日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Application of a high-density microelectrode array assay using a 3D human iPSC-derived brain microphysiological system model for in vitro neurotoxicity screening of environmental compounds.

应用高密度微电极阵列检测技术,利用 3D 人类 iPSC 衍生脑微生理系统模型对环境化合物进行体外神经毒性筛选

Carstens Kelly E, Gronskaya Elena, Jäckel David, Bertoli Jessica, Cuevas Kelvin Ramirez, Dorier Julien, Wang Shan, Lopez-Rodriguez David, Shafer Timothy J, Zurich Marie-Gabrielle, Pamies David

Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility

关于建立微生理系统质量管理体系及其可重复性监测的适用性标准的建议

Pamies, David; Ekert, Jason; Zurich, Marie-Gabrielle; Frey, Olivier; Werner, Sophie; Piergiovanni, Monica; Freedman, Benjamin S; Keong Teo, Adrian Kee; Erfurth, Hendrik; Reyes, Darwin R; Loskill, Peter; Candarlioglu, Pelin; Suter-Dick, Laura; Wang, Shan; Hartung, Thomas; Coecke, Sandra; Stacey, Glyn N; Wagegg, Beren Atac; Dehne, Eva-Maria; Pistollato, Francesca; Leist, Marcel

Novel Strategy to Assess the Neurotoxicity of Organic Solvents Such as Glycol Ethers: Protocol for Combining In Vitro and In Silico Methods With Human-Controlled Exposure Experiments

评估乙二醇醚等有机溶剂神经毒性的新策略:将体外和计算机模拟方法与人体控制暴露实验相结合的方案

Hopf, Nancy B; Suter-Dick, Laura; Huwyler, Jörg; Borgatta, Myriam; Hegg, Lucie; Pamies, David; Paschoud, Hélène; Puligilla, Ramya Deepthi; Reale, Elena; Werner, Sophie; Zurich, Marie-Gabrielle

Organotypic Models to Study Human Glioblastoma: Studying the Beast in Its Ecosystem

利用类器官模型研究人类胶质母细胞瘤:在生态系统中研究这种恶性肿瘤

Pamies, David; Zurich, Marie-Gabrielle; Hartung, Thomas

Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model

抗抑郁药帕罗西汀在iPSC衍生的3D人脑模型中表现出发育神经毒性

Zhong, Xiali; Harris, Georgina; Smirnova, Lena; Zufferey, Valentin; Sá, Rita de Cássia da Silveira E; Baldino Russo, Fabiele; Baleeiro Beltrao Braga, Patricia Cristina; Chesnut, Megan; Zurich, Marie-Gabrielle; Hogberg, Helena T; Hartung, Thomas; Pamies, David

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

关于为监管目的而进行发育神经毒性 (DNT) 测试的创新、转型和实施的必要性的共识声明

Fritsche, Ellen; Grandjean, Philippe; Crofton, Kevin M; Aschner, Michael; Goldberg, Alan; Heinonen, Tuula; Hessel, Ellen V S; Hogberg, Helena T; Bennekou, Susanne Hougaard; Lein, Pamela J; Leist, Marcel; Mundy, William R; Paparella, Martin; Piersma, Aldert H; Sachana, Magdalini; Schmuck, Gabriele; Solecki, Roland; Terron, Andrea; Monnet-Tschudi, Florianne; Wilks, Martin F; Witters, Hilda; Zurich, Marie-Gabrielle; Bal-Price, Anna

Ammonium-induced impairment of axonal growth is prevented through glial creatine

胶质细胞肌酸可阻止铵诱导的轴突生长受损。

Braissant, Olivier; Henry, Hugues; Villard, Anne-Marie; Zurich, Marie-Gabrielle; Loup, Marc; Eilers, Barbara; Parlascino, Gianni; Matter, Edouard; Boulat, Olivier; Honegger, Paul; Bachmann, Claude