Pathway coessentiality mapping reveals complex II is required for de novo purine biosynthesis in acute myeloid leukaemia
通路共必需性分析揭示复合物 II 是急性髓系白血病中嘌呤从头合成所必需的
期刊:Nature Metabolism
影响因子:20.8
doi:10.1038/s42255-025-01410-x
Stewart, Amy E; Zachman, Derek K; Castellano-Escuder, Pol; Kelly, Lois M; Zolyomi, Ben; Aiduk, Michael D I; Delaney, Christopher D; Lock, Ian C; Bosc, Claudie; Bradley, John; Killarney, Shane T; Stuart, J Darren; Grimsrud, Paul A; Ilkayeva, Olga R; Newgard, Christopher B; Chandel, Navdeep S; Puissant, Alexandre; Wood, Kris C; Hirschey, Matthew D
