ChIP相关文献与解析，生知库 | 链接生命科学的每一步

BORIS/CTCFL epigenetically reprograms clustered CTCF binding sites into alternative transcriptional start sites

BORIS/CTCFL 通过表观遗传学方法将聚集的 CTCF 结合位点重编程为替代的转录起始位点

Elena M Pugacheva, Dharmendra Nath Bhatt, Samuel Rivero-Hinojosa, Md Tajmul, Liron Fedida, Emma Price, Yon Ji, Dmitri Loukinov, Alexander V Strunnikov, Bing Ren, Victor V Lobanenkov

信号转导

Inhibition of BRD4 Attenuates ER Stress-induced Renal Ischemic-Reperfusion Injury

BRD4 抑制可减轻内质网应激引起的肾脏缺血再灌注损伤

期刊:International Journal of Biological Sciences

影响因子:8.2

doi:10.7150/ijbs.83040

Paula Diaz-Bulnes, Ramon M Rodríguez, Elisenda Banon-Maneus, María Laura Saiz, Cristian Ruiz Bernet, Viviana Corte-Iglesias, Maria Jose Ramirez-Bajo, Marta Lazo-Rodriguez, Isaac Tamargo-Gómez, Raúl R Rodrigues-Diez, Ana B Sanz, Carmen Diaz-Corte, Marta Ruiz-Ortega, Fritz Diekmann, Ana M Aransay, Car

A human papillomavirus 16 E2-TopBP1 dependent SIRT1-p300 acetylation switch regulates mitotic viral and human protein levels and activates the DNA damage response

人乳头瘤病毒 16 E2-TopBP1 依赖的 SIRT1-p300 乙酰化开关调节有丝分裂病毒和人类蛋白质水平并激活 DNA 损伤反应

期刊:mBio

影响因子:5.1

doi:10.1128/mbio.00676-24

Apurva T Prabhakar, Claire D James, Aya H Youssef, Reafa A Hossain, Ronald D Hill, Molly L Bristol, Xu Wang, Aanchal Dubey, Elmira Karimi, Iain M Morgan

The Transcription Factor Ets1 Influences Axonal Growth via Regulation of Lcn2

转录因子 Ets1 通过调控 Lcn2 影响轴突生长

期刊:Molecular Neurobiology

影响因子:4.6

doi:10.1007/s12035-023-03616-0

Miao Gu #, Xiaodi Li #, Ronghua Wu, Xiao Cheng, Songlin Zhou, Xiaosong Gu

Chronic adolescent stress alters GR-FKBP5 interactions in the hippocampus of adult female rats

慢性青春期压力改变成年雌性大鼠海马中的 GR-FKBP5 相互作用

期刊:Stress-The International Journal on the Biology of Stress

影响因子:2.6

doi:10.1080/10253890.2024.2312467

Sydney Rowson, Mandakh Bekhbat, Sean Kelly, Molly M Hyer, Samya Dyer, David Weinshenker, Gretchen Neigh

Protocol for establishing inducible CRISPRd system for blocking transcription factor-binding sites in human pluripotent stem cells

建立可诱导型 CRISPRd 系统以阻断人类多能干细胞中转录因子结合位点的方案

期刊:STAR Protocols

影响因子:1.3

doi:10.1016/j.xpro.2024.103233

Satoshi Matsui,Joseph R Shiley,Morgan Buckley,Hee-Woong Lim,Yueh-Chiang Hu,Christopher N Mayhew,Makiko Iwafuchi

The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β-catenin Signaling via Epigenetic Dysregulation that Enhances Sp1-β catenin-p300 Interactions in Hepatocellular Carcinoma

孤儿核受体 NR2E3 的缺失通过表观遗传失调增强 Wnt/β-catenin 信号传导，从而增强肝细胞癌中的 Sp1-β catenin-p300 相互作用

期刊:Advanced Science

影响因子:

doi:10.1002/advs.202308539

Yuet-Kin Leung, Sung-Gwon Lee, Jiang Wang, Ponmari Guruvaiah, Nancy J Rusch, Shuk-Mei Ho, Chungoo Park, Kyounghyun Kim

Interaction between estrogen receptor-α and PNPLA3 p.I148M variant drives fatty liver disease susceptibility in women

雌激素受体-α与PNPLA3 p.I148M变异体之间的相互作用导致女性易患脂肪肝

期刊:Nature Medicine

影响因子:58.7

doi:10.1038/s41591-023-02553-8

Alessandro Cherubini #, Mahnoosh Ostadreza #, Oveis Jamialahmadi, Serena Pelusi, Eniada Rrapaj, Elia Casirati, Giulia Passignani, Marjan Norouziesfahani, Elena Sinopoli, Guido Baselli, Clara Meda, Paola Dongiovanni, Daniele Dondossola, Neil Youngson, Aikaterini Tourna, Shilpa Chokshi, Elisabetta Bug

STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma

STING抑制肺腺癌休眠转移灶的再激活

期刊:Nature

影响因子:50.5

doi:10.1038/s41586-023-05880-5

Jing Hu，Francisco J Sánchez-Rivera ，Zhenghan Wang，Gabriela N Johnson，Yu-Jui Ho，Karuna Ganesh ，Shigeaki Umeda，Siting Gan，Adriana M Mujal，Rebecca B Delconte，Jessica P Hampton，Huiyong Zhao，Sanjay Kottapalli，Elisa de Stanchina，Christine A Iacobuzio-Donahue ，Dana Pe'er ，Scott W Lowe，Joseph C Sun，Joan Massagué

DisP-seq reveals the genome-wide functional organization of DNA-associated disordered proteins

DisP-seq 揭示 DNA 相关无序蛋白质的全基因组功能组织

BORIS/CTCFL epigenetically reprograms clustered CTCF binding sites into alternative transcriptional start sites

BORIS/CTCFL 通过表观遗传学方法将聚集的 CTCF 结合位点重编程为替代的转录起始位点

Inhibition of BRD4 Attenuates ER Stress-induced Renal Ischemic-Reperfusion Injury

BRD4 抑制可减轻内质网应激引起的肾脏缺血再灌注损伤

A human papillomavirus 16 E2-TopBP1 dependent SIRT1-p300 acetylation switch regulates mitotic viral and human protein levels and activates the DNA damage response

人乳头瘤病毒 16 E2-TopBP1 依赖的 SIRT1-p300 乙酰化开关调节有丝分裂病毒和人类蛋白质水平并激活 DNA 损伤反应

The Transcription Factor Ets1 Influences Axonal Growth via Regulation of Lcn2

转录因子 Ets1 通过调控 Lcn2 影响轴突生长

Chronic adolescent stress alters GR-FKBP5 interactions in the hippocampus of adult female rats

慢性青春期压力改变成年雌性大鼠海马中的 GR-FKBP5 相互作用

Protocol for establishing inducible CRISPRd system for blocking transcription factor-binding sites in human pluripotent stem cells

建立可诱导型 CRISPRd 系统以阻断人类多能干细胞中转录因子结合位点的方案

The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β-catenin Signaling via Epigenetic Dysregulation that Enhances Sp1-β catenin-p300 Interactions in Hepatocellular Carcinoma

孤儿核受体 NR2E3 的缺失通过表观遗传失调增强 Wnt/β-catenin 信号传导，从而增强肝细胞癌中的 Sp1-β catenin-p300 相互作用

Interaction between estrogen receptor-α and PNPLA3 p.I148M variant drives fatty liver disease susceptibility in women

雌激素受体-α与PNPLA3 p.I148M变异体之间的相互作用导致女性易患脂肪肝

STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma

STING抑制肺腺癌休眠转移灶的再激活