日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Conformational biosensors delineate endosomal G protein regulation by GPCRs

构象生物传感器揭示了GPCR对内体G蛋白的调控作用

Wysolmerski, Brian; Fisher, Nicole M; Dates, Andrew N; Inoue, Asuka; Blythe, Emily E; von Zastrow, Mark

GPCR-selective effects of endocytosis on cellular signaling through the cAMP/PKA cascade

内吞作用通过 cAMP/PKA 级联反应对细胞信号传导产生 GPCR 选择性影响

Blythe, Emily E; Fagan, Rita R; von Zastrow, Mark

GPR88 localization to primary cilia in neurons is cell-type specific.

GPR88 在神经元初级纤毛中的定位具有细胞类型特异性。

Li Guan Yenni H, Kieffer Brigitte L, von Zastrow Mark, Ehrlich Aliza T

An engineered nanobody inhibitor for molecular-to-circuit control of opioid receptor function

一种用于从分子到回路控制阿片受体功能的工程化纳米抗体抑制剂

Valbret, Zoé; Lamothe-Molina, Paul J; Papadogkonaki, Sofia; Koehl, Antoine; Arafiles, Jan Vincent V; Tuchman, Ziva Shapiro; Fisher, Nicole M; Radoux-Mergault, Arthur; Canziani, Annika; Huang, Gaoyang; von Zastrow, Mark; Kosloff, Mickey; Hackenberger, Christian P R; Manglik, Aashish; Patriarchi, Tommaso; Stoeber, Miriam

Opioid receptors reveal a discrete cellular mechanism of endosomal G protein activation.

阿片受体揭示了内体 G 蛋白激活的一种独特的细胞机制

Fisher Nicole M, von Zastrow Mark

Intersection of GPCR trafficking and cAMP signaling at endomembranes

GPCR转运与cAMP信号在内膜的交汇点

Ripoll, Léa; von Zastrow, Mark; Blythe, Emily E

Role of the G protein-coupled receptor kinase 2/3 N terminus in discriminating the endocytic effects of opioid agonist drugs

G蛋白偶联受体激酶2/3 N端在区分阿片类激动剂药物内吞作用中的作用

Li, Joy; Inoue, Asuka; Manglik, Aashish; von Zastrow, Mark

Conformational biosensors delineate endosomal G protein regulation by GPCRs

构象生物传感器揭示了GPCR对内体G蛋白的调控作用

Wysolmerski, Brian; Blythe, Emily E; von Zastrow, Mark

Endocytosis drives active cAMP signal discrimination among natively co-expressed GPCRs

内吞作用驱动天然共表达的GPCR之间活性cAMP信号的区分

Blythe, Emily E; Fagan, Rita R; von Zastrow, Mark

Sensitive dLight3 for imaging broad-spectrum dopamine events across brain regions

用于对大脑各区域的广谱多巴胺事件进行成像的敏感型dLight3

Roshgadol, Jacob I; Chouinard, Julie A; Majumder, Shouvik; Scott, Erin C; Borges, Katharine; Hagihara, Kenta M; Mancini, Nino; Steveson, Tanner; Kamath, Tarun; Lodder, Bart; MacLennan, Bryan J; Dalangin, Rochelin; Tjahjono, Nikki; Pal, Akash; Soares-Cunha, Carina; Melugin, Patrick R; Marley, Aaron; Mahe, Karan; Kurima, Kiyoto; Takahashi, Sakiko; Nosaka, Dvyne; Murakami, Kazuma; Colgan, Lesley A; Freitas, Peter T; Chaudhuri, Rishidev; Siciliano, Cody A; Rodrigues, Ana João; Gradinaru, Viviana; Von Zastrow, Mark; Podgorski, Kaspar; Sabatini, Bernardo L; Bidaye, Salil S; Hanks, Timothy D; Ji, Na; Wickens, Jeffery R; Inagaki, Hidehiko K; Tian, Lin