CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting.
CXCR4 可诱导 CAR-T 细胞在耗竭后形成记忆，从而实现持久的白血病靶向治疗。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67745-x
Itoh-Nakadai Ari, Liang Minggao, Shindo Michiho, Bibi Chen, Tomizawa-Murasawa Mariko, Fujiki Saera, Kaneko Akiko, Kanamaru Emi, Hashimoto Mari, Kajita Hiroshi, Ando Yoshinari, Kojima Miki, Moody Jonathan, Iwasaki Makoto, Takagi Shinsuke, Nakagawa Ryo, Agrawal Saumya, Amitani-Iijima Hanae, Sato Kaori, Sorimachi Yuriko, Suzuki Nahoko, Fukami Takehiro, Hanada Kazuharu, Morita Satoshi, Katsura Kazushige, Matsumoto Takehisa, Kobayashi Maiko, Kato Masahiko, Negishi Yasuyuki, Shirouzu Mikako, Najima Yuho, Takubo Keiyo, Hon Chung Chau, Uchida Naoyuki, Taniguchi Shuichi, Momozawa Yukihide, Carninci Piero, Shultz Leonard D, Saito Yoriko, de Hoon Michiel, Shin Jay W, Ishikawa Fumihiko
