Zou Xinle相关文献与解析，生知库 | 链接生命科学的每一步

Shi, Bingbo; Li, Jiajun; Wang, Xiaomin; Liu, Dong; Xiang, Jinzhu; Wang, Hanning; Xu, Changjiang; Zou, Xinle; Wang, Zhuangfei; Huang, Tao; Min, Qiankun; Wang, Kaipeng; Yang, Yihang; Li, Junyang; Wang, Bo; Zhao, Chengchen; Pei, Duanqing

细胞生物学

发育与干细胞

干细胞

发表日期：2026

文献求助收藏

Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies.

利用二价纳米抗体靶向募集 NEDD4-2 来抑制离子通道。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-67068-x

Darko-Boateng Arden, Afriyie Emmanuel, Morgenstern Travis J, Shanmugam Sri Karthika, Zou Xinle, Laloudakis Yianni D, Choudhury Papiya, Desai Meera, Kass Robert S, Vallese Francesca, Clarke Oliver B, Colecraft Henry M

NEDD4

发表日期：2025

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Decoding polyubiquitin regulation of K(V)7. 1 (KCNQ1) surface expression with engineered linkage-selective deubiquitinases.

利用工程化的连接选择性去泛素化酶解码多泛素对 K(V)7.1 (KCNQ1) 表面表达的调控

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-60893-0

Shanmugam Sri Karthika, Kanner Scott A, Zou Xinle, Amarh Enoch, Choudhury Papiya, Soni Rajesh, Kass Robert S, Colecraft Henry M

Two small-molecule activators share similar effector sites in the KCNQ1 channel pore but have distinct effects on voltage sensor movements

两种小分子激活剂在KCNQ1通道孔中具有相似的效应位点，但对电压传感器的运动却产生不同的影响。

期刊:Frontiers in Physiology

影响因子:3.4

doi:10.3389/fphys.2022.903050

Chen, Lei; Peng, Gary; Comollo, Thomas W; Zou, Xinle; Sampson, Kevin J; Larsson, H Peter; Kass, Robert S

发表日期：2022

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Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels

药物治疗KCNQ1/KCNE1通道特定长QT间期变异体

期刊:Frontiers in Physiology

影响因子:3.4

doi:10.3389/fphys.2022.902224

Zou, Xinle; Wu, Xiaoan; Sampson, Kevin J; Colecraft, Henry M; Larsson, H Peter; Kass, Robert S

发表日期：2022

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Exploring mutation specific beta blocker pharmacology of the pathogenic late sodium channel current from patient-specific pluripotent stem cell myocytes derived from long QT syndrome mutation carriers

探索源自长QT综合征突变携带者的患者特异性多能干细胞肌细胞的致病性晚期钠通道电流的突变特异性β受体阻滞剂药理学

期刊:Channels

影响因子:3.2

doi:10.1080/19336950.2022.2106025

Comollo, Thomas W; Zou, Xinle; Zhang, Chuangeng; Kesters, Divya; Hof, Thomas; Sampson, Kevin J; Kass, Robert S

Generating high-quality porcine iPSCs with the new medium cocktail LACID

利用新型培养基混合物 LACID 生成高质量的猪诱导多能干细胞

Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies.

利用二价纳米抗体靶向募集 NEDD4-2 来抑制离子通道。

Decoding polyubiquitin regulation of K(V)7. 1 (KCNQ1) surface expression with engineered linkage-selective deubiquitinases.

利用工程化的连接选择性去泛素化酶解码多泛素对 K(V)7.1 (KCNQ1) 表面表达的调控

Two small-molecule activators share similar effector sites in the KCNQ1 channel pore but have distinct effects on voltage sensor movements

两种小分子激活剂在KCNQ1通道孔中具有相似的效应位点，但对电压传感器的运动却产生不同的影响。

Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels

药物治疗KCNQ1/KCNE1通道特定长QT间期变异体

Exploring mutation specific beta blocker pharmacology of the pathogenic late sodium channel current from patient-specific pluripotent stem cell myocytes derived from long QT syndrome mutation carriers

探索源自长QT综合征突变携带者的患者特异性多能干细胞肌细胞的致病性晚期钠通道电流的突变特异性β受体阻滞剂药理学