van de Graaf Stan F J相关文献与解析，生知库

ATP8B1 Deficiency Causes Phosphodiesterase 4-Mediated Glucagon Resistance and Impaired Gluconeogenesis in Mouse and Human Liver.

ATP8B1 缺乏导致小鼠和人类肝脏中磷酸二酯酶 4 介导的胰高血糖素抵抗和糖异生受损

Chang Jung-Chin, Panhuis Wietse In Het, Hsu Shu-Hao, Duijst Suzanne, Ho-Mok Kam S, van der Heiden Jolie F, Ying Zhixiong, Erdmann Joris I, Vogel Georg F, Junge Norman, Hartleben BjÃ¶rn, Koelink Pim J, van Dijk Sebastian G, Peng Weng Chuan, Verhoeven Arthur J, Oude Elferink Ronald P J, Chen Huey-Ling, van de Graaf Stan F J, Paulusma Coen C

表观遗传

Bile salt signaling and bile salt-based therapies in cardiometabolic disease

胆汁酸信号传导和基于胆汁酸的疗法在心血管代谢疾病中的作用

期刊:Clinical Science

影响因子:7.7

doi:10.1042/CS20230934

Groenen, Claire C J; Nguyen, Thuc-Anh; Paulusma, Coen C; van de Graaf, Stan F J

Combined inhibition of bile salt synthesis and intestinal uptake reduces cholestatic liver damage and colonic bile salts in mice.

胆汁酸合成和肠道吸收的联合抑制可减少小鼠的胆汁淤积性肝损伤和结肠胆汁酸

期刊:Jhep Reports

影响因子:7.5

doi:10.1016/j.jhepr.2023.100917

Kunst Roni F, Bolt Isabelle, van Dasselaar Rychon D J, Nijmeijer Bart A, Beuers Ulrich, Oude Elferink Ronald P J, van de Graaf Stan F J

信号转导

发表日期：2024

文献求助收藏

Bile Salts by the Back Road

后路旁的胆盐

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.4

doi:10.1016/j.jcmgh.2023.05.005

Oude Elferink, Ronald P J; Van De Graaf, Stan F J

发表日期：2023

文献求助收藏

Differential and organ-specific functions of organic solute transporter α and β in experimental cholestasis

实验性胆汁淤积中有机溶质转运蛋白α和β的差异性和器官特异性功能

期刊:Jhep Reports

影响因子:7.5

doi:10.1016/j.jhepr.2022.100463

van de Wiel, Sandra M W; Porteiro, Begoña; Belt, Saskia C; Vogels, Esther W M; Bolt, Isabelle; Vermeulen, Jacqueline L M; de Waart, D Rudi; Verheij, Joanne; Muncan, Vanesa; Oude Elferink, Ronald P J; van de Graaf, Stan F J

发表日期：2022

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Insufficient evidence for NTCP activity in stellate cells

星状细胞中NTCP活性的证据不足

期刊:Gut

影响因子:25.8

doi:10.1136/gutjnl-2021-326452

Kunst, Roni F; Paulusma, Coen C; van de Graaf, Stan F J

细胞生物学

发表日期：2021

文献求助收藏

Targeting the Four Pillars of Enterohepatic Bile Salt Cycling; Lessons From Genetics and Pharmacology

靶向肠肝胆汁酸循环的四大支柱：来自遗传学和药理学的启示

期刊:Hepatology

影响因子:15.8

doi:10.1002/hep.31651

Kunst, Roni F; Verkade, Henkjan J; Oude Elferink, Ronald P J; van de Graaf, Stan F J

发表日期：2021

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OTC intron 4 variations mediate pathogenic splicing patterns caused by the c.386G>A mutation in humans and spf(ash) mice, and govern susceptibility to RNA-based therapies

OTC基因第4内含子变异介导了人类和spf(ash)小鼠中c.386G>A突变引起的致病性剪接模式，并决定了对RNA疗法的敏感性。

期刊:Molecular Medicine

影响因子:6.4

doi:10.1186/s10020-021-00418-9

Sacchetto, Claudia; Peretto, Laura; Baralle, Francisco; Maestri, Iva; Tassi, Francesca; Bernardi, Francesco; van de Graaf, Stan F J; Pagani, Franco; Pinotti, Mirko; Balestra, Dario

OTC

发表日期：2021

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Fracture risk under selective and non-selective PPAR agonists in primary biliary cholangitis

原发性胆汁性胆管炎患者使用选择性和非选择性PPAR激动剂治疗时的骨折风险

NTCP ubiquitination enables HBV infection

NTCP泛素化促进HBV感染

ATP8B1 Deficiency Causes Phosphodiesterase 4-Mediated Glucagon Resistance and Impaired Gluconeogenesis in Mouse and Human Liver.

ATP8B1 缺乏导致小鼠和人类肝脏中磷酸二酯酶 4 介导的胰高血糖素抵抗和糖异生受损

Bile salt signaling and bile salt-based therapies in cardiometabolic disease

胆汁酸信号传导和基于胆汁酸的疗法在心血管代谢疾病中的作用

Combined inhibition of bile salt synthesis and intestinal uptake reduces cholestatic liver damage and colonic bile salts in mice.

胆汁酸合成和肠道吸收的联合抑制可减少小鼠的胆汁淤积性肝损伤和结肠胆汁酸

Bile Salts by the Back Road

后路旁的胆盐

Differential and organ-specific functions of organic solute transporter α and β in experimental cholestasis

实验性胆汁淤积中有机溶质转运蛋白α和β的差异性和器官特异性功能

Insufficient evidence for NTCP activity in stellate cells

星状细胞中NTCP活性的证据不足

Targeting the Four Pillars of Enterohepatic Bile Salt Cycling; Lessons From Genetics and Pharmacology

靶向肠肝胆汁酸循环的四大支柱：来自遗传学和药理学的启示

OTC intron 4 variations mediate pathogenic splicing patterns caused by the c.386G>A mutation in humans and spf(ash) mice, and govern susceptibility to RNA-based therapies

OTC基因第4内含子变异介导了人类和spf(ash)小鼠中c.386G>A突变引起的致病性剪接模式，并决定了对RNA疗法的敏感性。