日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Improved oncolytic and immunostimulatory activity of the spontaneous jin-3 reovirus mutant in preclinical bladder cancer models

在临床前膀胱癌模型中,自发产生的jin-3呼肠孤病毒突变体表现出增强的溶瘤活性和免疫刺激活性

van de Merbel, Arjanneke F; van der Mark, Maaike H; Hensen, Lobke C M; van den Wollenberg, Diana J M; Hoeben, Rob C; Zonneveld, Willemijn C G; Pelger, Rob C M; Kummeling, Maxime T M; van der Horst, Geertje; van der Pluijm, Gabri

Comparison of radioactive and non-radioactive iothalamate and hippuran to assess kidney function

比较放射性和非放射性碘他拉酸和马尿酸评估肾功能

Mohamed, Abdulfataah A A; Gansevoort, Ron T; van de Merbel, Nico C; van Londen, Marco; de Borst, Martin H; Zijlma, Rolf; Junier, Lenneke A T; Heerspink, Hiddo J L; Stevens, Jasper

Assessment of quality control and effect of radiolysis on the in vivo biodistribution of [(177)Lu]Lu-PSMA-I&T

评估质量控制以及辐射分解对[(177)Lu]Lu-PSMA-I&T体内生物分布的影响

Hooijman, Eline L; Ntihabose, Carolline M; Koolen, Stijn L W; Handula, Maryana; Beekman, Savanne; Stuurman, Debra; de Ridder, Corrina; de Jong, Jan R; van de Merbel, Jordy R J P; Rook, Nyah; Aalbersberg, Else A; Ververs, Tessa F F T; Laverman, Peter; Hendrikx, Jeroen J M A; de Blois, Erik

Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models

抗精神病药物哌氟利多在前列腺癌临床前模型中的抗肿瘤作用

van de Merbel, Arjanneke F; van der Mark, Maaike H; Aalders, Tilly; Puhr, Martin; Mehra, Niven; Schalken, Jack; van der Horst, Geertje; van der Pluijm, Gabri

European Bioanalysis Forum recommendation on embracing a context-of-use-driven scientific validation for chromatographic assays in the light of ICH M10

欧洲生物分析论坛建议根据ICH M10指南,采用基于使用情境的科学验证方法对色谱分析进行验证。

Timmerman, Philip; McDougall, Stuart; Adcock, Neil; Arfvidsson, Cecilia; Barfield, Matthew; Blech, Stefan; Cowan, Kyra J; Ferrari, Luca; Greco, Alessandro; Golob, Michaela; Goodwin, Lee; Hughes, Richard; Ivanova, Tsvetelina; Laurén, Anna; Nelson, Robert; Neitzel, Sonja; Verhaeghe, Tom; van de Merbel, Nico; Wright, Mike; White, Stephen

Feedback from a workshop by the European Bioanalysis Forum on assay validation requirements for in vitro assays following the publication of ICH M12 guideline - a plea for context-of-use over ICH M10 standards

欧洲生物分析论坛就ICH M12指南发布后体外检测方法的验证要求举办研讨会,并就此提出反馈意见——呼吁采用更符合实际应用情境而非ICH M10标准的方案。

Timmerman, Philip; White, Steve; Adcock, Neil; Arfvidsson, Cecilia; Barfield, Matthew; Cowan, Kyra; Ferrari, Luca; Golob, Michaela; Goodwin, Lee; Hughes, Richard; Ivanova, Tsvetelina; Laurén, Anna; McDougall, Stuart; Nelson, Robert; van de Merbel, Nico; Verhaeghe, Tom; Wright, Michael

Simultaneous isotyping and semi-quantitation of anti-drug antibodies to an IgG1 biotherapeutic using hybrid LBA-LC-MS/MS.

利用混合 LBA-LC-MS/MS 同时对 IgG1 生物治疗药物的抗药抗体进行同型分型和半定量分析

Schalk Frank B, Guerrieri Davide, Poetzl Johann, van de Merbel Nico C

A New Ex Vivo Model to Study Cardiac Fibrosis in Whole Mouse Hearts

研究小鼠全心脏纤维化的新型体外模型

Boudewijn P T Kruithof, Babak Mousavi Gourabi, Arjanneke F van de Merbel, Marco C DeRuiter, Marie-José Goumans

New advances of the androgen receptor in prostate cancer: report from the 1st International Androgen Receptor Symposium

前列腺癌雄激素受体研究的新进展:第一届国际雄激素受体研讨会报告

Mehralivand, Sherif; Thomas, Christian; Puhr, Martin; Claessens, Frank; van de Merbel, Arjanneke F; Dubrovska, Anna; Jenster, Guido; Bernemann, Christof; Sommer, Ulrich; Erb, Holger H H

The use of surrogate matrices in bioanalytical preclinical safety testing using chromatographic methods: a recommendation from the European Bioanalysis forum

欧洲生物分析论坛关于在采用色谱法进行生物分析临床前安全性测试中使用替代基质的建议

Goodwin, Lee; McDougall, Stuart; Gnoth, Mark Jean; Mascher, Daniel; Ferrari, Luca; Wheller, Robert; Hawthorne, Hayley; Jansat, Josep-Maria; Faber, Joerg; Huber, Peter; Greco, Alessandro; Eggers, Lars F; Sury, Matthias; Karlsson, Jens-Jakob; Sporring, Sune Hove; Globig, Susanne; van de Merbel, Nico; Timmerman, Philip