日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A microRNA expression signature in infant t(4;11) KMT2A::AFF1+ BCP-ALL uncovers novel therapeutic targets

婴儿t(4;11) KMT2A::AFF1+ BCP-ALL中的microRNA表达特征揭示了新的治疗靶点

期刊:Hemasphere
影响因子:14.6
doi:10.1002/hem3.70353
Malouf, Camille; Duguid, Alasdair; Vrenken, Kirsten S; Leah, Tom; Medhi, Ragini; Camiolo, Giuseppina; Nitsche, Leslie; Jakobczyk, Hélène; Kotecha, Rishi S; Anderson, Richard A; Barrett, Neil A; Smith, Owen P; Stam, Ronald W; Ottersbach, Katrin
AFF1
KMT2A
发表日期：2026
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A microRNA expression signature in infant t(4;11) KMT2A::AFF1+ BCP‐ALL uncovers novel therapeutic targets

婴儿 t(4;11) KMT2A::AFF1+ BCP-ALL 中的 microRNA 表达特征揭示了新的治疗靶点

期刊:Hemasphere
影响因子:14.6
doi:10.1097/HS9.0000000000000809
Papadopoulou, Anastasia; Alvanou, Maria; Karavalakis, George; Tzannou, Ifigeneia; Yannaki, Evangelia; Malouf, Camille; Duguid, Alasdair; Vrenken, Kirsten S; Leah, Tom; Medhi, Ragini; Camiolo, Giuseppina; Nitsche, Leslie; Jakobczyk, Hélène; Kotecha, Rishi S; Anderson, Richard A; Barrett, Neil A; Smith, Owen P; Stam, Ronald W; Ottersbach, Katrin
KMT2A
AFF1
发表日期：2026
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Ontogeny-specific induction of the KMT2A::AFF1-fusion drives development of a distinct CD24 positive pre-leukemic state

个体发育特异性诱导KMT2A::AFF1融合蛋白驱动一种独特的CD24阳性白血病前期状态的发生。

期刊:Leukemia
影响因子:13.4
doi:10.1038/s41375-025-02665-9
Calderón, Ariana S; Ghazanfari, Roshanak; Masoumi, Zahra; Kharazi, Shabnam; Palo, Sara; Lang, Stefan; Žemaitis, Kristijonas; Eldeeb, Mohamed; Subramaniam, Agatheeswaran; Soneji, Shamit; Stam, Ronald W; Bryder, David; Böiers, Charlotta
KMT2A
CD24
白血病
发育与干细胞
CD2
AFF1
发表日期：2025
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Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

利用脂质体纳米颗粒递送靶向KMT2A::AFF1的siRNA抑制t(4;11)急性白血病并增强肝外递送

期刊:Advanced Healthcare Materials
影响因子:9.6
doi:10.1002/adhm.202502019
Nasrullah, Mohammad; Kc, Remant; Rajendran, Amarnath Praphakar; Dezfouli, Saba Abbasi; Kucharski, Cezary; Jiang, Xiaoyan; Gibson, Spencer B; Brandwein, Joseph; Heidenreich, Olaf; Uludağ, Hasan
白血病
KMT2A
AFF1
发表日期：2025
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Blinatumomab-Related Lineage Switch of KMT2A/AFF1-Rearranged B-Lymphoblastic Leukemia to B/Myeloid Mixed-Phenotype Acute Leukemia and Myeloid Sarcoma Causing Spinal Cord Compression

Blinatumomab相关KMT2A/AFF1重排B淋巴母细胞白血病向B/髓系混合表型急性白血病和髓系肉瘤的谱系转换导致脊髓压迫

期刊:Case Reports in Hematology
影响因子:0.7
doi:10.1155/crh/7063561
Fan, Xiaoming; Gupta, Ankita; Dabrowski, Dominik; Rusella, Mirza; Zhai, Qihui J; Wei, Eric X
神经科学
白血病
细胞生物学
KMT2A
AFF1
发表日期：2025
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Proximally biased V(D)J recombination in the clonal evolution of IGH alleles in KMT2A::AFF1 BCP-ALL of all age classes

在所有年龄段的KMT2A::AFF1 BCP-ALL中，IGH等位基因克隆进化过程中存在近端偏向的V(D)J重组

期刊:Hemasphere
影响因子:14.6
doi:10.1002/hem3.71
Müller, Heiko; Dicker, Frank; Bär, Constance; Walter, Wencke; Hutter, Stephan; Nadarajah, Niroshan; Meggendorfer, Manja; Gao, Qingsong; Iacobucci, Ilaria; Mullighan, Charles G; Kern, Wolfgang; Haferlach, Torsten; Haferlach, Claudia
KMT2A
AFF1
发表日期：2024
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Genome editing-induced t(4;11) chromosomal translocations model B cell precursor acute lymphoblastic leukemias with KMT2A-AFF1 fusion

基因组编辑诱导的t(4;11)染色体易位模拟了具有KMT2A-AFF1融合的B细胞前体急性淋巴细胞白血病

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI171030
Pan, Feng; Sarno, Jolanda; Jeong, Johan; Yang, Xin; Jager, Astraea; Gruber, Tanja A; Davis, Kara L; Cleary, Michael L
B细胞
白血病
细胞生物学
KMT2A
AFF1
免疫/内分泌
发表日期：2024
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Functional relevance of circRNA aberrant expression in pediatric acute leukemia with KMT2A::AFF1 fusion

KMT2A::AFF1融合基因在儿童急性白血病中circRNA异常表达的功能相关性

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2023011291
Tretti Parenzan, Caterina; Molin, Anna Dal; Longo, Giorgia; Gaffo, Enrico; Buratin, Alessia; Cani, Alice; Boldrin, Elena; Serafin, Valentina; Guglielmelli, Paola; Vannucchi, Alessandro M; Cazzaniga, Giovanni; Biondi, Andrea; Locatelli, Franco; Meyer, Lueder H; Buldini, Barbara; Te Kronnie, Geertruij; Bresolin, Silvia; Bortoluzzi, Stefania
白血病
circRNA
KMT2A
AFF1
发表日期：2024
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Discovery of fusion circular RNAs in leukemia with KMT2A::AFF1 rearrangements by the new software CircFusion

利用新型软件 CircFusion 发现白血病中存在 KMT2A::AFF1 重排的融合环状 RNA。

期刊:Briefings in Bioinformatics
影响因子:7.7
doi:10.1093/bib/bbac589
Dal Molin, Anna; Tretti Parenzan, Caterina; Gaffo, Enrico; Borin, Cristina; Boldrin, Elena; Meyer, Lueder H; Te Kronnie, Geertruij; Bresolin, Silvia; Bortoluzzi, Stefania
白血病
KMT2A
AFF1
发表日期：2023
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CircAFF1 Is a Circular RNA with a Role in Alveolar Rhabdomyosarcoma Cell Migration

CircAFF1是一种环状RNA，在肺泡横纹肌肉瘤细胞迁移中发挥作用

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines11071893
Alvaro Centrón-Broco,Francesca Rossi,Chiara Grelloni,Raffaele Garraffo,Dario Dattilo,Andrea Giuliani,Gaia Di Timoteo,Alessio Colantoni,Irene Bozzoni,Manuel Beltran Nebot
横纹肌肉瘤
细胞生物学
AFF1
发表日期：2023
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