CTGF相关文献与解析，生知库 | 链接生命科学的每一步

circTGFBR2(3-6) acts as an assembly platform for RNA-binding protein IGF2BP3 and TGFBR1 mRNA to enhance breast cancer cell plasticity.

circTGFBR2(3-6) 作为 RNA 结合蛋白 IGF2BP3 和 TGFBR1 mRNA 的组装平台，增强乳腺癌细胞的可塑性。

期刊:Cell Death and Differentiation

影响因子:15.4

doi:10.1038/s41418-025-01597-2

Wang Qian, Tjokrodirijo Rayman T N, Mei Hailiang, van Veelen Peter A, Ten Dijke Peter, Fan Chuannan

CTGF knockdown in Vero cells reduces autophagy and adhesion and promotes short-term suspension adaptation

在Vero细胞中敲低CTGF可降低自噬和细胞黏附，并促进短期悬浮适应。

期刊:Frontiers in Bioengineering and Biotechnology

影响因子:4.8

doi:10.3389/fbioe.2026.1777187

Peng, Runsheng; Jia, Renhou; Huang, Rong; Li, Muzi; Li, Xiaoyun; Zhou, Manlin; Wang, Jiamin; Qiao, Zilin; Sun, Na

HCV infection induces ubiquitin-dependent degradation of LATS1, inactivating the Hippo pathway and upregulating transcription of the CYR61 and CTGF genes

HCV感染诱导LATS1的泛素依赖性降解，使Hippo通路失活，并上调CYR61和CTGF基因的转录。

期刊:Journal of General Virology

影响因子:4.3

doi:10.1099/jgv.0.002221

Septianastiti, Maria Alethea; Matsui, Chieko; Xu, Zihan; Puspitasari, Fransisca; Adyaksa, Dewa Nyoman Murti; Deng, Lin; Abe, Takayuki; Shoji, Ikuo

Investigation into the protective effects of protocatechuic acid in bleomycin-induced pulmonary remodeling and fibrosis in rats: role of MMP-2/TIMP-1 and CTGF/NOX4 pathway

探讨原儿茶酸对博来霉素诱导的大鼠肺重塑和纤维化的保护作用：MMP-2/TIMP-1和CTGF/NOX4通路的作用

期刊:Naunyn-Schmiedebergs Archives of Pharmacology

影响因子:3.1

doi:10.1007/s00210-025-04410-6

Elgohary, Rania; Abd Elwahab, Sahar; Salama, Abeer

Author Correction: RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix

作者更正：RhoA通过调节细胞外基质中的CTGF-VEGF复合物来决定间充质干细胞的谱系命运

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-61274-3

Li, Changjun; Zhen, Gehua; Chai, Yu; Xie, Liang; Crane, Janet L; Farber, Emily; Farber, Charles R; Luo, Xianghang; Gao, Peisong; Cao, Xu; Wan, Mei

Targeting CTGF overcomes resistance to CSF1R inhibitors by preventing CAF activation in colorectal cancer

靶向CTGF可通过阻止结直肠癌中CAF的激活来克服对CSF1R抑制剂的耐药性

期刊:Cell Reports Medicine

影响因子:11.7

doi:10.1016/j.xcrm.2025.102480

Bojun Wang,Yingjue Li,Mengde Shi,Yuanyu Liao,Yuli Ruan,Shuling Han,Yue Ma,Xin Guan,Rui Yang,Tianjiao Dang,Tong Wu,Zhuo Chen,Junyi Duan,Futing Bai,Yanqiao Zhang,Chao Liu

Fusobacterium nucleatum increases CTGF expression through TLR2-YAP signaling axis in cancer-associated fibroblasts, thereby promoting colorectal cancer progression

具核梭杆菌通过TLR2-YAP信号通路增加癌相关成纤维细胞中CTGF的表达，从而促进结直肠癌的进展。

期刊:Cancer Cell International

影响因子:6

doi:10.1186/s12935-025-04023-2

Wang, Haoran; Lin, Baiqiang; Wang, Zhiyue; Yang, Jinhua; Guo, Xiao; Li, Wei; Li, Bowen; Shi, Shang; Zhou, You; Han, Rui; Wei, Yunwei; Liu, Yang

The role of CTGF and MFG-E8 in the prognosis assessment of SCAP: a study combining machine learning and nomogram analysis.

CTGF 和 MFG-E8 在 SCAP 预后评估中的作用：一项结合机器学习和列线图分析的研究

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1446415

Lin Tingting, Wan Huimin, Ming Jie, Liang Yifei, Ran Linxin, Lu Jingjing

Pancreatic CAF-Derived Autotaxin Drives Autocrine CTGF Expression to Modulate Protumorigenic Signaling

胰腺 CAF 衍生的自分泌素驱动自分泌 CTGF 表达以调节促肿瘤信号传导

期刊:Molecular Cancer Therapeutics

影响因子:5.5

doi:10.1158/1535-7163.MCT-23-0522

Volat, Fanny; Medhi, Ragini; Maggs, Lauren Z; Deken, Marcel A; Price, Alice; Andrews, Lauren; Clark, Jonathan; Taylor, Diane; Carruthers, Alan; Taylor-Smith, Ewan; Pacheco, Natalia; Rudge, Simon A; Fraser, Amy; Lopez-Clavijo, Andrea F; Sousa, Bebiana C; Johnson, Zoë; Di Conza, Giusy; van der Veen, Lars; Shah, Pritom; Sandig, Hilary; Sharpe, Hayley J; Farrow, Stuart

Role of CTGF-LRP1 in impaired healing of cesarean section incisions.

CTGF-LRP1在剖宫产切口愈合不良中的作用。

circTGFBR2(3-6) acts as an assembly platform for RNA-binding protein IGF2BP3 and TGFBR1 mRNA to enhance breast cancer cell plasticity.

circTGFBR2(3-6) 作为 RNA 结合蛋白 IGF2BP3 和 TGFBR1 mRNA 的组装平台，增强乳腺癌细胞的可塑性。

CTGF knockdown in Vero cells reduces autophagy and adhesion and promotes short-term suspension adaptation

在Vero细胞中敲低CTGF可降低自噬和细胞黏附，并促进短期悬浮适应。

HCV infection induces ubiquitin-dependent degradation of LATS1, inactivating the Hippo pathway and upregulating transcription of the CYR61 and CTGF genes

HCV感染诱导LATS1的泛素依赖性降解，使Hippo通路失活，并上调CYR61和CTGF基因的转录。

Investigation into the protective effects of protocatechuic acid in bleomycin-induced pulmonary remodeling and fibrosis in rats: role of MMP-2/TIMP-1 and CTGF/NOX4 pathway

探讨原儿茶酸对博来霉素诱导的大鼠肺重塑和纤维化的保护作用：MMP-2/TIMP-1和CTGF/NOX4通路的作用

Author Correction: RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix

作者更正：RhoA通过调节细胞外基质中的CTGF-VEGF复合物来决定间充质干细胞的谱系命运

Targeting CTGF overcomes resistance to CSF1R inhibitors by preventing CAF activation in colorectal cancer

靶向CTGF可通过阻止结直肠癌中CAF的激活来克服对CSF1R抑制剂的耐药性

Fusobacterium nucleatum increases CTGF expression through TLR2-YAP signaling axis in cancer-associated fibroblasts, thereby promoting colorectal cancer progression

具核梭杆菌通过TLR2-YAP信号通路增加癌相关成纤维细胞中CTGF的表达，从而促进结直肠癌的进展。

The role of CTGF and MFG-E8 in the prognosis assessment of SCAP: a study combining machine learning and nomogram analysis.

CTGF 和 MFG-E8 在 SCAP 预后评估中的作用：一项结合机器学习和列线图分析的研究

Pancreatic CAF-Derived Autotaxin Drives Autocrine CTGF Expression to Modulate Protumorigenic Signaling

胰腺 CAF 衍生的自分泌素驱动自分泌 CTGF 表达以调节促肿瘤信号传导