日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bleomycin induces fibrotic transformation of bone marrow stromal cells to treat height loss of intervertebral disc through the TGFβR1/Smad2/3 pathway

博来霉素通过TGFβR1/Smad2/3通路诱导骨髓基质细胞纤维化转化,从而治疗椎间盘高度丢失。

Xiao Yang,Zhiqian Chen,Chen Chen,Chen Han,Yifan Zhou,Xunlin Li,Haijun Tian,Xiaofei Cheng,Kai Zhang,An Qin,Tangjun Zhou,Jie Zhao

A Spatiotemporal Characterisation of Redox Molecules in Planarians, with a Focus on the Role of Glutathione during Regeneration

涡虫氧化还原分子的时空表征,重点关注谷胱甘肽在再生过程中的作用

Karolien Bijnens, Vincent Jaenen, Annelies Wouters, Nathalie Leynen, Nicky Pirotte, Tom Artois, Karen Smeets

Incense smoke-induced oxidative stress disrupts tight junctions and bronchial epithelial barrier integrity and induces airway hyperresponsiveness in mouse lungs

香烟引起的氧化应激破坏紧密连接和支气管上皮屏障完整性,并诱导小鼠肺气道高反应性

Norio Yamamoto, Keiko Kan-O, Miyoko Tatsuta, Yumiko Ishii, Tomohiro Ogawa, Seiji Shinozaki, Satoru Fukuyama, Yoichi Nakanishi, Koichiro Matsumoto

Loss of Spry1 reduces growth of BRAFV600-mutant cutaneous melanoma and improves response to targeted therapy

Spry1 的缺失会减缓 BRAFV600 突变皮肤黑色素瘤的生长并改善对靶向治疗的反应

Barbara Montico #, Francesca Colizzi #, Giorgio Giurato, Aurora Rizzo, Annamaria Salvati, Lorena Baboci, Dania Benedetti, Eliana Pivetta, Alessia Covre, Michele Dal Bo, Alessandro Weisz, Agostino Steffan, Michele Maio, Luca Sigalotti, Elisabetta Fratta

Anthrax toxin component, Protective Antigen, protects insects from bacterial infections

炭疽毒素成分、保护性抗原可保护昆虫免受细菌感染

Saleem Alameh, Gloria Bartolo, Summer O'Brien, Elizabeth A Henderson, Leandra O Gonzalez, Stella Hartmann, Christopher P Klimko, Jennifer L Shoe, Christopher K Cote, Laurence K Grill, Anastasia Levitin, Mikhail Martchenko Shilman

Stromal cell-derived factor 1 regulates in vitro sperm migration towards the cumulus-oocyte complex in cattle

基质细胞衍生因子 1 调节牛体外精子向卵丘-卵母细胞复合体的迁移

Kohei Umezu, Kenshiro Hara, Yuuki Hiradate, Takashi Numabe, Kentaro Tanemura

Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway

过度机械负荷通过 gremlin-1-NF-κB 通路促进骨关节炎

Song Ho Chang, Daisuke Mori, Hiroshi Kobayashi, Yoshifumi Mori, Hideki Nakamoto, Keita Okada, Yuki Taniguchi, Shurei Sugita, Fumiko Yano, Ung-Il Chung, Joo-Ri Kim-Kaneyama, Motoko Yanagita, Aris Economides, Ernesto Canalis, Di Chen, Sakae Tanaka, Taku Saito

Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy

通过肿瘤靶向趋化因子递送招募 CD103+ 树突状细胞可增强检查点抑制剂免疫疗法的疗效

John-Michael Williford, Jun Ishihara, Ako Ishihara, Aslan Mansurov, Peyman Hosseinchi, Tiffany M Marchell, Lambert Potin, Melody A Swartz, Jeffrey A Hubbell

Targeting bone morphogenetic protein receptor 2 sensitizes lung cancer cells to TRAIL by increasing cytosolic Smac/DIABLO and the downregulation of X-linked inhibitor of apoptosis protein

靶向骨形态发生蛋白受体 2 通过增加细胞浆 Smac/DIABLO 和下调 X 连锁凋亡抑制蛋白增强肺癌细胞对 TRAIL 的敏感性

Rachel NeMoyer, Arindam Mondal, Mehul Vora, Elaine Langenfeld, Danea Glover, Michael Scott, Lauren Lairson, Christopher Rongo, David J Augeri, Youyi Peng, Salma K Jabbour, John Langenfeld

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

PUMILIO 过度活跃导致 Norad 缺乏的小鼠过早衰老

Florian Kopp, Mahmoud M Elguindy #, Mehmet E Yalvac #, He Zhang, Beibei Chen, Frank A Gillett, Sungyul Lee, Sushama Sivakumar, Hongtao Yu, Yang Xie, Prashant Mishra, Zarife Sahenk, Joshua T Mendell