日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

High protein intake causes gene-length-dependent transcriptional decline, shortens lifespan and accelerates ageing in progeroid DNA repair-deficient mice.

高蛋白摄入会导致基因长度依赖性转录下降，缩短寿命，并加速早衰症 DNA 修复缺陷小鼠的衰老

期刊:
影响因子:
doi:10.1038/s44324-025-00064-3
van Galen Ivar, Birkisdóttir Maria B, Ozinga Rutger A, Brandt Renata M C, Barnhoorn Sander, Imholz Sandra, van Oostrom Conny T, van der Marel Ricfrid W G N, Smit Kimberly, Rijksen Yvonne M A, Reiling Erwin, van Steeg Harry, Hoeijmakers Jan H J, Dollé Martijn E T, Vermeij Wilbert P
其它
细胞衰老
发表日期：2025
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The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside

利用早衰症DNA修复缺陷小鼠评估抗衰老化合物，阐明了烟酰胺核苷的益处。

期刊:Frontiers in Aging
影响因子:4.3
doi:10.3389/fragi.2022.1005322
Birkisdóttir, María B; van Galen, Ivar; Brandt, Renata M C; Barnhoorn, Sander; van Vliet, Nicole; van Dijk, Claire; Nagarajah, Bhawani; Imholz, Sandra; van Oostrom, Conny T; Reiling, Erwin; Gyenis, Ákos; Mastroberardino, Pier G; Jaarsma, Dick; van Steeg, Harry; Hoeijmakers, Jan H J; Dollé, Martijn E T; Vermeij, Wilbert P
衰老
发表日期：2022
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Corrigendum: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside

更正：使用早衰症DNA修复缺陷小鼠评估抗衰老化合物，以说明烟酰胺核苷的益处

期刊:Frontiers in Aging
影响因子:4.3
doi:10.3389/fragi.2022.1086552
Birkisdóttir, María B; van Galen, Ivar; Brandt, Renata M C; Barnhoorn, Sander; van Vliet, Nicole; van Dijk, Claire; Nagarajah, Bhawani; Imholz, Sandra; van Oostrom, Conny T; Reiling, Erwin; Gyenis, Ákos; Mastroberardino, Pier G; Jaarsma, Dick; van Steeg, Harry; Hoeijmakers, Jan H J; Dollé, Martijn E T; Vermeij, Wilbert P
衰老
发表日期：2022
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The transcriptomic response to irinotecan in colon carcinoma bearing mice preconditioned by fasting

禁食预处理的荷瘤小鼠对伊立替康的转录组反应

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.26776
Jongbloed, Franny; Huisman, Sander A; van Steeg, Harry; Pennings, Jeroen L A; IJzermans, Jan N M; Dollé, Martijn E T; de Bruin, Ron W F
发表日期：2019
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Immunization with Small Amyloid-β-derived Cyclopeptide Conjugates Diminishes Amyloid-β-Induced Neurodegeneration in Mice

用小分子β-淀粉样蛋白衍生的环肽缀合物进行免疫可减轻小鼠体内β-淀粉样蛋白诱导的神经退行性变

期刊:Journal of Alzheimers Disease
影响因子:3.1
doi:10.3233/JAD-151136
Mulder, Cornelis K; Dong, Yun; Brugghe, Humphrey F; Timmermans, Hans A M; Tilstra, Wichard; Westdijk, Janny; van Riet, Elly; van Steeg, Harry; Hoogerhout, Peter; Eisel, Ulrich L M
神经科学
免疫/内分泌
发表日期：2016
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Controlled induction of DNA double-strand breaks in the mouse liver induces features of tissue ageing

在小鼠肝脏中控制性诱导DNA双链断裂可诱发组织衰老特征

期刊:Nature Communications
影响因子:15.7
doi:10.1038/ncomms7790
White, Ryan R; Milholland, Brandon; de Bruin, Alain; Curran, Samuel; Laberge, Remi-Martin; van Steeg, Harry; Campisi, Judith; Maslov, Alexander Y; Vijg, Jan
衰老
发表日期：2015
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Biomarkers for circadian rhythm disruption independent of time of day

与一天中时间无关的昼夜节律紊乱生物标志物

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0127075
Van Dycke, Kirsten C G; Pennings, Jeroen L A; van Oostrom, Conny T M; van Kerkhof, Linda W M; van Steeg, Harry; van der Horst, Gijsbertus T J; Rodenburg, Wendy
发表日期：2015
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Diurnal Variation of Hormonal and Lipid Biomarkers in a Molecular Epidemiology-Like Setting

在类似分子流行病学的背景下，激素和脂质生物标志物的昼夜变化

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0135652
van Kerkhof, Linda W M; Van Dycke, Kirsten C G; Jansen, Eugene H J M; Beekhof, Piet K; van Oostrom, Conny T M; Ruskovska, Tatjana; Velickova, Nevenka; Kamcev, Nikola; Pennings, Jeroen L A; van Steeg, Harry; Rodenburg, Wendy
免疫/内分泌
发表日期：2015
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Human TP53 polymorphism (rs1042522) modelled in mouse does not affect glucose metabolism and body composition

在小鼠模型中模拟的人类TP53多态性（rs1042522）不影响葡萄糖代谢和身体成分

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep04091
Reiling, Erwin; Speksnijder, Ewoud N; Pronk, Amanda C M; van den Berg, Sjoerd A A; Neggers, Silvia J W; Rietbroek, Ilma; van Steeg, Harry; Dollé, Martijn E T
Human
P53
代谢
发表日期：2014
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The progeroid phenotype of Ku80 deficiency is dominant over DNA-PKCS deficiency

Ku80 缺陷的早衰表型对 DNA-PKCS 缺陷呈显性。

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0093568
Reiling, Erwin; Dollé, Martijn E T; Youssef, Sameh A; Lee, Moonsook; Nagarajah, Bhawani; Roodbergen, Marianne; de With, Piet; de Bruin, Alain; Hoeijmakers, Jan H; Vijg, Jan; van Steeg, Harry; Hasty, Paul
PKC
发表日期：2014
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