日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Butyrate-producing gut bacterium Faecalibacterium prausnitzii protects against bacterial pneumonia

产生丁酸的肠道细菌普拉梭菌(Faecalibacterium prausnitzii)可预防细菌性肺炎

Kullberg, Robert F J; van Linge, Christine C A; de Vos, Alex F; Brands, Xanthe; Bui, Thi Phuong Nam; Butler, Joe M; Faber, Daniël R; Verhoeven, Aswin; van den Wijngaard, René M; de Jonge, Wouter J; Nieuwdorp, Max; van der Poll, Tom; Haak, Bastiaan W; Wiersinga, W Joost

The proteomic landscape of blood monocytes in community-acquired pneumonia

社区获得性肺炎中血液单核细胞的蛋白质组学图谱

Chouchane, Osoul; Michels, Erik H A; Leite, Giuseppe G F; de Vos, Alex F; de Brabander, Justin; Butler, Joe M; Brands, Xanthe; Haak, Bastiaan W; Klarenbeek, Augustijn M; Wiersinga, W Joost; Scicluna, Brendon P; van 't Veer, Cornelis; Kaas, Kathrine F; Petrosius, Valdemaras; Schoof, Erwin M; van der Poll, Tom

Effect of the gut microbiota-derived tryptophan metabolite indole-3-acetic acid in pneumonia

肠道菌群来源的色氨酸代谢产物吲哚-3-乙酸对肺炎的影响

Kullberg, Robert F J; van Linge, Christine C A; Haak, Bastiaan W; Paul, Prasanjit S; Butler, Joe M; Wolff, Nora; van Engelen, Tjitske S R; Sikkens, Jonne J; Bomers, Marije K; Lefèvre, Antoine; Cremer, Olaf L; Roelofs, Joris J T H; Sovran, Bruno; van den Wijngaard, René; de Vos, Alex F; de Jonge, Wouter J; van der Poll, Tom; Wiersinga, W Joost

Role of Liver Kinase 1B in Platelet Activation and Host Defense During Klebsiella pneumoniae-Induced Pneumosepsis

肝激酶1B在肺炎克雷伯菌引起的肺炎脓毒症中血小板活化和宿主防御中的作用

Chouchane, Osoul; Léopold, Valentine; van Linge, Christine C A; de Vos, Alex F; Roelofs, Joris J T H; van 't Veer, Cornelis; van der Poll, Tom

The Sirt1 Activator SRT1720 Mitigates Human Monocyte Activation and Improves Outcome During Gram-Negative Pneumosepsis in Mice

Sirt1激活剂SRT1720可减轻人单核细胞活化并改善小鼠革兰氏阴性肺炎败血症的预后

Blot, Mathieu; Léopold, Valentine; de Beer, Regina; Florquin, Sandrine; Butler, Joe M; Van't Veer, Cornelis; de Vos, Alex F; van der Poll, Tom

Role of Myeloid Cell Glucose Transporter 1 in the Host Response During Pneumonia Caused by Streptococcus pneumoniae

髓系细胞葡萄糖转运蛋白1在肺炎链球菌引起的肺炎宿主反应中的作用

Pereverzeva, Liza; Léopold, Valentine; Saris, Anno; Schuurman, Alex R; Butler, Joe M; Reijnders, Tom D Y; Roelofs, Joris J T H; Faber, Daniël R; Wiersinga, W Joost; Van't Veer, Cornelis; de Vos, Alex F; van der Poll, Tom

Uncovering metabolic pathways in human alveolar macrophages in response to lipopolysaccharide

揭示人肺泡巨噬细胞对脂多糖的代谢反应途径

van Linge, Christine C A; Michels, Erik H A; Pereverzeva, Liza; de Beer, Regina; Klarenbeek, Augustijn M; Schomakers, Bauke V; van Weeghel, Michel; Houtkooper, Riekelt H; Wiersinga, W Joost; Bonta, Peter I; Annema, Jouke T; van der Poll, Tom; de Vos, Alex F

mTOR inhibition impacts the flagellin-augmented inflammatory and antimicrobial response of human airway epithelial cells to Pseudomonas aeruginosa

mTOR抑制影响人呼吸道上皮细胞对铜绿假单胞菌的鞭毛蛋白增强的炎症和抗菌反应

van Linge, Christine C A; Hulme, Katina D; Peters-Sengers, Hessel; Kullberg, Robert F J; de Jong, Menno D; Russell, Colin A; de Vos, Alex F; van der Poll, Tom

Topical adjunctive treatment with flagellin augments pulmonary neutrophil responses and reduces bacterial dissemination in multidrug-resistant K. pneumoniae infection

局部应用鞭毛蛋白辅助治疗可增强肺部中性粒细胞反应,并减少多重耐药肺炎克雷伯菌感染中的细菌播散。

van Linge, Christine C A; Kullberg, Robert F J; Chouchane, Osoul; Roelofs, Joris J T H; Goessens, Wil H F; van 't Veer, Cornelis; Sirard, Jean-Claude; de Vos, Alex F; van der Poll, Tom

Proteomic profiling of neutrophils and plasma in community-acquired pneumonia reveals crucial proteins in diverse biological pathways linked to clinical outcome

对社区获得性肺炎患者中性粒细胞和血浆的蛋白质组学分析揭示了与临床结果相关的多种生物通路中的关键蛋白。

Michels, Erik H A; Chouchane, Osoul; de Brabander, Justin; de Vos, Alex F; Faber, Daniël R; Douma, Renée A; Smit, Eva R; Wiersinga, W Joost; van den Biggelaar, Maartje; van der Poll, Tom; Hoogendijk, Arie J