

Smolek, Tomas; Vince-Kazmerova, Zuzana; Hanes, Jozef; Stevens, Eva; Palus, Viktor; Hajek, Ivo; Katina, Stanislav; Novak, Petr; Zilka, Norbert