日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Analysis of Methylation Dynamics Reveals a Tissue-Specific, Age-Dependent Decline in 5-Methylcytosine Within the Genome of the Vertebrate Aging Model Nothobranchius furzeri

对甲基化动态的分析揭示了脊椎动物衰老模型物种诺氏鲵(Nothobranchius furzeri)基因组中5-甲基胞嘧啶的组织特异性、年龄依赖性下降。

Zupkovitz, Gordin; Kabiljo, Julijan; Kothmayer, Michael; Schlick, Katharina; Schöfer, Christian; Lagger, Sabine; Pusch, Oliver

Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri

组蛋白去乙酰化酶 1 的表达与短命鱼 Nothobranchius furzeri 的年龄呈负相关

Gordin Zupkovitz, Sabine Lagger, David Martin, Marianne Steiner, Astrid Hagelkruys, Christian Seiser, Christian Schöfer, Oliver Pusch

Phylogenetic analysis and expression profiling of the Klotho gene family in the short-lived African killifish Nothobranchius furzeri

非洲短命鳉鱼 Nothobranchius furzeri 的 Klotho 基因家族的系统发育分析和表达谱分析

Gordin Zupkovitz, Julijan Kabiljo, David Martin, Sylvia Laffer, Christian Schöfer, Oliver Pusch

Distinct chromatin signature of histone H3 variant H3.3 in human cells

人类细胞中组蛋白 H3 变体 H3.3 的独特染色质特征

Luc Snyers, Gordin Zupkovitz, Marlene Almeder, Marianne Fliesser, Anja Stoisser, Klara Weipoltshammer, Christian Schöfer

Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis

组蛋白去乙酰化酶HDAC1和HDAC2在细胞增殖和肿瘤发生中的独特和冗余功能

Jurkin, Jennifer; Zupkovitz, Gordin; Lagger, Sabine; Grausenburger, Reinhard; Hagelkruys, Astrid; Kenner, Lukas; Seiser, Christian

A phosphorylation switch regulates the transcriptional activation of cell cycle regulator p21 by histone deacetylase inhibitors

磷酸化开关通过组蛋白去乙酰化酶抑制剂调节细胞周期调节剂 p21 的转录激活

Elisabeth Simboeck, Anna Sawicka, Gordin Zupkovitz, Silvia Senese, Stefan Winter, Franck Dequiedt, Egon Ogris, Luciano Di Croce, Susanna Chiocca, Christian Seiser

Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production

细胞中组蛋白去乙酰化酶 1 的条件性缺失导致气道炎症增强和 Th2 细胞因子产生增加

Reinhard Grausenburger, Ivan Bilic, Nicole Boucheron, Gordin Zupkovitz, Lamia El-Housseiny, Roland Tschismarov, Yu Zhang, Martina Rembold, Martin Gaisberger, Arnulf Hartl, Michelle M Epstein, Patrick Matthias, Christian Seiser, Wilfried Ellmeier

The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation

细胞周期蛋白依赖性激酶抑制剂p21是组蛋白去乙酰化酶1的关键靶点,而组蛋白去乙酰化酶1是细胞增殖的调节因子。

Zupkovitz, Gordin; Grausenburger, Reinhard; Brunmeir, Reinhard; Senese, Silvia; Tischler, Julia; Jurkin, Jennifer; Rembold, Martina; Meunier, Dominique; Egger, Gerda; Lagger, Sabine; Chiocca, Susanna; Propst, Fritz; Weitzer, Georg; Seiser, Christian

14-3-3 proteins recognize a histone code at histone H3 and are required for transcriptional activation

14-3-3 蛋白识别组蛋白 H3 处的组蛋白密码,并且是转录激活所必需的

Stefan Winter, Elisabeth Simboeck, Wolfgang Fischle, Gordin Zupkovitz, Ilse Dohnal, Karl Mechtler, Gustav Ammerer, Christian Seiser

Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene

转录因子STAT1和IRF1以不同的作用方式启动IFN-γ诱导基因gbp2的转录

Ramsauer, Katrin; Farlik, Matthias; Zupkovitz, Gordin; Seiser, Christian; Kröger, Andrea; Hauser, Hansjörg; Decker, Thomas