Chronic kidney failure mineral bone disorder leads to a permanent loss of hematopoietic stem cells through dysfunction of the stem cell niche
慢性肾功能衰竭引起的矿物质骨代谢紊乱会导致造血干细胞永久性丧失,其机制是通过破坏干细胞微环境。
期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-018-33979-7
Aleksinskaya, Marina A; Monge, Matthieu; Siebelt, Michiel; Slot, Edith M; Koekkoek, Karin M; de Bruin, Ruben G; Massy, Ziad A; Weinans, Harrie; Rabelink, Ton J; Fibbe, Willem E; van Zonneveld, Anton Jan; van Pel, Melissa