日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

PRC2 loss impairs small cell lung cancer tumorigenesis and enhances sensitivity to G9a/GLP inhibition.

PRC2 缺失会损害小细胞肺癌的肿瘤发生，并增强对 G9a/GLP 抑制剂的敏感性。

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-026-09677-w
Kopparam Jawahar, Chandrasekaran Gayathri, Hulsman Danielle, Pilger Liesa-Marie, Stevers Karen, Song Ji-Ying, Hernandez-Quiles Miguel, Dijkstra Jelmer, Badhai Jitendra, Landman Nick, Vermeulen Michiel, van Lohuizen Maarten
肺癌
细胞生物学
发表日期：2026
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Combined Inhibition of EZH2 and FGFR is Synergistic in BAP1-deficient Malignant Mesothelioma.

EZH2 和 FGFR 的联合抑制对 BAP1 缺陷型恶性间皮瘤具有协同作用

期刊:Cancer Research Communications
影响因子:3.3
doi:10.1158/2767-9764.CRC-23-0276
Badhai Jitendra, Landman Nick, Pandey Gaurav Kumar, Song Ji-Ying, Hulsman Danielle, Krijgsman Oscar, Chandrasekaran Gayathri, Berns Anton, van Lohuizen Maarten
信号转导
发表日期：2024
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Enhancer of Zeste Homolog 2 (EZH2) Contributes to Rod Photoreceptor Death Process in Several Forms of Retinal Degeneration and Its Activity Can Serve as a Biomarker for Therapy Efficacy.

Zeste同源物2增强子（EZH2）在多种视网膜变性中促进视杆感光细胞死亡过程，其活性可作为治疗效果的生物标志物

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms22179331
Mbefo Martial, Berger Adeline, Schouwey Karine, Gérard Xavier, Kostic Corinne, Beryozkin Avigail, Sharon Dror, Dolfuss Hélène, Munier Francis, Tran Hoai Viet, van Lohuizen Maarten, Beltran William A, Arsenijevic Yvan
细胞生物学
发表日期：2021
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Chromatin landscapes of retroviral and transposon integration profiles

逆转录病毒和转座子整合谱的染色质图谱

期刊:PLoS Genetics
影响因子:3.7
doi:10.1371/journal.pgen.1004250
de Jong, Johann; Akhtar, Waseem; Badhai, Jitendra; Rust, Alistair G; Rad, Roland; Hilkens, John; Berns, Anton; van Lohuizen, Maarten; Wessels, Lodewyk F A; de Ridder, Jeroen
微生物学
发表日期：2014
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Applications of DNA integrating elements: Facing the bias bully

DNA整合元件的应用：对抗偏见欺凌

期刊:
影响因子:
doi:10.4161/2159256X.2014.992694
de Jong, Johann; Wessels, Lodewyk F A; van Lohuizen, Maarten; de Ridder, Jeroen; Akhtar, Waseem
发表日期：2014
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Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer

Akt介导的Bmi1磷酸化调节其在小鼠前列腺癌中的致癌潜能、E3连接酶活性和DNA损伤修复活性。

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI57477
Nacerddine, Karim; Beaudry, Jean-Bernard; Ginjala, Vasudeva; Westerman, Bart; Mattiroli, Francesca; Song, Ji-Ying; van der Poel, Henk; Ponz, Olga Balagué; Pritchard, Colin; Cornelissen-Steijger, Paulien; Zevenhoven, John; Tanger, Ellen; Sixma, Titia K; Ganesan, Shridar; van Lohuizen, Maarten
肿瘤
肿瘤免疫
信号转导
Bmi1
前列腺癌
磷酸化
毒理研究
发表日期：2012
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Polycomb function during oogenesis is required for mouse embryonic development.

卵子发生过程中多梳蛋白的功能对于小鼠胚胎发育是必需的

期刊:Genes & Development
影响因子:7.7
doi:10.1101/gad.188094.112
Posfai Eszter, Kunzmann Rico, Brochard Vincent, Salvaing Juliette, Cabuy Erik, Roloff Tim C, Liu Zichuan, Tardat Mathieu, van Lohuizen Maarten, Vidal Miguel, Beaujean Nathalie, Peters Antoine H F M
免疫/内分泌
Mouse
发表日期：2012
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Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression.

双等位基因 SMARCAL1 突变的穿透率与基因表达的环境和遗传紊乱有关

期刊:Human Molecular Genetics
影响因子:3.2
doi:10.1093/hmg/dds083
Baradaran-Heravi Alireza, Cho Kyoung Sang, Tolhuis Bas, Sanyal Mrinmoy, Morozova Olena, Morimoto Marie, Elizondo Leah I, Bridgewater Darren, Lubieniecka Joanna, Beirnes Kimberly, Myung Clara, Leung Danny, Fam Hok Khim, Choi Kunho, Huang Yan, Dionis Kira Y, Zonana Jonathan, Keller Kory, Stenzel Peter, Mayfield Christy, Lücke Thomas, Bokenkamp Arend, Marra Marco A, van Lohuizen Maarten, Lewis David B, Shaw Chad, Boerkoel Cornelius F
ARC
SMARCAL1
发表日期：2012
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GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors

GFAP-Cre介导的Bmi1转基因激活导致垂体肿瘤

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0035943
Westerman, Bart A; Blom, Marleen; Tanger, Ellen; van der Valk, Martin; Song, Ji-Ying; van Santen, Marije; Gadiot, Jules; Cornelissen-Steijger, Paulien; Zevenhoven, John; Prosser, Haydn M; Uren, Anthony; Aronica, Eleonora; van Lohuizen, Maarten
肿瘤
肿瘤免疫
Bmi1
免疫/内分泌
FAP
GFAP
发表日期：2012
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Computational identification of insertional mutagenesis targets for cancer gene discovery

利用计算方法鉴定插入突变靶点以发现癌症基因

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkr447
de Jong, Johann; de Ridder, Jeroen; van der Weyden, Louise; Sun, Ning; van Uitert, Miranda; Berns, Anton; van Lohuizen, Maarten; Jonkers, Jos; Adams, David J; Wessels, Lodewyk F A
肿瘤
肿瘤免疫
发表日期：2011
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