日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure of the human CTF18-RFC clamp loader bound to PCNA

人类 CTF18-RFC 钳状加载蛋白与 PCNA 结合的结构

Briola, Giuseppina R; Tehseen, Mohammad; Al-Amodi, Amani; Young, Grace; Danazumi, Ammar U; Nguyen, Phong Quoc; Savva, Christos G; Hedglin, Mark; Hamdan, Samir M; De Biasio, Alfredo

Structure of the human CTF18-RFC clamp loader bound to PCNA

人类 CTF18-RFC 钳状加载蛋白与 PCNA 结合的结构

Briola, Giuseppina R; Tehseen, Muhammad; Al-Amodi, Amani; Young, Grace; Danazumi, Ammar U; Nguyen, Phong Quoc; Savva, Christos G; Hedglin, Mark; Hamdan, Samir M; De Biasio, Alfredo

Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC

冷冻电镜揭示了近乎完整的PCNA装载过程以及人类替代夹持装载器CTF18-RFC的独特特征。

He, Qing; Wang, Feng; O'Donnell, Michael E; Li, Huilin

DNA Replication and Sister Chromatid Cohesion 1 (DSCC1) of the Replication Factor Complex CTF18-RFC is Critical for Colon Cancer Cell Growth

复制因子复合物 CTF18-RFC 的 DNA 复制和姐妹染色单体黏连 1 (DSCC1) 对结肠癌细胞生长至关重要

Kim, Jong-Tae; Cho, Hee Jun; Park, Sang Yoon; Oh, Byung Moo; Hwang, Yo Sep; Baek, Kyoung Eun; Lee, Young-Ha; Kim, Hee Cheol; Lee, Hee Gu

Human CTF18-RFC clamp-loader complexed with non-synthesising DNA polymerase ε efficiently loads the PCNA sliding clamp

人类 CTF18-RFC 夹钳装载机与非合成 DNA 聚合酶 ε 复合,可有效装载 PCNA 滑动夹钳

Ryo Fujisawa, Eiji Ohashi, Kouji Hirota, Toshiki Tsurimoto

Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components

新生的染色质捕获蛋白质组学确定 DNA 复制过程中的染色质动力学并识别未知的叉成分

Constance Alabert, Jimi-Carlo Bukowski-Wills, Sung-Bau Lee, Georg Kustatscher, Kyosuke Nakamura, Flavia de Lima Alves, Patrice Menard, Jakob Mejlvang, Juri Rappsilber, Anja Groth

Synthetic lethal genetic interactions that decrease somatic cell proliferation in Caenorhabditis elegans identify the alternative RFC CTF18 as a candidate cancer drug target

在秀丽隐杆线虫中,合成致死基因相互作用会降低体细胞增殖,这表明替代的RFC CTF18可能是一个潜在的癌症药物靶点。

McLellan, Jessica; O'Neil, Nigel; Tarailo, Sanja; Stoepel, Jan; Bryan, Jennifer; Rose, Ann; Hieter, Philip