Inducible deletion of DGAT1 and 2 from microglia exacerbates neurodegeneration and endolysosomal lipid accumulation in male PS19 mice.
诱导性删除小胶质细胞中的 DGAT1 和 2 会加剧雄性 PS19 小鼠的神经退行性变和内溶酶体脂质积累。
期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2025.116841
Tabor G Travis, Litvinchuk Alexandra, Chen Yun, Allison Austin, Sun Elizabeth W, van Lengerich Bettina, Davis Sonnet S, West Elizabeth, Schlachetzki Johannes C M, Zeng Carisa, Hu Hao, Lin Peter B, Sharma Prabal, Chen Xiaoying, Parhizkar Samira, Song Sihui, Bao Xin, Senthil Lakshita, Iyer Abhirami K, You Shih Feng, Serrano Javier Remolina, Manis Melissa, Franke Emily, Cashikar Anil G, Yuede Carla M, Suh Jung H, Karch Celeste M, Folick Andrew, Koliwad Suneil K, Farese Robert V Jr, Walther Tobias, Huang Eric J, Artyomov Maxim, Glass Christopher K, Di Paolo Gilbert, Ulrich Jason D, Holtzman David M
