日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Macrophage Syk-PI3Kγ Inhibits Antitumor Immunity: SRX3207, a Novel Dual Syk-PI3K Inhibitory Chemotype Relieves Tumor Immunosuppression

巨噬细胞 Syk-PI3Kγ 抑制抗肿瘤免疫：新型双重 Syk-PI3K 抑制剂 SRX3207 可缓解肿瘤免疫抑制

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-19-0947
Joshi, Shweta; Liu, Kevin X; Zulcic, Muamera; Singh, Alok R; Skola, Dylan; Glass, Christopher K; Sanders, P Dominick; Sharabi, Andrew B; Pham, Timothy V; Tamayo, Pablo; Shiang, Daniel; Dinh, Huy Q; Hedrick, Catherine C; Morales, Guillermo A; Garlich, Joseph R; Durden, Donald L
巨噬细胞
肿瘤
肿瘤免疫
巨噬细胞
细胞生物学
免疫/内分泌
发表日期：2020
文献求助 收藏

SF2523: Dual PI3K/BRD4 Inhibitor Blocks Tumor Immunosuppression and Promotes Adaptive Immune Responses in Cancer

SF2523：双重PI3K/BRD4抑制剂阻断肿瘤免疫抑制并促进癌症适应性免疫反应

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-18-1206
Joshi, Shweta; Singh, Alok R; Liu, Kevin X; Pham, Timothy V; Zulcic, Muamera; Skola, Dylan; Chun, Hyun Bae; Glass, Christopher K; Morales, Guillermo A; Garlich, Joseph R; Durden, Donald L
BRD4
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2019
文献求助 收藏

A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis

PKC-SHP1信号轴通过降低CBL的酪氨酸磷酸化水平来降低Fcγ受体信号的敏感性，并调节FcγR介导的吞噬作用。

期刊:BMC Immunology
影响因子:2.7
doi:10.1186/1471-2172-15-18
Joshi, Shweta; Singh, Alok Ranjan; Zulcic, Muamera; Durden, Donald L
信号转导
磷酸化
PKC
发表日期：2014
文献求助 收藏

Rac2 controls tumor growth, metastasis and M1-M2 macrophage differentiation in vivo.

Rac2 在体内控制肿瘤生长、转移和 M1-M2 巨噬细胞分化

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0095893
Joshi Shweta, Singh Alok R, Zulcic Muamera, Bao Lei, Messer Karen, Ideker Trey, Dutkowski Janusz, Durden Donald L
肿瘤
发表日期：2014
文献求助 收藏