日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Sulfatides are endogenous ligands for the TLR4-MD-2 complex

硫脂是TLR4-MD-2复合物的内源性配体。

Su, Lijing; Athamna, Muhammad; Wang, Ying; Wang, Junmei; Freudenberg, Marina; Yue, Tao; Wang, Jianhui; Moresco, Eva Marie Y; He, Haoming; Zor, Tsaffrir; Beutler, Bruce

Exogenous ceramide-1-phosphate (C1P) and phospho-ceramide analogue-1 (PCERA-1) regulate key macrophage activities via distinct receptors

外源性神经酰胺-1-磷酸(C1P)和磷酸神经酰胺类似物-1(PCERA-1)通过不同的受体调节巨噬细胞的关键活性。

Katz, Sebastián; Ernst, Orna; Avni, Dorit; Athamna, Muhammad; Philosoph, Amir; Arana, Lide; Ouro, Alberto; Hoeferlin, L Alexis; Meijler, Michael M; Chalfant, Charles E; Gómez-Muñoz, Antonio; Zor, Tsaffrir

A ceramide analog inhibits cPLA(2) activity and consequent PGE(2) formation in LPS-stimulated macrophages.

神经酰胺类似物抑制 LPS 刺激的巨噬细胞中 cPLA(2) 活性和随之而来的 PGE(2) 形成

Goldsmith Meir, Daka Ala, Lamour Nadia F, Mashiach Roi, Glucksam Yifat, Meijler Michael M, Chalfant Charles E, Zor Tsaffrir

The ceramide-1-phosphate analogue PCERA-1 modulates tumour necrosis factor-alpha and interleukin-10 production in macrophages via the cAMP-PKA-CREB pathway in a GTP-dependent manner

神经酰胺-1-磷酸类似物PCERA-1通过GTP依赖性的cAMP-PKA-CREB通路调节巨噬细胞中肿瘤坏死因子-α和白细胞介素-10的产生。

Avni, Dorit; Philosoph, Amir; Meijler, Michael M; Zor, Tsaffrir

A ceramide-1-phosphate analogue, PCERA-1, simultaneously suppresses tumour necrosis factor-alpha and induces interleukin-10 production in activated macrophages

神经酰胺-1-磷酸类似物 PCERA-1 可同时抑制活化巨噬细胞中的肿瘤坏死因子-α 并诱导白细胞介素-10 的产生。

Goldsmith, Meir; Avni, Dorit; Levy-Rimler, Galit; Mashiach, Roi; Ernst, Orna; Levi, Maya; Webb, Bill; Meijler, Michael M; Gray, Nathanael S; Rosen, Hugh; Zor, Tsaffrir