日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Biomarker recommendation for PD-1/PD-L1 immunotherapy development in pediatric cancer based on digital image analysis of PD-L1 and immune cells

基于 PD-L1 和免疫细胞的数字图像分析,为儿童癌症 PD-1/PD-L1 免疫疗法开发提供生物标志物建议

Manuel A Silva, Nicolas Triltsch, Simon Leis, Ivan Kanchev, Tze Heng Tan, Benjamine Van Peel, Marian Van Kerckhoven, Vanessa Deschoolmeester, Johannes Zimmermann

In vitro study of the Polo-like kinase 1 inhibitor volasertib in non-small-cell lung cancer reveals a role for the tumor suppressor p53

Polo 样激酶 1 抑制剂 volasertib 在非小细胞肺癌中的体外研究揭示了肿瘤抑制因子 p53 的作用

Jolien Van den Bossche, Christophe Deben, Ines De Pauw, Hilde Lambrechts, Christophe Hermans, Vanessa Deschoolmeester, Julie Jacobs, Pol Specenier, Patrick Pauwels, Jan Baptist Vermorken, Marc Peeters, Filip Lardon, An Wouters

Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines

阿法替尼同时靶向 EGFR、HER2 和 HER4,可克服头颈部鳞状细胞癌细胞系中内在和获得性的西妥昔单抗耐药性

Ines De Pauw, Filip Lardon, Jolien Van den Bossche, Hasan Baysal, Erik Fransen, Vanessa Deschoolmeester, Patrick Pauwels, Marc Peeters, Jan Baptist Vermorken, An Wouters

Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation

揭示癌症相关成纤维细胞中 CD70 阳性亚群,其特征是促迁移活性和旺盛的调节性 T 细胞积累

Julie Jacobs, Vanessa Deschoolmeester, Karen Zwaenepoel, Tal Flieswasser, Christophe Deben, Jolien Van den Bossche, Christophe Hermans, Christian Rolfo, Marc Peeters, Olivier De Wever, Filip Lardon, Vasiliki Siozopoulou, Evelien Smits, Patrick Pauwels

Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress

非小细胞肺癌细胞中缺氧诱导的顺铂耐药性由 HIF-1α 和突变型 p53 介导,可通过诱导氧化应激来克服

Christophe Deben, Vanessa Deschoolmeester, Jorrit De Waele, Julie Jacobs, Jolien Van den Bossche, An Wouters, Marc Peeters, Christian Rolfo, Evelien Smits, Filip Lardon, Patrick Pauwels

Towards Prognostic Profiling of Non-Small Cell Lung Cancer: New Perspectives on the Relevance of Polo-Like Kinase 1 Expression, the TP53 Mutation Status and Hypoxia

非小细胞肺癌的预后分析:Polo 样激酶 1 表达、TP53 突变状态和缺氧相关性的新视角

Jolien Van den Bossche, Christophe Deben, Ken Op de Beeck, Vanessa Deschoolmeester, Christophe Hermans, Ines De Pauw, Julie Jacobs, Paul Van Schil, Jan Baptist Vermorken, Patrick Pauwels, Marc Peeters, Filip Lardon, An Wouters

MDM2 SNP309 and SNP285 Act as Negative Prognostic Markers for Non-small Cell Lung Cancer Adenocarcinoma Patients

MDM2 SNP309 和 SNP285 可作为非小细胞肺癌腺癌患者的不良预后标志物

Deben, Christophe; Op de Beeck, Ken; Van den Bossche, Jolien; Jacobs, Julie; Lardon, Filip; Wouters, An; Peeters, Marc; Van Camp, Guy; Rolfo, Christian; Deschoolmeester, Vanessa; Pauwels, Patrick

Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy

顺铂联合抗CD70治疗非小细胞肺癌的临床前数据:联合治疗时代的绝佳搭配

Julie Jacobs, Vanessa Deschoolmeester, Christian Rolfo, Karen Zwaenepoel, Jolien Van den Bossche, Christophe Deben, Karen Silence, Hans de Haard, Christophe Hermans, Sylvie Rottey, Christel Vangestel, Filip Lardon, Evelien Smits, Patrick Pauwels

Better to be alone than in bad company: The antagonistic effect of cisplatin and crizotinib combination therapy in non-small cell lung cancer

宁可独处也不要与坏人为伍:顺铂和克唑替尼联合治疗在非小细胞肺癌中的拮抗作用

Van Der Steen, Nele; Deben, Christophe; Deschoolmeester, Vanessa; Wouters, An; Lardon, Filip; Rolfo, Christian; Germonpré, Paul; Giovannetti, Elisa; Peters, Godefridus J; Pauwels, Patrick

Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect

结直肠癌免疫检查点调节:最新进展及预期

Jacobs, Julie; Smits, Evelien; Lardon, Filip; Pauwels, Patrick; Deschoolmeester, Vanessa