Most相关文献与解析，生知库 | 链接生命科学的每一步

Wouter Derks #, Julian Rode #, Sofia Collin #, Fabian Rost, Paula Heinke, Anjana Hariharan, Lauren Pickel, Irina Simonova, Enikő Lázár, Evan Graham, Ramadan Jashari, Michaela Andrä, Anders Jeppsson, Mehran Salehpour, Kanar Alkass, Henrik Druid, Christos P Kyriakopoulos, Iosif Taleb, Thirupura S Shan

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细胞生物学

心脏病

The antitumor activity of TGFβ-specific T cells is dependent on IL-6 signaling

TGFβ特异性T细胞的抗肿瘤活性依赖于IL-6信号传导。

期刊:Cellular & Molecular Immunology

影响因子:21.8

doi:10.1038/s41423-024-01238-7

Maria Perez-Penco ，Mikkel Byrdal ，Lucia Lara de la Torre ，Marta Ballester ，Shawez Khan ，Majken Siersbæk ，Inés Lecoq ，Cecilie Oelvang Madsen ，Julie Westerlin Kjeldsen ，Inge Marie Svane ，Morten Hansen ，Marco Donia ，Julia Sidenius Johansen ，Lars Rønn Olsen ，Lars Grøntved ，Inna Markovna Chen ，Luis Arnes ，Morten Orebo Holmström ，Mads Hald Andersen

Regulated GATA1 expression as a universal gene therapy for Diamond-Blackfan anemia

调控GATA1表达作为治疗Diamond-Blackfan贫血症的通用基因疗法

期刊:Cell Stem Cell

影响因子:19.8

doi:10.1016/j.stem.2024.10.012

Richard A Voit ，Xiaotian Liao ，Alexis Caulier ，Mateusz Antoszewski ，Blake Cohen ，Myriam Armant ，Henry Y Lu ，Travis J Fleming ，Elena Kamal ，Lara Wahlster ，Aoife M Roche ，John K Everett ，Angelina Petrichenko ，Mei-Mei Huang ，William Clarke ，Kasiani C Myers ，Craig Forester ，Antonio Perez-Atayde ，Frederic D Bushman ，Danilo Pellin ，Akiko Shimamura ，David A Williams ，Vijay G Sankaran

Novel BRCA1-PLK1-CIP2A axis orchestrates homologous recombination-mediated DNA repair to maintain chromosome integrity during oocyte meiosis

新型 BRCA1-PLK1-CIP2A 轴调控同源重组介导的 DNA 修复，以维持卵母细胞减数分裂期间的染色体完整性

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkae1207

Crystal Lee, Jeong Su Oh

SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer's disease

SIRT2 和 ALDH1A1 是阿尔茨海默病中星形胶质细胞 GABA 生成的关键酶

期刊:Molecular Neurodegeneration

影响因子:14.9

doi:10.1186/s13024-024-00788-8

Mridula Bhalla ,Jinhyeong Joo ,Daeun Kim ,Jeong Im Shin ,Yongmin Mason Park ,Yeon Ha Ju ,Uiyeol Park ,Seonguk Yoo ,Seung Jae Hyeon ,Hyunbeom Lee ,Junghee Lee ,Hoon Ryu ,C Justin Lee

Microglial NLRP3-gasdermin D activation impairs blood-brain barrier integrity through interleukin-1β-independent neutrophil chemotaxis upon peripheral inflammation in mice

在小鼠外周炎症中，小胶质细胞 NLRP3-gasdermin D 激活通过不依赖于白细胞介素-1β 的中性粒细胞趋化作用损害血脑屏障完整性。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-025-56097-1

Sung-Hyun Yoon # ，Chae Youn Kim # ，Eunju Lee ，Changjun Lee ，Kyung-Seo Lee ，Jaeho Lee ，Hana Park ，Bokeum Choi ，Inhwa Hwang ，Junhan Kim ，Tae-Gyun Kim ，Junghyun Son ，Young-Min Hyun ，Seunghee Hong ，Je-Wook Yu

Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice

支配肝脏的迷走神经感觉神经元对于饮食诱导肥胖小鼠肝脂肪变性和焦虑样行为的发生发展至关重要。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-025-56328-5

Jiyeon Hwang ,Sangbhin Lee ,Junichi Okada ,Li Liu ,Jeffrey E Pessin ,Streamson C Chua Jr ,Gary J Schwartz ,Young-Hwan Jo

Therapy-induced senescent cancer cells contribute to cancer progression by promoting ribophorin 1-dependent PD-L1 upregulation

治疗诱导的衰老癌细胞通过促进核糖体蛋白1依赖的PD-L1上调，促进癌症进展。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-54132-1

Hyun Jung Hwang # ，Donghee Kang # ，Jisoo Shin ，Jonghun Jung ，Soyeon Ko ，Kyung Hee Jung ，Soon-Sun Hong ，Ji Eun Park ，Myung Jin Oh ，Hyun Joo An ，Wen-Hao Yang ，Young-Gyu Ko ，Jong-Ho Cha ，Jae-Seon Lee

Hypoxia-tropic delivery of nanozymes targeting transferrin receptor 1 for nasopharyngeal carcinoma radiotherapy sensitization

针对转铁蛋白受体 1 的纳米酶的缺氧递送对鼻咽癌放射治疗增敏

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-025-56134-z

Ruofei Zhang #, Yanfang Shen #, Xiaoying Zhou #, Jianru Li, Hanqing Zhao, Zixia Zhang, Jun Zhao, Hongjun Jin, Shuanshuan Guo, Hui Ding, Guohui Nie, Zhe Zhang, Ying Wang, Xiyun Yan, Kelong Fan5

Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function

通过治疗增强少突胶质细胞生成实现的不完全髓鞘再生足以恢复视觉皮质功能

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-025-56092-6

Gustavo Della-Flora Nunes #, Lindsay A Osso #, Johana A Haynes, Lauren Conant, Michael A Thornton, Michael E Stockton, Katherine A Brassell, Amanda Morris, Yessenia I Mancha Corchado, John A Gaynes, Anthony R Chavez, Michaelanne B Woerner, Deidre A MacKenna, Aryan Alavi, Anne Danks, Alon Poleg-Polsk

A Latent Cardiomyocyte Regeneration Potential in Human Heart Disease

人类心脏病中潜在的心肌细胞再生潜能

The antitumor activity of TGFβ-specific T cells is dependent on IL-6 signaling

TGFβ特异性T细胞的抗肿瘤活性依赖于IL-6信号传导。

Regulated GATA1 expression as a universal gene therapy for Diamond-Blackfan anemia

调控GATA1表达作为治疗Diamond-Blackfan贫血症的通用基因疗法

Novel BRCA1-PLK1-CIP2A axis orchestrates homologous recombination-mediated DNA repair to maintain chromosome integrity during oocyte meiosis

新型 BRCA1-PLK1-CIP2A 轴调控同源重组介导的 DNA 修复，以维持卵母细胞减数分裂期间的染色体完整性

SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer's disease

SIRT2 和 ALDH1A1 是阿尔茨海默病中星形胶质细胞 GABA 生成的关键酶

Microglial NLRP3-gasdermin D activation impairs blood-brain barrier integrity through interleukin-1β-independent neutrophil chemotaxis upon peripheral inflammation in mice

在小鼠外周炎症中，小胶质细胞 NLRP3-gasdermin D 激活通过不依赖于白细胞介素-1β 的中性粒细胞趋化作用损害血脑屏障完整性。

Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice

支配肝脏的迷走神经感觉神经元对于饮食诱导肥胖小鼠肝脂肪变性和焦虑样行为的发生发展至关重要。

Therapy-induced senescent cancer cells contribute to cancer progression by promoting ribophorin 1-dependent PD-L1 upregulation

治疗诱导的衰老癌细胞通过促进核糖体蛋白1依赖的PD-L1上调，促进癌症进展。

Hypoxia-tropic delivery of nanozymes targeting transferrin receptor 1 for nasopharyngeal carcinoma radiotherapy sensitization

针对转铁蛋白受体 1 的纳米酶的缺氧递送对鼻咽癌放射治疗增敏

Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function

通过治疗增强少突胶质细胞生成实现的不完全髓鞘再生足以恢复视觉皮质功能