文献库，生知库 | 链接生命科学的每一步

Dong, Runyu; Fei, Yao; He, Yiren; Gao, Peng; Zhang, Bo; Zhu, Menglin; Wang, Zhixiong; Wu, Longfei; Wu, Shuai; Wang, Xiaoming; Cai, Juan; Chen, Zhiqiang; Zuo, Xueliang

乳酸化

细胞生物学

肿瘤

肿瘤免疫

发表日期：2025

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CircRHBDD1 promotes immune escape via IGF2BP2/PD-L1 signaling and acts as a nanotherapeutic target in gastric cancer.

CircRHBDD1 通过 IGF2BP2/PD-L1 信号通路促进免疫逃逸，并可作为胃癌纳米治疗靶点

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/s12967-024-05498-9

Li Yanna, Wang Zhixiong, Gao Peng, Cao Danping, Dong Runyu, Zhu Menglin, Fei Yao, Zuo Xueliang, Cai Juan

The 'Other' subfamily of HECT E3 ubiquitin ligases evaluate the tumour immune microenvironment and prognosis in patients with hepatocellular carcinoma

HECT E3泛素连接酶的“其他”亚家族可评估肝细胞癌患者的肿瘤免疫微环境和预后。

期刊:IET Systems Biology

影响因子:1.9

doi:10.1049/syb2.12086

Dong, Runyu; Wang, Zhixiong; Cao, Danping; Li, Yanna; Fei, Yao; Gao, Peng; Zhu, Menglin; Chen, Zhiqiang; Cai, Juan; Zuo, Xueliang

TH-302-loaded nanodrug reshapes the hypoxic tumour microenvironment and enhances PD-1 blockade efficacy in gastric cancer

载有TH-302的纳米药物可重塑乏氧肿瘤微环境，并增强胃癌中PD-1阻断的疗效。

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-023-02203-8

Wang, Zhixiong; Zhu, Menglin; Dong, Runyu; Cao, Danping; Li, Yanna; Chen, Zhiqiang; Cai, Juan; Zuo, Xueliang

Study on the application value of fluorescent laparoscopy in pancreatic tumor surgery

荧光腹腔镜在胰腺肿瘤手术中的应用价值研究

期刊:Gland Surgery

影响因子:1.6

doi:10.21037/gs-23-331

Xi, Shihang; Zhang, Wei; Qian, Daohai; He, Chiyi; Zuo, Xueliang; Cai, Juan; Li, Lin; Cai, Huiming; Akhil, Chawla; Wang, Xiaoming

Derivation and validation of machine learning models for preoperative estimation of microvascular invasion risk in hepatocellular carcinoma

构建和验证用于肝细胞癌术前微血管侵犯风险评估的机器学习模型

期刊:Annals of Translational Medicine

影响因子:

doi:10.21037/atm-22-2828

Chen, Zhiqiang; Zuo, Xueliang; Zhang, Yao; Han, Guoyong; Zhang, Long; Ding, Wenzhou; Wu, Jindao; Wang, Xuehao

M2 Macrophage-Derived Exosomes Facilitate HCC Metastasis by Transferring α(M) β(2) Integrin to Tumor Cells

M2巨噬细胞来源的外泌体通过将α(M)β(2)整合素转移至肿瘤细胞促进肝细胞癌转移

期刊:Hepatology

影响因子:15.8

doi:10.1002/hep.31432

Wu, Jindao; Gao, Wen; Tang, Qiyun; Yu, Yue; You, Wei; Wu, Zhengshan; Fan, Ye; Zhang, Long; Wu, Chen; Han, Guoyong; Zuo, Xueliang; Zhang, Yao; Chen, Zhiqiang; Ding, Wenzhou; Li, Xiangcheng; Lin, Fengming; Shen, Hongbing; Tang, Jinhai; Zhang, Yaqin; Wang, Xuehao

circHECTD1 facilitates glutaminolysis to promote gastric cancer progression by targeting miR-1256 and activating β-catenin/c-Myc signaling

circHECTD1通过靶向miR-1256并激活β-catenin/c-Myc信号通路促进谷氨酰胺分解，从而促进胃癌进展。

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-019-1814-8

Cai, Juan; Chen, Zhiqiang; Wang, Jinguo; Wang, Junfeng; Chen, Xianjun; Liang, Linhu; Huang, Min; Zhang, Zhengrong; Zuo, Xueliang

circLARP4 induces cellular senescence through regulating miR-761/RUNX3/p53/p21 signaling in hepatocellular carcinoma

circLARP4通过调控miR-761/RUNX3/p53/p21信号通路诱导肝细胞癌细胞衰老

期刊:Cancer Science

影响因子:4.3

doi:10.1111/cas.13901

Chen, Zhiqiang; Zuo, Xueliang; Pu, Liyong; Zhang, Yao; Han, Guoyong; Zhang, Long; Wu, Jindao; Wang, Xuehao

Acidic tumor microenvironment-modulated nanoparticle potentiates gastric cancer photoimmunotherapy

酸性肿瘤微环境调控的纳米颗粒可增强胃癌光免疫疗法的疗效。

Lactylation-Driven HECTD2 Limits the Response of Hepatocellular Carcinoma to Lenvatinib

乳酸化驱动的HECTD2限制了肝细胞癌对乐伐替尼的反应

CircRHBDD1 promotes immune escape via IGF2BP2/PD-L1 signaling and acts as a nanotherapeutic target in gastric cancer.

CircRHBDD1 通过 IGF2BP2/PD-L1 信号通路促进免疫逃逸，并可作为胃癌纳米治疗靶点

The 'Other' subfamily of HECT E3 ubiquitin ligases evaluate the tumour immune microenvironment and prognosis in patients with hepatocellular carcinoma

HECT E3泛素连接酶的“其他”亚家族可评估肝细胞癌患者的肿瘤免疫微环境和预后。

TH-302-loaded nanodrug reshapes the hypoxic tumour microenvironment and enhances PD-1 blockade efficacy in gastric cancer

载有TH-302的纳米药物可重塑乏氧肿瘤微环境，并增强胃癌中PD-1阻断的疗效。

Study on the application value of fluorescent laparoscopy in pancreatic tumor surgery

荧光腹腔镜在胰腺肿瘤手术中的应用价值研究

Derivation and validation of machine learning models for preoperative estimation of microvascular invasion risk in hepatocellular carcinoma

构建和验证用于肝细胞癌术前微血管侵犯风险评估的机器学习模型

M2 Macrophage-Derived Exosomes Facilitate HCC Metastasis by Transferring α(M) β(2) Integrin to Tumor Cells

M2巨噬细胞来源的外泌体通过将α(M)β(2)整合素转移至肿瘤细胞促进肝细胞癌转移

circHECTD1 facilitates glutaminolysis to promote gastric cancer progression by targeting miR-1256 and activating β-catenin/c-Myc signaling

circHECTD1通过靶向miR-1256并激活β-catenin/c-Myc信号通路促进谷氨酰胺分解，从而促进胃癌进展。

circLARP4 induces cellular senescence through regulating miR-761/RUNX3/p53/p21 signaling in hepatocellular carcinoma

circLARP4通过调控miR-761/RUNX3/p53/p21信号通路诱导肝细胞癌细胞衰老