Carbohydrate metabolism is perturbed in peroxisome-deficient hepatocytes due to mitochondrial dysfunction, AMP-activated protein kinase (AMPK) activation, and peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) suppression
由于线粒体功能障碍、AMP 活化蛋白激酶 (AMPK) 活化以及过氧化物酶体增殖激活受体 γ 辅激活因子 1α (PGC-1α) 抑制，过氧化物酶体缺乏的肝细胞中的碳水化合物代谢受到干扰
期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1074/jbc.M111.299727
Annelies Peeters, Peter Fraisl, Sjoerd van den Berg, Emiel Ver Loren van Themaat, Antoine Van Kampen, Mark H Rider, Hiroshi Takemori, Ko Willems van Dijk, Paul P Van Veldhoven, Peter Carmeliet, Myriam Baes
