日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Multivalent Atezolizumab-Liposome Conjugates as Active Immunotherapeutic Platforms for Enhanced PD-L1 Blockade in Melanoma

多价阿特珠单抗-脂质体偶联物作为增强黑色素瘤PD-L1阻断的活性免疫治疗平台

期刊:International Journal of Nanomedicine
影响因子:6.5
doi:10.2147/IJN.S561111
Cheng, Ziyun; Amin, Mohamadreza; van Brakel, Mandy; Sacchetti, Andrea; Kim, Robbert Q; Seynhaeve, Ann L B; Debets, Reno; Ten Hagen, Timo L M
PD-L1
黑色素瘤
免疫/内分泌
发表日期：2026
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CXCL10 Secreted by Pericytes Mediates TNFα-Induced Vascular Leakage in Tumors and Enhances Extravasation of Nanoparticle-Based Chemotherapeutics.

周细胞分泌的 CXCL10 介导 TNFα 诱导的肿瘤血管渗漏，并增强纳米颗粒化疗药物的外渗

期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-24-3833
Seynhaeve Ann L B, Liu Hui, Priester Marjolein I, Valentijn Mike, van Holten-Neelen Conny, Brouwer Rutger W W, van Brakel Mandy, Dik Willem A, van IJcken Wilfred F J, Debets Reno, Stubbs Andrew P, Ten Hagen Timo L M
肿瘤
发表日期：2025
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A blood-based immune marker for resistance to pembrolizumab in patients with metastatic urothelial cancer

一种用于检测转移性尿路上皮癌患者对帕博利珠单抗耐药性的血液免疫标志物

期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-022-03250-0
Rijnders, Maud; Robbrecht, Debbie G J; Oostvogels, Astrid A M; van Brakel, Mandy; Boormans, Joost L; Aarts, Maureen J B; Balcioglu, Hayri E; Hamberg, Paul; Voortman, Jens; Westgeest, Hans M; Lolkema, Martijn P; de Wit, Ronald; van der Veldt, Astrid A M; Debets, Reno
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2023
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Gene Engineering T Cells with T-Cell Receptor for Adoptive Therapy

利用基因工程改造T细胞，使其表达T细胞受体，用于过继疗法

期刊:Methods in Molecular Biology
影响因子:
doi:10.1007/978-1-0716-2115-8_13
Kortleve, Dian; van Brakel, Mandy; Wijers, Rebecca; Debets, Reno; Hammerl, Dora
T细胞
信号转导
T细胞
细胞生物学
免疫/内分泌
发表日期：2022
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Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic cancer

基于血液的激酶活性谱分析：转移性癌症免疫检查点抑制剂疗效的潜在预测指标

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2020-001607
Hurkmans, Daan P; Verdegaal, Els M E; Hogan, Sabrina A; de Wijn, Rik; Hovestad, Lies; van den Heuvel, Dianne M A; Ruijtenbeek, Rob; Welters, Marij J P; van Brakel, Mandy; Basak, Edwin A; Pinedo, Herbert M; Lamers, Cor H J; van de Werken, Harmen J G; Groten, John P; Debets, Reno; Levesque, Mitchell P; Dummer, Reinhard; Kapiteijn, Ellen; Mathijssen, Ron H J; Aerts, Joachim G J V; van der Burg, Sjoerd H
信号转导
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2020
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CD45RA(+)CCR7(-) CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab

在接受纳武利尤单抗治疗的非小细胞肺癌患者外周血中，缺乏共刺激受体的CD45RA(+)CCR7(-)CD8 T细胞的频率显著升高。

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1186/s40425-019-0608-y
Kunert, Andre; Basak, Edwin A; Hurkmans, Daan P; Balcioglu, Hayri E; Klaver, Yarne; van Brakel, Mandy; Oostvogels, Astrid A M; Lamers, Cor H J; Bins, Sander; Koolen, Stijn L W; van der Veldt, Astrid A M; Sleijfer, Stefan; Mathijssen, Ron H J; Aerts, Joachim G J V; Debets, Reno
肺癌
肿瘤
T细胞
肿瘤免疫
信号转导
CD8
CD45
T细胞
CCR7
细胞生物学
CD4
免疫/内分泌
发表日期：2019
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Targeting melanoma with immunoliposomes coupled to anti-MAGE A1 TCR-like single-chain antibody

利用与抗MAGE A1 TCR样单链抗体偶联的免疫脂质体靶向黑色素瘤

期刊:International Journal of Nanomedicine
影响因子:6.5
doi:10.2147/IJN.S96123
Saeed, Mesha; van Brakel, Mandy; Zalba, Sara; Schooten, Erik; Rens, Joost A P; Koning, Gerben A; Debets, Reno; Ten Hagen, Timo L M
黑色素瘤
MAG
免疫/内分泌
发表日期：2016
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TCR gene transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 epitopes as melanoma-specific immune targets

TCR基因转移：MAGE-C2/HLA-A2和MAGE-A3/HLA-DP4表位作为黑色素瘤特异性免疫靶点

期刊:
影响因子:
doi:10.1155/2012/586314
Straetemans, Trudy; van Brakel, Mandy; van Steenbergen, Sabine; Broertjes, Marieke; Drexhage, Joost; Hegmans, Joost; Lambrecht, Bart N; Lamers, Cor; van Der Bruggen, Pierre; Coulie, Pierre G; Debets, Reno
黑色素瘤
MAG
免疫/内分泌
发表日期：2012
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