DJ-1相关文献与解析，生知库 | 链接生命科学的每一步

VMAT2 dysfunction impairs vesicular dopamine uptake, driving its oxidation and Î±-synuclein pathology in DJ-1-linked Parkinson's neurons.

VMAT2 功能障碍会损害囊泡多巴胺的摄取，从而导致 DJ-1 相关的帕金森神经元中多巴胺的氧化和 α-突触核蛋白病理。

Heger Leonie M, Gubinelli Francesco, Huber Andreas J, Cardona-Alberich Aida, Rovere Matteo, Matti Ulf, MÃ¼ller Stephan A, Nagaraja Sankarshana R, Jaschkowitz Lena, Schifferer Martina, Wurst Wolfgang, Lichtenthaler Stefan F, Behrends Christian, Sambandan Sivakumar, Burbulla Lena F

囊泡

DJ-1 promotes necroptosis of chondrocytes by the PTEN/PI3K-AKT signaling pathway.

DJ-1 通过 PTEN/PI3K-AKT 信号通路促进软骨细胞坏死凋亡。

期刊:Cellular and Molecular Life Sciences

影响因子:6.2

doi:10.1007/s00018-026-06122-3

Zu Xiangyu, Fu Wenhan, Tang Hao, Yang Di, Ren Yi, Li Yetian, Huang Wei, Luo Qingli, Chang Jun, Yin Zongsheng, Wu Minmin, Qin Kunpeng

Sensitive Detection of DJ-1 in Artificial Cerebrospinal Fluid Using a Portable GPTMS-Coordinated Gold Nanoparticle-Based Biosensor

利用便携式GPTMS配位金纳米粒子生物传感器对人工脑脊液中的DJ-1进行灵敏检测

期刊:Biosensors-Basel

影响因子:5.6

doi:10.3390/bios16030146

Sonuç Karaboğa, Münteha Nur

Molecular Mechanisms and Therapeutic Potential of DJ-1 in Skeletal Muscle Homeostasis and Disease

DJ-1在骨骼肌稳态和疾病中的分子机制及治疗潜力

期刊:Comprehensive Physiology

影响因子:5.2

doi:10.1002/cph4.70091

Zhang, Yue; Li, Menghuan; Xie, Xiaojing; Tian, Baokai; Bao, Zhenwei; Yi, Xuejie

DJ-1

发表日期：2026

文献求助收藏

Cellular proteostasis during mitochondrial protein import clogging requires the mitochondrial F-box protein 1 and DJ-1 homolog HSP31 in Saccharomyces cerevisiae

在酿酒酵母中，线粒体蛋白输入受阻期间的细胞蛋白质稳态需要线粒体F-box蛋白1和DJ-1同源物HSP31。

期刊:Genetics

影响因子:5.1

doi:10.1093/genetics/iyaf279

Mishra, Gargi; Wang, Xiaowen; Fitzpatrick, Eamon; Ghosh, Auyon; Chen, Xin Jie

Mechanisms of Programmed Cell Death in Sodium Iodate-Driven Retinal Degeneration and the Role of DJ-1.

碘酸钠驱动的视网膜变性中程序性细胞死亡的机制及 DJ-1 的作用。

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms27062541

Upadhyay Mala, Milliner Caroline, Bonilha Vera L

DJ-1 alleviates high glucose-induced podocyte injury via activating ERK1/2 signaling

DJ-1通过激活ERK1/2信号通路减轻高糖诱导的足细胞损伤

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0346714

Tian, Xiaochen; Li, Jing; Han, Tao; Zhang, Leisheng; Lu, Ping; Liu, Yusheng

A(2A)R antagonist IDPU facilitates the restoration of mitochondrial dynamics in 6-OHDA-induced primary mid-brain neuronal cells, via regulating p38MAPK/Parkin/DJ-1/DRP1 axis.

A(2A)R拮抗剂IDPU通过调节p38MAPK/Parkin/DJ-1/DRP1轴，促进6-OHDA诱导的原代中脑神经元细胞线粒体动力学的恢复。

期刊:Purinergic Signalling

影响因子:2.4

doi:10.1007/s11302-025-10124-4

Walecha Vaishali, Mishra Jyoti, Sophronea Tuithung, Kumari Namrata, Luthra Pratibha Mehta

Correction to: DJ-1 is dispensable for human stem cell homeostasis

更正：DJ-1 对人类干细胞稳态并非必需

期刊:Protein & Cell

影响因子:12.8

doi:10.1093/procel/pwaf034

DJ-1 inhibition reshapes tumor microenvironment and potentiates immune checkpoint inhibitors

DJ-1抑制剂可重塑肿瘤微环境并增强免疫检查点抑制剂的疗效。

VMAT2 dysfunction impairs vesicular dopamine uptake, driving its oxidation and Î±-synuclein pathology in DJ-1-linked Parkinson's neurons.

VMAT2 功能障碍会损害囊泡多巴胺的摄取，从而导致 DJ-1 相关的帕金森神经元中多巴胺的氧化和 α-突触核蛋白病理。

DJ-1 promotes necroptosis of chondrocytes by the PTEN/PI3K-AKT signaling pathway.

DJ-1 通过 PTEN/PI3K-AKT 信号通路促进软骨细胞坏死凋亡。

Sensitive Detection of DJ-1 in Artificial Cerebrospinal Fluid Using a Portable GPTMS-Coordinated Gold Nanoparticle-Based Biosensor

利用便携式GPTMS配位金纳米粒子生物传感器对人工脑脊液中的DJ-1进行灵敏检测

Molecular Mechanisms and Therapeutic Potential of DJ-1 in Skeletal Muscle Homeostasis and Disease

DJ-1在骨骼肌稳态和疾病中的分子机制及治疗潜力

Cellular proteostasis during mitochondrial protein import clogging requires the mitochondrial F-box protein 1 and DJ-1 homolog HSP31 in Saccharomyces cerevisiae

在酿酒酵母中，线粒体蛋白输入受阻期间的细胞蛋白质稳态需要线粒体F-box蛋白1和DJ-1同源物HSP31。

Mechanisms of Programmed Cell Death in Sodium Iodate-Driven Retinal Degeneration and the Role of DJ-1.

碘酸钠驱动的视网膜变性中程序性细胞死亡的机制及 DJ-1 的作用。

DJ-1 alleviates high glucose-induced podocyte injury via activating ERK1/2 signaling

DJ-1通过激活ERK1/2信号通路减轻高糖诱导的足细胞损伤

A(2A)R antagonist IDPU facilitates the restoration of mitochondrial dynamics in 6-OHDA-induced primary mid-brain neuronal cells, via regulating p38MAPK/Parkin/DJ-1/DRP1 axis.

A(2A)R拮抗剂IDPU通过调节p38MAPK/Parkin/DJ-1/DRP1轴，促进6-OHDA诱导的原代中脑神经元细胞线粒体动力学的恢复。

Correction to: DJ-1 is dispensable for human stem cell homeostasis

更正：DJ-1 对人类干细胞稳态并非必需