日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nighttime safety of daridorexant: Evaluation of responsiveness to an external noise stimulus, postural stability, walking, and cognitive function

达里多雷生夜间安全性:对外部噪声刺激的反应性、姿势稳定性、行走能力和认知功能的评估

Magliocca, Massimo; Koopmans, Ingrid; Vaillant, Cedric; Lemoine, Vincent; Zuiker, Rob; Dingemanse, Jasper; Muehlan, Clemens

Targeting the MEK1/2 pathway to combat Staphylococcus aureus infection and inflammation in cystic fibrosis

靶向MEK1/2通路以对抗金黄色葡萄球菌感染和囊性纤维化炎症

Zuiker, Eryn; Serpa, Gregory; De, Mithu; Liu, Yiwei; Wozniak, Daniel J; Gowdy, Kymberly M; Charron, Jean; Birket, Susan E; Kiedrowski, Megan R; Hemann, Emily A; Long, Matthew E

Clonazepam repurposing in ARID1B patients through conventional RCT and N-of-1 trials: an experimental strategy for orphan disease development

通过常规随机对照试验和单例试验将氯硝西泮重新用于 ARID1B 患者:一种罕见病研发的实验策略

van der Sluijs, Pleuntje J; Safai Pour, Koshar; Berends, Cécile L; Kruizinga, Matthijs D; Müller, Annelieke R; van Eeghen, Agnies M; Rodríguez-Girondo, Mar; Juachon, Maria J; Steenbeek, Duco; Cohen, Adam F; Zuiker, Rob G J A; Santen, Gijs W E

Safety, Pharmacokinetics, and Pharmacodynamics of a 6-h N,N-Dimethyltryptamine (DMT) Infusion in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled Trial.

在健康志愿者中进行 6 小时 N,N-二甲基色胺 (DMT) 输注的安全性、药代动力学和药效学研究:一项随机、双盲、安慰剂对照试验

van der Heijden Katelijne V, Zuiker Rob G J A, Otto Marije E, Bryan Christopher S, Stewart Nancy, Stillwell Christopher, De Kam Marieke L, van Leuken Marloes B, van Gerven Joop M A, Jacobs Gabriel E

MEK1/2 inhibition decreases pro-inflammatory responses in macrophages from people with cystic fibrosis and mitigates severity of illness in experimental murine methicillin-resistant Staphylococcus aureus infection

MEK1/2抑制剂可降低囊性纤维化患者巨噬细胞的促炎反应,并减轻实验性小鼠耐甲氧西林金黄色葡萄球菌感染的病情严重程度。

Mithu De,Gregory Serpa,Eryn Zuiker,Katherine B Hisert,W Conrad Liles,Anne M Manicone,Emily A Hemann,Matthew E Long

Acute exposure to electronic cigarette components alters mRNA expression of pre-osteoblasts

急性接触电子烟成分会改变前成骨细胞的mRNA表达。

Dabdoub, Shareef M; Greenlee, Ashley; Abboud, George; Brengartner, Lexie; Zuiker, Eryn; Gorr, Matthew W; Wold, Loren E; Kumar, Purnima S; Cray, James

A crossover study evaluating the sex-dependent and sensitizing effects of sleep deprivation using a nociceptive test battery in healthy subjects

一项交叉研究,采用伤害性感受测试组评估睡眠剥夺对健康受试者的性别依赖性和致敏效应。

Hijma, Hemme; Koopmans, Ingrid; Klaassen, Erica; Doll, Robert Jan; Zuiker, Rob; Groeneveld, Geert Jan

Central nervous system effects of TAK-653, an investigational alpha-amino-3-hydroxy-5-methyl-4-isoxazole receptor (AMPAR) positive allosteric modulator in healthy volunteers

TAK-653(一种在研的α-氨基-3-羟基-5-甲基-4-异恶唑受体(AMPAR)正向变构调节剂)对健康志愿者中枢神经系统的影响

Dijkstra, Francis; O'Donnell, Patricio; Klaassen, Erica; Buhl, Derek; Asgharnejad, Mahnaz; Rosen, Laura; Zuiker, Rob; van Gerven, Joop; Jacobs, Gabriël

Injectable pH-responsive adhesive hydrogels for bone tissue engineering inspired by the underwater attachment strategy of marine mussels

受海洋贻贝水下附着策略启发,用于骨组织工程的可注射 pH 响应性粘合水凝胶

Matthew N George, Xifeng Liu, A Lee Miller 2nd, Eryn Zuiker, Haocheng Xu, Lichun Lu

Driving Performance after Bedtime Administration of Daridorexant, Assessed in a Sensitive Simulator

睡前服用达里多雷生后驾驶性能的敏感模拟器评估

Muehlan, Clemens; Brooks, Sander; Vaillant, Cedric; Meinel, Michael; Jacobs, Gabriël E; Zuiker, Rob G; Dingemanse, Jasper