日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

De novo design of protein binders that target DELE1 to inhibit the mitochondrial stress response

从头设计靶向 DELE1 的蛋白质结合剂,以抑制线粒体应激反应

Yang, Rui; Zheng, Kaiyuan; Metts, McGuire; Wang, Yiluo; Yin, Danyan; Li, Kevin P; Prazmowska, Agnieszka A; Kashatus, David F; Kuhlman, Brian; Yang, Jie

DELE1 maintains muscle proteostasis to promote growth and survival in mitochondrial myopathy

DELE1 维持肌肉蛋白质稳态,从而促进线粒体肌病中的生长和存活。

Hsin-Pin Lin ,Jennifer D Petersen ,Alexandra J Gilsrud ,Angelo Madruga ,Theresa M D'Silva ,Xiaoping Huang ,Mario K Shammas ,Nicholas P Randolph ,Kory R Johnson ,Yan Li ,Drew R Jones ,Michael E Pacold ,Derek P Narendra

A mitochondrial iron-responsive pathway regulated by DELE1

DELE1调控的线粒体铁反应通路

Yusuke Sekine,Ryan Houston,Eva-Maria Eckl,Evelyn Fessler,Derek P Narendra,Lucas T Jae,Shiori Sekine

DELE1 is protective for mitochondrial cardiomyopathy

DELE1 对线粒体心肌病具有保护作用

Huynh, Helen; Zhu, Siting; Lee, Sharon; Bao, Yutong; Pang, Jing; Nguyen, Anh; Gu, Yusu; Chen, Chao; Ouyang, Kunfu; Evans, Sylvia M; Fang, Xi

Death associated protein‑3 (DAP3) and DAP3 binding cell death enhancer‑1 (DELE1) in human colorectal cancer, and their impacts on clinical outcome and chemoresistance

人类结直肠癌中的死亡相关蛋白 3 (DAP3) 和 DAP3 结合细胞死亡增强子 1 (DELE1) 及其对临床结果和化学耐药性的影响

Laijian Sui #, Jianyuan Zeng #, Huishan Zhao #, Lin Ye, Tracey A Martin, Andrew J Sanders, Fiona Ruge, Aihua Jiang, Q Ping Dou, Rachel Hargest, Xicheng Song, Wen G Jiang

DELE1 tracks perturbed protein import and processing in human mitochondria

DELE1 追踪人类线粒体中蛋白质输入和加工的异常情况

Evelyn Fessler,Luisa Krumwiede,Lucas T Jae

A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol

由DELE1协调的通路将线粒体应激传递至胞质溶胶。

Evelyn Fessler ,Eva-Maria Eckl ,Sabine Schmitt ,Igor Alves Mancilla ,Matthias F Meyer-Bender ,Monika Hanf ,Julia Philippou-Massier ,Stefan Krebs ,Hans Zischka ,Lucas T Jae