DCC相关文献与解析，生知库 | 链接生命科学的每一步

Liang Yuxin, Zeng Qiting, Xiao Maoyu, Li Pei, He Rongfang, Chen Zhangjie, Liu Jun, Cao Jingsong, Li Jun, Yin Liyang, Zhong Jing, Chen Xisha, Feng Jianbo, He Jun, Chen Xiguang, Zu Xuyu, Shen Yingying

DCC

T细胞

CD8

Glycan pairing in therapeutic IgG orchestrates Fcγ receptor engagement and ADCC: an integrated structure-function approach for thorough evaluation of Fc N-glycans as critical quality attributes

治疗性IgG中的糖链配对调控Fcγ受体结合和ADCC：一种整合结构-功能的方法，用于全面评估Fc N-糖链作为关键质量属性的作用。

期刊:MAbs

影响因子:7.3

doi:10.1080/19420862.2026.2652642

Meudt, Maximilian; Baumeister, Julia; Russell, Antoinette Cassiopeia; Dzielak, Lindsey; Hansen, Gale; Mizaikoff, Boris; Ebert, Sybille; Rosenau, Frank; Blech, Michaela; Higel, Fabian

NK cell-mediated tumor cell killing by bispecific innate cell engagers induces ADCC-mediated activation of primary human dendritic cells

双特异性固有免疫细胞衔接器介导的NK细胞杀伤肿瘤细胞可诱导ADCC介导的原代人树突状细胞活化。

期刊:Oncoimmunology

影响因子:6.3

doi:10.1080/2162402X.2026.2613561

Heger, Lukas; Kaszubowski, Tomasz; Amon, Lukas; Lehmann, Christian H K; Wingert, Susanne; Medina-Echeverz, José; Koch, Joachim; Hackstein, Holger; Purbojo, Ariawan; Hartmann, Arndt; Alexiou, Christoph; Cesnjevar, Robert; Pahl, Jens; Dudziak, Diana

Predictive value of natural killer (NK) cells in bone marrow for relapse in diffuse large B cell lymphoma: integrating antibody-dependent cell-mediated cytotoxicity (ADCC)-based immunotherapy

骨髓中自然杀伤 (NK) 细胞对弥漫性大B细胞淋巴瘤复发的预测价值：整合抗体依赖性细胞介导的细胞毒性 (ADCC) 免疫疗法

期刊:Cancer Immunology Immunotherapy

影响因子:5.1

doi:10.1007/s00262-026-04322-1

Rincón-López, Sofía; Atencio-Matos, Johelys; Pereda-Sainz, Olalla; Larreina-Pérez, Javier; Campeny-Najara, Andrea; Esteban-Figuerola, Ada; Hernandez-Perez, Montserrat; Garrastachu-Zumaran, Puy; Velasco-Ruiz, María; García-Bosque, Isabel; Rodriguez-Lefler, Carmen; Ruiz de Gaona, Estefanía; Feliu, Jesús; Cabello, Juan; Martín-Carnicero, Alfonso; García-Muñoz, Ricardo

Effects of Heat-Killed Lactobacillus acidophilus IDCC 3302 on Skin Aging Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial in Healthy Adults

热灭活嗜酸乳杆菌IDCC 3302对皮肤老化参数的影响：一项针对健康成年人的随机、双盲、安慰剂对照试验

期刊:Nutrients

影响因子:5

doi:10.3390/nu18040596

Kim, Hayoung; Bang, Won Yeong; Jeong, Kyu Ho; Jung, Young Hoon; Yang, Jungwoo; Moon, Jin Seok

An Integrated QSAR-MD-DCCM Pipeline: A Predictive Computational Platform for the Rational Design and Dynamic Functional Validation of Dual-Target Directed Ligands

集成式QSAR-MD-DCCM流程：用于双靶点导向配体合理设计和动态功能验证的预测计算平台

期刊:Pharmaceuticals

影响因子:4.8

doi:10.3390/ph19020249

Nilewar, Shrikant S; Chobe, Santosh; Dudhe, Prashik; Kumar, Perli Kranti; Lodha, Sandesh; Raut, Akansha D; Fernández-Conde, Dennys; Farhan, Mohd; Muteeb, Ghazala; Pawar, Tushar Janardan

DCC

发表日期：2026

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Targeting NKG2DLs with an ADCC enhanced fusion protein for induction of NK cell reactivity against ovarian cancer

利用ADCC增强融合蛋白靶向NKG2DLs以诱导NK细胞对卵巢癌的反应性

期刊:Journal of Ovarian Research

影响因子:4.2

doi:10.1186/s13048-025-01962-2

Hagelstein, Ilona; Wang, Kevin; Hölz, Annika; Blessing, Johanna; Lutz, Martina S

Neutralization and ADCC reveal divergent spike-subdomain targeting across SARS-CoV-2 vaccine platforms in an African cohort.

中和作用和ADCC揭示了非洲人群中不同SARS-CoV-2疫苗平台对刺突蛋白亚结构域的靶向作用存在差异。

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2025.114351

Oluka Gerald Kevin, Katende Joseph Ssebwana, Kato Laban, Ankunda Violet, Sembera Jackson, Ejou Peter, Odoch Geoffrey, Namuyanja Angella, Kaleebu Pontiano, Serwanga Jennifer

CD40L and IL-4 lymph node-associated signals protect B cells from rituximab-induced ADCC via KIR and NKG2A

CD40L 和 IL-4 淋巴结相关信号通过 KIR 和 NKG2A 保护 B 细胞免受利妥昔单抗诱导的 ADCC 损伤。

期刊:Clinical and Experimental Immunology

影响因子:3.8

doi:10.1093/cei/uxag001

Graham, Lara V; Foxall, Russell B; Ashton-Key, Margaret; Khakoo, Salim I; Sayegh, Souraya; Leandro, Maria; Reddy, Venkat R; Cragg, Mark S; Blunt, Matthew D

Frazzled/DCC directs spatial progenitor integration ensuring steady-state intestinal turnover.

Frazzled/DCC 指导空间祖细胞整合，确保肠道稳态更新。

DCC-2036 induces repolarization of TAMs to M1 type and enhances CD8(+) T cell immunity in TNBC.

DCC-2036 可诱导 TAM 向 M1 型重新极化，并增强 TNBC 中的 CD8(+) T 细胞免疫。

Glycan pairing in therapeutic IgG orchestrates Fcγ receptor engagement and ADCC: an integrated structure-function approach for thorough evaluation of Fc N-glycans as critical quality attributes

治疗性IgG中的糖链配对调控Fcγ受体结合和ADCC：一种整合结构-功能的方法，用于全面评估Fc N-糖链作为关键质量属性的作用。

NK cell-mediated tumor cell killing by bispecific innate cell engagers induces ADCC-mediated activation of primary human dendritic cells

双特异性固有免疫细胞衔接器介导的NK细胞杀伤肿瘤细胞可诱导ADCC介导的原代人树突状细胞活化。

Predictive value of natural killer (NK) cells in bone marrow for relapse in diffuse large B cell lymphoma: integrating antibody-dependent cell-mediated cytotoxicity (ADCC)-based immunotherapy

骨髓中自然杀伤 (NK) 细胞对弥漫性大B细胞淋巴瘤复发的预测价值：整合抗体依赖性细胞介导的细胞毒性 (ADCC) 免疫疗法

Effects of Heat-Killed Lactobacillus acidophilus IDCC 3302 on Skin Aging Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial in Healthy Adults

热灭活嗜酸乳杆菌IDCC 3302对皮肤老化参数的影响：一项针对健康成年人的随机、双盲、安慰剂对照试验

An Integrated QSAR-MD-DCCM Pipeline: A Predictive Computational Platform for the Rational Design and Dynamic Functional Validation of Dual-Target Directed Ligands

集成式QSAR-MD-DCCM流程：用于双靶点导向配体合理设计和动态功能验证的预测计算平台

Targeting NKG2DLs with an ADCC enhanced fusion protein for induction of NK cell reactivity against ovarian cancer

利用ADCC增强融合蛋白靶向NKG2DLs以诱导NK细胞对卵巢癌的反应性

Neutralization and ADCC reveal divergent spike-subdomain targeting across SARS-CoV-2 vaccine platforms in an African cohort.

中和作用和ADCC揭示了非洲人群中不同SARS-CoV-2疫苗平台对刺突蛋白亚结构域的靶向作用存在差异。

CD40L and IL-4 lymph node-associated signals protect B cells from rituximab-induced ADCC via KIR and NKG2A

CD40L 和 IL-4 淋巴结相关信号通过 KIR 和 NKG2A 保护 B 细胞免受利妥昔单抗诱导的 ADCC 损伤。