Genomic pathogenic alterations in the SWI/SNF complex compromise the outcomes of immunotherapy in Chinese patients with KRAS-mutant NSCLC by downregulating STING expression.
SWI/SNF 复合物的基因组致病性改变通过下调 STING 表达，损害了 KRAS 突变型非小细胞肺癌中国患者的免疫治疗效果。
期刊:BMC Medicine
影响因子:8.3
doi:10.1186/s12916-025-04561-6
Gao Lingling, Jiang Jie, Zhu Linlin, Xie Zhi, Chen Yu, Lv Zhiyi, Chen Yuqing, Zhou Wenbin, Chen Ji, Zhong Yumin, Zhang Li, Zeng Penghui, Huang Xiaodan, Yan Wenqing, Lu Danxia, Zhang Shuilian, Guo Weibang, Zhang Dongkun, Zhou Haiyu, Feng Weineng, Wang Binchao, Ke Zunfu, Yang Xuening, Liang Hongling, Zhang Xuchao
