Carvedilol decrease IL-1β and TNF-α, inhibits MMP-2, MMP-9, COX-2, and RANKL expression, and up-regulates OPG in a rat model of periodontitis.
卡维地洛可降低IL-1β和TNF-α的水平，抑制MMP-2、MMP-9、COX-2和RANKL的表达，并上调OPG在牙周炎大鼠模型中的表达
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0066391
de Araújo Júnior Raimundo Fernandes, Souza Tatiana Oliveira, de Medeiros Caroline Addison Xavier, de Souza Lélia Batista, Freitas Maria de Lourdes, de Lucena Hévio Freitas, do Socorro Costa Feitosa Alves Maria, de Araújo Aurigena Antunes
