日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Access to Nitrogen-nitrogen Bond-Containing Heterocycles Through Substrate Promiscuity of Piperazate Synthases

哌嗪合成酶底物混杂性促进含氮-氮键杂环化合物的合成

期刊:ACS Catalysis
影响因子:13.1
doi:10.1021/acscatal.5c01237
Li, Yongxin; Osipyan, Angelina; de Kok, Niels A W; Schröder, Simon; Founti, Maria; Fodran, Peter; van Merkerk, Ronald; Maier, Artur; Tischler, Dirk; Schmidt, Sandy
发表日期：2025
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Correction to "Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells"

更正“噻吩并[2,3-d]嘧啶-2,4(1H,3H)-二酮衍生物抑制d-多巴色素互变酶活性并抑制非小细胞肺癌细胞增殖”

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00406
Xiao, Zhangping; Osipyan, Angelina; Song, Shanshan; Chen, Deng; Schut, Reinder A; van Merkerk, Ronald; van der Wouden, Petra E; Cool, Robbert H; Quax, Wim J; Melgert, Barbro N; Poelarends, Gerrit J; Dekker, Frank J
细胞生物学
肿瘤
肿瘤免疫
肺癌
发表日期：2025
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The Promiscuity of Squalene Synthase-Like Enzyme: Dehydrosqualene Synthase, a Natural Squalene Hyperproducer?

角鲨烯合酶样酶的混杂性：脱氢角鲨烯合酶，一种天然的角鲨烯高产量者？

期刊:Journal of Agricultural and Food Chemistry
影响因子:5.7
doi:10.1021/acs.jafc.3c05770
Zheng Guan, Yafeng Song, Marcel de Vries, Hjalmar Permentier, Pieter Tepper, Ronald van Merkerk, Rita Setroikromo, Wim J Quax
信号转导
发表日期：2024
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Insights into taxadiene synthase catalysis and promiscuity facilitated by mutability landscape and molecular dynamics

通过突变景观和分子动力学深入了解紫杉二烯合酶的催化和混杂性

期刊:Planta
影响因子:3.8
doi:10.1007/s00425-024-04363-9
He, Siqi; Abdallah, Ingy I; van Merkerk, Ronald; Quax, Wim J
发表日期：2024
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Tailored photoenzymatic systems for selective reduction of aliphatic and aromatic nitro compounds fueled by light

利用光能选择性还原脂肪族和芳香族硝基化合物的定制光酶系统

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-023-41194-w
Alejandro Prats Luján ,Mohammad Faizan Bhat ,Sona Tsaturyan ,Ronald van Merkerk ,Haigen Fu ,Gerrit J Poelarends
发表日期：2023
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Thieno[2,3- d]pyrimidine-2,4(1 H,3 H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells

噻吩并[2,3-d]嘧啶-2,4（1H,3H）-二酮衍生物抑制d-多巴色素互变异构酶活性并抑制非小细胞肺癌细胞增殖

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.1c01598
Zhangping Xiao, Angelina Osipyan, Shanshan Song, Deng Chen, Reinder A Schut, Ronald van Merkerk, Petra E van der Wouden, Robbert H Cool, Wim J Quax, Barbro N Melgert, Gerrit J Poelarends, Frank J Dekker
肿瘤
肺癌
肿瘤细胞
发表日期：2022
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Development and application of CRISPR-based genetic tools in Bacillus species and Bacillus phages

CRISPR基因编辑工具在芽孢杆菌属和芽孢杆菌噬菌体中的开发与应用

期刊:Journal of Applied Microbiology
影响因子:3.2
doi:10.1111/jam.15704
Song, Yafeng; He, Siqi; Jopkiewicz, Anita; Setroikromo, Rita; van Merkerk, Ronald; Quax, Wim J
发表日期：2022
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Engineering of Multiple Modules to Improve Amorphadiene Production in Bacillus subtilis Using CRISPR-Cas9

利用 CRISPR-Cas9 对多个模块进行工程改造以提高枯草芽孢杆菌中的紫穗槐二烯产量

期刊:Journal of Agricultural and Food Chemistry
影响因子:5.7
doi:10.1021/acs.jafc.1c00498
Yafeng Song, Siqi He, Ingy I Abdallah, Anita Jopkiewicz, Rita Setroikromo, Ronald van Merkerk, Pieter G Tepper, Wim J Quax
微生物学
发表日期：2021
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Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells

针对巨噬细胞移动抑制因子 (MIF) 的蛋白水解靶向嵌合体 (PROTAC) 在肺癌细胞中具有抗增殖活性

期刊:Angewandte Chemie-International Edition
影响因子:
doi:10.1002/anie.202101864
Zhangping Xiao, Shanshan Song, Deng Chen, Ronald van Merkerk, Petra E van der Wouden, Robbert H Cool, Wim J Quax, Gerrit J Poelarends, Barbro N Melgert, Frank J Dekker
肿瘤
肺癌
巨噬细胞
发表日期：2021
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7-Hydroxycoumarins Are Affinity-Based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor

7-羟基香豆素是基于亲和力的荧光探针，用于巨噬细胞迁移抑制因子的竞争性结合研究

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.0c01160
Zhangping Xiao, Deng Chen, Shanshan Song, Ramon van der Vlag, Petra E van der Wouden, Ronald van Merkerk, Robbert H Cool, Anna K H Hirsch, Barbro N Melgert, Wim J Quax, Gerrit J Poelarends, Frank J Dekker
细胞生物学
巨噬细胞
WB
发表日期：2020
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