日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Translational minimal physiologically based pharmacokinetic model for transferrin receptor-mediated brain delivery of antibodies

基于生理学的转化最小药代动力学模型，用于研究转铁蛋白受体介导的抗体脑递送

期刊:MAbs
影响因子:7.3
doi:10.1080/19420862.2025.2515414
Muliaditan, Morris; van Steeg, Tamara J; Avery, Lindsay B; Sun, Wei; Hammond, Timothy R; Hijdra, Diana; Choi, Siak-Leng; Pillai, Nikhil; Leksa, Nina C; Mavroudis, Panteleimon D
信号转导
神经科学
发表日期：2025
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Development of a ribavirin dosing regimen in transplant recipients with chronic hepatitis E virus infection: a population pharmacokinetic and -dynamic model

针对慢性戊型肝炎病毒感染的移植受者，制定利巴韦林给药方案：群体药代动力学和药效学模型

期刊:Journal of Antimicrobial Chemotherapy
影响因子:3.6
doi:10.1093/jac/dkaf183
Mulder, Midas B; van Noort, Martijn; de Man, Robert A; Kamar, Nassim; de Bruijne, Joep; Knoester, Marjolein; Blokzijl, Hans; Vanwolleghem, Thomas; Roosens, Laurence; Izopet, Jacques; Gandia, Peggy; van der Eijk, Annemiek A; Metselaar, Herold J; Ahsman, Maurice J; van Steeg, Tamara J; Hesselink, Dennis A; de Winter, Brenda C M
炎症/感染
肝炎
微生物学
发表日期：2025
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A model-based approach using GSK3772847, an anti-interleukin-33 receptor monoclonal antibody, as a showcase to predict SC administration PK and free target dynamics based on PK and total target measurements after IV administration

以抗白介素-33受体单克隆抗体GSK3772847为例，采用基于模型的方法，根据静脉给药后的药代动力学和总靶点测量结果，预测皮下给药的药代动力学和游离靶点动力学。

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.13234
Berkhout, Jan; Fairman, Dave; van Noort, Martijn; van Steeg, Tamara J
单克隆抗体
信号转导
GSK3
发表日期：2025
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Defining preclinical efficacy with the DNAPK inhibitor AZD7648 in combination with olaparib: a minimal systems pharmacokinetic-pharmacodynamic model

利用最小系统药代动力学-药效学模型，确定DNAPK抑制剂AZD7648联合奥拉帕尼的临床前疗效

期刊:Journal of Pharmacokinetics and Pharmacodynamics
影响因子:2.8
doi:10.1007/s10928-025-09962-x
DeJongh, Joost; Cadogan, Elaine; Davies, Michael; Ramos-Montoya, Antonio; Smith, Aaron; van Steeg, Tamara; Richards, Ryan
发表日期：2025
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High protein intake causes gene-length-dependent transcriptional decline, shortens lifespan and accelerates ageing in progeroid DNA repair-deficient mice.

高蛋白摄入会导致基因长度依赖性转录下降，缩短寿命，并加速早衰症 DNA 修复缺陷小鼠的衰老

期刊:
影响因子:
doi:10.1038/s44324-025-00064-3
van Galen Ivar, Birkisdóttir Maria B, Ozinga Rutger A, Brandt Renata M C, Barnhoorn Sander, Imholz Sandra, van Oostrom Conny T, van der Marel Ricfrid W G N, Smit Kimberly, Rijksen Yvonne M A, Reiling Erwin, van Steeg Harry, Hoeijmakers Jan H J, Dollé Martijn E T, Vermeij Wilbert P
其它
细胞衰老
发表日期：2025
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The Dutch Working Party on Antibiotic Policy (SWAB) Recommendations for the Diagnosis and Management of Febrile Neutropenia in Patients with Cancer

荷兰抗生素政策工作组（SWAB）关于癌症患者发热性中性粒细胞减少症的诊断和治疗建议

期刊:Infectious Diseases and Therapy
影响因子:5.3
doi:10.1007/s40121-022-00700-1
de la Court, J R; Bruns, A H W; Roukens, A H E; Baas, I O; van Steeg, K; Toren-Wielema, M L; Tersmette, M; Blijlevens, N M A; Huis In 't Veld, R A G; Wolfs, T F W; Tissing, W J E; Kyuchukova, Y; Heijmans, J
肿瘤
中性粒细胞
肿瘤免疫
粒细胞
细胞生物学
发表日期：2022
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The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside

利用早衰症DNA修复缺陷小鼠评估抗衰老化合物，阐明了烟酰胺核苷的益处。

期刊:Frontiers in Aging
影响因子:4.3
doi:10.3389/fragi.2022.1005322
Birkisdóttir, María B; van Galen, Ivar; Brandt, Renata M C; Barnhoorn, Sander; van Vliet, Nicole; van Dijk, Claire; Nagarajah, Bhawani; Imholz, Sandra; van Oostrom, Conny T; Reiling, Erwin; Gyenis, Ákos; Mastroberardino, Pier G; Jaarsma, Dick; van Steeg, Harry; Hoeijmakers, Jan H J; Dollé, Martijn E T; Vermeij, Wilbert P
衰老
发表日期：2022
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Corrigendum: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside

更正：使用早衰症DNA修复缺陷小鼠评估抗衰老化合物，以说明烟酰胺核苷的益处

期刊:Frontiers in Aging
影响因子:4.3
doi:10.3389/fragi.2022.1086552
Birkisdóttir, María B; van Galen, Ivar; Brandt, Renata M C; Barnhoorn, Sander; van Vliet, Nicole; van Dijk, Claire; Nagarajah, Bhawani; Imholz, Sandra; van Oostrom, Conny T; Reiling, Erwin; Gyenis, Ákos; Mastroberardino, Pier G; Jaarsma, Dick; van Steeg, Harry; Hoeijmakers, Jan H J; Dollé, Martijn E T; Vermeij, Wilbert P
衰老
发表日期：2022
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Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice

与饮食限制不同，雷帕霉素无法延长早衰症 DNA 修复缺陷小鼠的寿命并减少转录应激

期刊:Aging Cell
影响因子:8
doi:10.1111/acel.13302
María B Birkisdóttir, Dick Jaarsma, Renata M C Brandt, Sander Barnhoorn, Nicole van Vliet, Sandra Imholz, Conny T van Oostrom, Bhawani Nagarajah, Eliana Portilla Fernández, Anton J M Roks, Ype Elgersma, Harry van Steeg, José A Ferreira, Jeroen L A Pennings, Jan H J Hoeijmakers, Wilbert P Vermeij, Ma
信号转导
WB
发表日期：2021
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Prospective validation of a model-informed precision dosing tool for vancomycin in intensive care patients

对重症监护患者万古霉素的基于模型的精准给药工具进行前瞻性验证

期刊:British Journal of Clinical Pharmacology
影响因子:3
doi:10.1111/bcp.14360
Ter Heine, Rob; Keizer, Ron J; van Steeg, Krista; Smolders, Elise J; van Luin, Matthijs; Derijks, Hieronymus J; de Jager, Cornelis P C; Frenzel, Tim; Brüggemann, Roger
发表日期：2020
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