日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Biomimetic Total Synthesis and Paired Omics Identify an Intermolecular Diels-Alder Reaction as the Key Step in Lugdunomycin Biosynthesis

仿生全合成和配对组学研究表明，分子间Diels-Alder反应是卢格杜霉素生物合成的关键步骤。

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c01883
Uiterweerd, Michiel T; Nuñez Santiago, Isabel; Cunha, Ana V; Havenith, Remco W A; Du, Chao; Zhang, Le; van der Heul, Helga U; Elsayed, Somayah S; Minnaard, Adriaan J; van Wezel, Gilles P
发表日期：2025
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Metabolic engineering of Streptomyces peucetius for biosynthesis of N,N-dimethylated anthracyclines

波塞链霉菌代谢工程用于 N,N-二甲基蒽环类药物的生物合成

期刊:Frontiers in Bioengineering and Biotechnology
影响因子:4.3
doi:10.3389/fbioe.2024.1363803
Mandy B Hulst, Le Zhang, Helga U van der Heul, Chao Du, Somayah S Elsayed, Arina Koroleva, Thadee Grocholski, Dennis P A Wander, Mikko Metsä-Ketelä, Jacques J C Neefjes, Gilles P van Wezel
代谢
发表日期：2024
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Divergence of Classical and C-Ring-Cleaved Angucyclines: Elucidation of Early Tailoring Steps in Lugdunomycin and Thioangucycline Biosynthesis

经典型和C环裂解型安古环素的差异：阐明卢格杜霉素和硫代安古环素生物合成的早期修饰步骤

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.4c00082
Nuutila, Aleksi; Xiao, Xiansha; van der Heul, Helga U; van Wezel, Gilles P; Dinis, Pedro; Elsayed, Somayah S; Metsä-Ketelä, Mikko
发表日期：2024
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Analysing responsible innovation along a value chain-A single-cell protein case study

分析价值链上的负责任创新——以单细胞蛋白为例

期刊:Engineering Biology
影响因子:
doi:10.1049/enb2.12031
Flight, Monica Hoyos; Tait, Joyce; Chronopoulos, Theo; Betancor, Monica; Wischhusen, Pauline; Burton, Emily; O'Neill, Helen Masey; van der Heul, Kim; Hays, John; Rowe, Peter
细胞生物学
单细胞
发表日期：2024
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Unravelling key enzymatic steps in C-ring cleavage during angucycline biosynthesis

揭示安古环素生物合成过程中C环裂解的关键酶促步骤

期刊:Communications Chemistry
影响因子:6.2
doi:10.1038/s42004-023-01059-1
Elsayed, Somayah S; van der Heul, Helga U; Xiao, Xiansha; Nuutila, Aleksi; Baars, Laura R; Wu, Changsheng; Metsä-Ketelä, Mikko; van Wezel, Gilles P
发表日期：2023
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Development of an International SMA Bulbar Assessment for Inter-professional Administration

开发用于跨专业管理的国际脊髓性肌萎缩症延髓评估方法

期刊:Journal of Neuromuscular Diseases
影响因子:3.4
doi:10.3233/JND-221672
Dunaway Young, Sally; McGrattan, Katlyn; Johnson, Emily; van der Heul, Marise; Duong, Tina; Bakke, Merete; Werlauff, Ulla; Pasternak, Amy; Cattaneo, Camilla; Hoffman, Katie; Fanelli, Lavinia; Breaks, Anne; Allison, Kristen; Baranello, Giovanni; Finkel, Richard; Coratti, Giorgia; Lofra, Robert Muni
神经科学
肌萎缩症
发表日期：2023
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4451 On the loss of individual joint controllability and the organization of muscle synergies in the impaired arm following a stroke: A pilot study

4451 中风后患侧手臂个体关节控制能力丧失及肌肉协同作用组织：一项初步研究

期刊:Bulletin of the World Health Organization
影响因子:5.7
doi:10.1017/cts.2020.135
Misdorp, W; Van der Heul, R O; Kim, Dongwon; Koh, Kyung; Baghi, Raziyeh; Lo, Li-Chuan; Zhang, Chunyang; Xu, Dali; Zhang, Li-Qun
中风
心血管
发表日期：2020
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Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway

对路德霉素生物合成途径中一种新型混杂型酮还原酶的功能和结构研究

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.0c00564
Xiao, Xiansha; Elsayed, Somayah S; Wu, Changsheng; van der Heul, Helga U; Metsä-Ketelä, Mikko; Du, Chao; Prota, Andrea E; Chen, Chun-Chi; Liu, Weidong; Guo, Rey-Ting; Abrahams, Jan Pieter; van Wezel, Gilles P
发表日期：2020
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Lugdunomycin, an Angucycline-Derived Molecule with Unprecedented Chemical Architecture

卢格杜诺霉素，一种具有前所未有的化学结构的安古环素衍生物

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.201814581
Wu, Changsheng; van der Heul, Helga U; Melnik, Alexey V; Lübben, Jens; Dorrestein, Pieter C; Minnaard, Adriaan J; Choi, Young Hae; van Wezel, Gilles P
发表日期：2019
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Dolphins' Willingness to Participate (WtP) in Positive Reinforcement Training as a Potential Welfare Indicator, Where WtP Predicts Early Changes in Health Status

海豚参与正强化训练的意愿（WtP）可作为潜在的福利指标，其中WtP能够预测健康状况的早期变化

期刊:Frontiers in Psychology
影响因子:2.9
doi:10.3389/fpsyg.2019.02112
Clegg, Isabella L K; Rödel, Heiko G; Mercera, Birgitta; van der Heul, Sander; Schrijvers, Thomas; de Laender, Piet; Gojceta, Robert; Zimmitti, Martina; Verhoeven, Esther; Burger, Jasmijn; Bunskoek, Paulien E; Delfour, Fabienne
发表日期：2019
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