日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B

ISRIB的结合揭示了核苷酸交换因子eIF2B中的一个调控位点。

Zyryanova, Alisa F; Weis, Félix; Faille, Alexandre; Alard, Akeel Abo; Crespillo-Casado, Ana; Sekine, Yusuke; Harding, Heather P; Allen, Felicity; Parts, Leopold; Fromont, Christophe; Fischer, Peter M; Warren, Alan J; Ron, David

Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum

PDI扩散受阻和钙耗竭内质网平衡的还原性转变

Avezov, Edward; Konno, Tasuku; Zyryanova, Alisa; Chen, Weiyue; Laine, Romain; Crespillo-Casado, Ana; Melo, Eduardo Pinho; Ushioda, Ryo; Nagata, Kazuhiro; Kaminski, Clemens F; Harding, Heather P; Ron, David

Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants.

谷胱甘肽耗竭的内质网中蛋白质的完整性折叠表明存在替代的蛋白质硫醇还原剂

Tsunoda Satoshi, Avezov Edward, Zyryanova Alisa, Konno Tasuku, Mendes-Silva Leonardo, Pinho Melo Eduardo, Harding Heather P, Ron David

Uncoupling proteostasis and development in vitro with a small molecule inhibitor of the pancreatic endoplasmic reticulum kinase, PERK.

利用胰腺内质网激酶 PERK 的小分子抑制剂在体外解偶联蛋白质稳态和发育

Harding Heather P, Zyryanova Alisa F, Ron David