日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A single-nucleus transcriptomic atlas of primate liver aging uncovers the pro-senescence role of SREBP2 in hepatocytes

灵长类肝脏衰老的单核转录组图谱揭示了 SREBP2 在肝细胞中的促衰老作用

Shanshan Yang, Chengyu Liu, Mengmeng Jiang, Xiaoqian Liu, Lingling Geng, Yiyuan Zhang, Shuhui Sun, Kang Wang, Jian Yin, Shuai Ma, Si Wang, Juan Carlos Izpisua Belmonte, Weiqi Zhang, Jing Qu, Guang-Hui Liu

Sex-dependent effects of long-term clozapine or haloperidol medication on red blood cells and liver iron metabolism in Sprague Dawley rats as a model of metabolic syndrome

长期服用氯氮平或氟哌啶醇对 Sprague Dawley 大鼠红细胞和肝脏铁代谢的性别相关影响(作为代谢综合征模型)

Marie-Luise Bouvier, Karin Fehsel, Andrea Schmitt, Eva Meisenzahl-Lechner, Wolfgang Gaebel, Martina von Wilmsdorff

Elimination of Reprogramming Transgenes Facilitates the Differentiation of Induced Pluripotent Stem Cells into Hepatocyte-like Cells and Hepatic Organoids

消除重编程转基因有利于诱导性多能干细胞分化为肝细胞样细胞和肝类器官

Jaemin Jeong, Tae Hun Kim, Myounghoi Kim, Yun Kyung Jung, Kyeong Sik Kim, Sehwan Shim, Hyosun Jang, Won Il Jang, Seung Bum Lee, Dongho Choi

CYP1A2 suppresses hepatocellular carcinoma through antagonizing HGF/MET signaling

CYP1A2 通过拮抗 HGF/MET 信号抑制肝细胞癌

Jianqing Yu, Xianfeng Xia, Yujuan Dong, Zhongqin Gong, Gang Li, George Gong Chen, Paul Bo San Lai

Holistic characterization of single-hepatocyte transcriptome responses to high-fat diet

单肝细胞转录组对高脂饮食反应的整体表征

Sung Rye Park, Chun-Seok Cho, Jingyue Xi, Hyun Min Kang, Jun Hee Lee

Mono-methylindoles induce CYP1A genes and inhibit CYP1A1 enzyme activity in human hepatocytes and HepaRG cells

单甲基吲哚诱导 CYP1A 基因并抑制人类肝细胞和 HepaRG 细胞中的 CYP1A1 酶活性

Barbora Vyhlídalová, Karolína Poulíková, Iveta Bartoňková, Kristýna Krasulová, Jan Vančo, Zdeněk Trávníček, Sridhar Mani, Zdeněk Dvořák

The expression, induction and pharmacological activity of CYP1A2 are post-transcriptionally regulated by microRNA hsa-miR-132-5p

CYP1A2 的表达、诱导和药理活性受 microRNA hsa-miR-132-5p 的转录后调控

Yinting Chen, Linjuan Zeng, Yong Wang, William H Tolleson, Bridgett Knox, Si Chen, Zhen Ren, Lei Guo, Nan Mei, Feng Qian, Kaihong Huang, David Liu, Weida Tong, Dianke Yu, Baitang Ning

Skatole (3-Methylindole) Is a Partial Aryl Hydrocarbon Receptor Agonist and Induces CYP1A1/2 and CYP1B1 Expression in Primary Human Hepatocytes

粪臭素(3-甲基吲哚)是一种部分芳基烃受体激动剂,可诱导人原代肝细胞中 CYP1A1/2 和 CYP1B1 的表达

Martin Krøyer Rasmussen, Patrick Balaguer, Bo Ekstrand, Martine Daujat-Chavanieu, Sabine Gerbal-Chaloin

Differential effects of omeprazole and lansoprazole enantiomers on aryl hydrocarbon receptor in human hepatocytes and cell lines

奥美拉唑和兰索拉唑对映体对人肝细胞和细胞系中芳烃受体的不同影响

Aneta Novotna, Alzbeta Srovnalova, Michaela Svecarova, Martina Korhonova, Iveta Bartonkova, Zdenek Dvorak