日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Results of a phase 1, randomized, placebo-controlled first-in-human trial of griffithsin formulated in a carrageenan vaginal gel

一项针对角叉菜胶阴道凝胶制剂的格里菲辛的1期随机、安慰剂对照首次人体试验结果

Teleshova, Natalia; Keller, Marla J; Fernández Romero, José A; Friedland, Barbara A; Creasy, George W; Plagianos, Marlena G; Ray, Laurie; Barnable, Patrick; Kizima, Larisa; Rodriguez, Aixa; Cornejal, Nadjet; Melo, Claudia; Cruz Rodriguez, Gearoff; Mukhopadhyay, Sampurna; Calenda, Giulia; Sinkar, Shweta U; Bonnaire, Thierry; Wesenberg, Asa; Zhang, Shimin; Kleinbeck, Kyle; Palmer, Kenneth; Alami, Mohcine; O'Keefe, Barry R; Gillevet, Patrick; Hur, Hong; Liang, Yupu; Santone, Gabriela; Fichorova, Raina N; Kalir, Tamara; Zydowsky, Thomas M

Antiviral activity of aframomum melegueta against severe acute respiratory syndrome coronaviruses type 1 and 2

非洲豆蔻对严重急性呼吸综合征冠状病毒 1 型和 2 型的抗病毒活性

Oneil Mahoney, Claudia Melo, Anthony Lockhart, Nadjet Cornejal, Sahar Alsaidi, Qingli Wu, Jim Simon, Rodolfo Juliani, Thomas M Zydowsky, Christine Priano, Adolfina Koroch, José A Fernández Romero

Griffithsin and Carrageenan Combination Results in Antiviral Synergy against SARS-CoV-1 and 2 in a Pseudoviral Model

格里菲辛和角叉菜胶组合在假病毒模型中对 SARS-CoV-1 和 2 产生抗病毒协同作用

Sahar Alsaidi, Nadjet Cornejal, Oneil Mahoney, Claudia Melo, Neeharika Verma, Thierry Bonnaire, Theresa Chang, Barry R O'Keefe, James Sailer, Thomas M Zydowsky, Natalia Teleshova, José A Fernández Romero

Taking the daily grind out of HIV prevention

让艾滋病预防工作不再那么繁琐

Zydowsky, Thomas M

An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques

一种可释放三种抗病毒药物和一种避孕药的阴道环,能够阻断SHIV-RT感染,减少HSV-2病毒脱落,并抑制恒河猴的激素周期。

Derby, Nina; Aravantinou, Meropi; Kenney, Jessica; Ugaonkar, Shweta R; Wesenberg, Asa; Wilk, Jolanta; Kizima, Larisa; Rodriguez, Aixa; Zhang, Shimin; Mizenina, Olga; Levendosky, Keith; Cooney, Michael L; Seidor, Samantha; Gettie, Agegnehu; Grasperge, Brooke; Blanchard, James; Piatak, Michael Jr; Lifson, Jeffrey D; Fernández-Romero, José; Zydowsky, Thomas M; Robbiani, Melissa

MZC Gel Inhibits SHIV-RT and HSV-2 in Macaque Vaginal Mucosa and SHIV-RT in Rectal Mucosa

MZC 凝胶可抑制猕猴阴道粘膜中的 SHIV-RT 和 HSV-2 以及直肠粘膜中的 SHIV-RT

Giulia Calenda, Guillermo Villegas, Patrick Barnable, Claudia Litterst, Keith Levendosky, Agegnehu Gettie, Michael L Cooney, James Blanchard, José A Fernández-Romero, Thomas M Zydowsky, Natalia Teleshova

A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α4β7 and Fails to Prevent Mucosal Transmission of SHIV-SF162P3

一种与 MAdCAM-1 竞争的小分子激活整合素 α4β7,但未能阻止 SHIV-SF162P3 的粘膜传播

Arrode-Brusés, Géraldine; Goode, Diana; Kleinbeck, Kyle; Wilk, Jolanta; Frank, Ines; Byrareddy, Siddappa; Arthos, James; Grasperge, Brooke; Blanchard, James; Zydowsky, Thomas; Gettie, Agegnehu; Martinelli, Elena

Correction: A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin α4β7 and Fails to Prevent Mucosal Transmission of SHIV-SF162P3

更正:一种与 MAdCAM-1 竞争的小分子激活整合素 α4β7,但未能阻止 SHIV-SF162P3 的粘膜传播

Arrode-Brusés, Géraldine; Goode, Diana; Kleinbeck, Kyle; Wilk, Jolanta; Frank, Ines; Byrareddy, Siddappa; Arthos, James; Grasperge, Brooke; Blanchard, James; Zydowsky, Thomas; Gettie, Agegnehu; Martinelli, Elena

In Vitro Exposure to PC-1005 and Cervicovaginal Lavage Fluid from Women Vaginally Administered PC-1005 Inhibits HIV-1 and HSV-2 Infection in Human Cervical Mucosa

体外暴露于PC-1005和阴道给药PC-1005女性的宫颈阴道灌洗液可抑制人宫颈黏膜中的HIV-1和HSV-2感染

Villegas, Guillermo; Calenda, Giulia; Zhang, Shimin; Mizenina, Olga; Kleinbeck, Kyle; Cooney, Michael L; Hoesley, Craig J; Creasy, George W; Friedland, Barbara; Fernández-Romero, José A; Zydowsky, Thomas M; Teleshova, Natalia

Multipurpose Prevention Approaches with Antiretroviral-Based Formulations

基于抗逆转录病毒制剂的多用途预防方法

Jean-Pierre, Ninochka; Barnable, Patrick; Kizima, Larisa; Rodríguez, Aixa; Seidor, Samantha; Cooney, Michael L; Clark, Meredith R; Doncel, Gustavo F; Robbiani, Melissa; Zydowsky, Thomas M; Teleshova, Natalia; Fernández-Romero, José A