Peptide-loaded Langerhans cells, despite increased IL15 secretion and T-cell activation in vitro, elicit antitumor T-cell responses comparable to peptide-loaded monocyte-derived dendritic cells in vivo
尽管在体外，载肽的朗格汉斯细胞 IL15 分泌和 T 细胞活化增加，但在体内，其引发的抗肿瘤 T 细胞反应与载肽的单核细胞衍生的树突状细胞相当
期刊:Clinical Cancer Research
影响因子:10
doi:10.1158/1078-0432.CCR-10-3421
Emanuela Romano, Marco Rossi, Gudrun Ratzinger, Maria-Angeles de Cos, David J Chung, Katherine S Panageas, Jedd D Wolchok, Alan N Houghton, Paul B Chapman, Glenn Heller, Jianda Yuan, James W Young
