日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Whole genome sequencing of hepatitis B virus using tiled amplicon (HEPTILE) and probe based enrichment on Illumina and Nanopore platforms

利用 Illumina 和 Nanopore 平台,采用基于探针的富集技术,通过拼接扩增子(HEPTILE)技术对乙型肝炎病毒进行全基因组测序。

Lumley, Sheila F; Kent, Chris; Jennings, Daisy; Chai, Haiting; Airey, George; Waddilove, Elizabeth; Delphin, Marion; Trebes, Amy; McNaughton, Anna L; Mohammed, Khadija Said; Wilkinson, Sam A J; Wu, Yanxia; MacIntyre-Cockett, George; Kimono, Beatrice; Mbonye, Kwizera Moses; Ojambo, Kevin; Maponga, Tongai G; Tan, Cedric C S; de Lara, Catherine; Martin, Jacqueline; Campbell, James; Van Schalkwyk, Marije; Goedhals, Dominique; Newton, Robert; Barnes, Eleanor; Loman, Nicholas J; Piazza, Paolo; Quick, Joshua; Ansari, M Azim; Matthews, Philippa C

T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses

T细胞检测可区分临床和亚临床SARS-CoV-2感染与交叉反应性抗病毒应答。

Ogbe, Ane; Kronsteiner, Barbara; Skelly, Donal T; Pace, Matthew; Brown, Anthony; Adland, Emily; Adair, Kareena; Akhter, Hossain Delowar; Ali, Mohammad; Ali, Serat-E; Angyal, Adrienn; Ansari, M Azim; Arancibia-Cárcamo, Carolina V; Brown, Helen; Chinnakannan, Senthil; Conlon, Christopher; de Lara, Catherine; de Silva, Thushan; Dold, Christina; Dong, Tao; Donnison, Timothy; Eyre, David; Flaxman, Amy; Fletcher, Helen; Gardner, Joshua; Grist, James T; Hackstein, Carl-Philipp; Jaruthamsophon, Kanoot; Jeffery, Katie; Lambe, Teresa; Lee, Lian; Li, Wenqin; Lim, Nicholas; Matthews, Philippa C; Mentzer, Alexander J; Moore, Shona C; Naisbitt, Dean J; Ogese, Monday; Ogg, Graham; Openshaw, Peter; Pirmohamed, Munir; Pollard, Andrew J; Ramamurthy, Narayan; Rongkard, Patpong; Rowland-Jones, Sarah; Sampson, Oliver; Screaton, Gavin; Sette, Alessandro; Stafford, Lizzie; Thompson, Craig; Thomson, Paul J; Thwaites, Ryan; Vieira, Vinicius; Weiskopf, Daniela; Zacharopoulou, Panagiota; Turtle, Lance; Klenerman, Paul; Goulder, Philip; Frater, John; Barnes, Eleanor; Dunachie, Susanna

First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults

首次人体随机研究,旨在评估基于黑猩猩腺病毒-155病毒载体的呼吸道合胞病毒(RSV)研究疫苗在健康成年人中的安全性和免疫原性,该疫苗表达RSV融合蛋白、核衣壳蛋白和抗终止蛋白。

Cicconi, Paola; Jones, Claire; Sarkar, Esha; Silva-Reyes, Laura; Klenerman, Paul; de Lara, Catherine; Hutchings, Claire; Moris, Philippe; Janssens, Michel; Fissette, Laurence A; Picciolato, Marta; Leach, Amanda; Gonzalez-Lopez, Antonio; Dieussaert, Ilse; Snape, Matthew D

Novel genetically-modified chimpanzee adenovirus and MVA-vectored respiratory syncytial virus vaccine safely boosts humoral and cellular immunity in healthy older adults

新型基因改造的黑猩猩腺病毒和MVA载体呼吸道合胞病毒疫苗可安全增强健康老年人的体液免疫和细胞免疫。

Green, Christopher A; Sande, Charles J; Scarselli, Elisa; Capone, Stefania; Vitelli, Alessandra; Nicosia, Alfredo; Silva-Reyes, Laura; Thompson, Amber J; de Lara, Catherine M; Taylor, Kathryn S; Haworth, Kathryn; Hutchings, Claire L; Cargill, Tamsin; Angus, Brian; Klenerman, Paul; Pollard, Andrew J

Illumina and Nanopore methods for whole genome sequencing of hepatitis B virus (HBV)

利用 Illumina 和 Nanopore 方法对乙型肝炎病毒 (HBV) 进行全基因组测序

McNaughton, Anna L; Roberts, Hannah E; Bonsall, David; de Cesare, Mariateresa; Mokaya, Jolynne; Lumley, Sheila F; Golubchik, Tanya; Piazza, Paolo; Martin, Jacqueline B; de Lara, Catherine; Brown, Anthony; Ansari, M Azim; Bowden, Rory; Barnes, Eleanor; Matthews, Philippa C

Adenoviral vaccine induction of CD8+ T cell memory inflation: Impact of co-infection and infection order

腺病毒疫苗诱导CD8+ T细胞记忆扩增:合并感染和感染顺序的影响

Lee, Lian N; Bolinger, Beatrice; Banki, Zoltan; de Lara, Catherine; Highton, Andrew J; Colston, Julia M; Hutchings, Claire; Klenerman, Paul

Adenoviral Vector Vaccination Induces a Conserved Program of CD8(+) T Cell Memory Differentiation in Mouse and Man.

腺病毒载体疫苗接种在小鼠和人类中诱导了 CD8(+) T 细胞记忆分化的保守程序

Bolinger Beatrice, Sims Stuart, Swadling Leo, O'Hara Geraldine, de Lara Catherine, Baban Dilair, Saghal Natasha, Lee Lian Ni, Marchi Emanuele, Davis Mark, Newell Evan, Capone Stefania, Folgori Antonella, Barnes Ellie, Klenerman Paul

Safety and immunogenicity of novel respiratory syncytial virus (RSV) vaccines based on the RSV viral proteins F, N and M2-1 encoded by simian adenovirus (PanAd3-RSV) and MVA (MVA-RSV); protocol for an open-label, dose-escalation, single-centre, phase 1 clinical trial in healthy adults

基于猿猴腺病毒(PanAd3-RSV)和MVA(MVA-RSV)编码的呼吸道合胞病毒(RSV)F、N和M2-1病毒蛋白的新型RSV疫苗的安全性和免疫原性:一项在健康成人中开展的开放标签、剂量递增、单中心I期临床试验方案

Green, C A; Scarselli, E; Voysey, M; Capone, S; Vitelli, A; Nicosia, A; Cortese, R; Thompson, A J; Sande, C S; de Lara, Catherine; Klenerman, P; Pollard, A J

Accelerated in vivo proliferation of memory phenotype CD4+ T-cells in human HIV-1 infection irrespective of viral chemokine co-receptor tropism

人类 HIV-1 感染中记忆表型 CD4+ T 细胞的体内增殖加速,与病毒趋化因子共受体嗜性无关

Zhang, Yan; de Lara, Catherine; Worth, Andrew; Hegedus, Andrea; Laamanen, Karoliina; Beverley, Peter; Macallan, Derek

CXCR6 is a marker for protective antigen-specific cells in the lungs after intranasal immunization against Mycobacterium tuberculosis

CXCR6是经鼻内接种结核分枝杆菌疫苗后肺部保护性抗原特异性细胞的标志物

Lee, Lian Ni; Ronan, Edward O; de Lara, Catherine; Franken, Kees L M C; Ottenhoff, Tom H M; Tchilian, Elma Z; Beverley, Peter C L