DMPK相关文献与解析，生知库 | 链接生命科学的每一步

In vitro and in vivo ADME of heterobifunctional degraders: a tailored approach to optimize DMPK properties of PROTACs©

异双功能降解剂的体外和体内 ADME：一种优化 PROTAC© DMPK 特性的定制方法

Maurer, Christine Katharina; Fang, Zhizhou; Schindler, Christina; Pohl, Gianna; Machrouhi-Porcher, Fouzia; Lecomte, Marc; Petersson, Carl; Duevel, Heide Marika

DMPK

发表日期：2025

文献求助收藏

Investigation on LASSBio-1971 and LASSBio-1974 Cellular Cytotoxic Mechanism and Their Comparative DMPK Profile

LASSBio-1971 和 LASSBio-1974 细胞毒性机制及其 DMPK 特征比较研究

期刊:Archiv der Pharmazie

影响因子:3.6

doi:10.1002/ardp.70151

de Moraes Junior, Manoel Oliveira; Barbosa, Gisele; da Costa, Caroline Marques Xavier; Pillpe-Meza, Raysa Magali; de Gouveia, Wesley Leandro; do Amaral, Daniel Nascimento; Gelves, Luis Gabriel Valdivieso; Laufer, Stefan; Lima, Lídia Moreira

Neonatal congenital myotonic dystrophy with DMPK gene expansion: clinical features and short-term outcomes

DMPK基因扩增的新生儿先天性肌强直营养不良：临床特征和短期预后

期刊:Frontiers in Pediatrics

影响因子:2

doi:10.3389/fped.2025.1648611

Zhao, Qian; Wang, Shupeng; Wang, Yang; Ding, Shenggang

Bleb revision and transscleral cyclophotocoagulation for congenital glaucoma patient with Turner syndrome and DMPK gene mutation: a case report

先天性青光眼合并特纳综合征和DMPK基因突变患者的滤泡修复和经巩膜睫状体光凝术：病例报告

期刊:International Journal of Ophthalmology

影响因子:1.8

doi:10.18240/ijo.2025.04.22

Guo, An-Qi; Zhang, Wei-Jia; Hong, Ying; Zhang, Chun

Characterization of DMPK and MBNL1 expression in cell models of myotonic dystrophy: a platform for drug screening

肌强直性营养不良细胞模型中DMPK和MBNL1表达的特征分析：药物筛选平台

期刊:

影响因子:

doi:10.1093/narmme/ugaf023

López-Martínez, Andrea; Martín-González, Sergio; Torres-Conde, Noemi; Alcalá-Manso, Nahia; Al-Ani, Abdullah; López de Munain, Adolfo; Bigot, Anne; Mamchaoui, Kamel; Nogales-Gadea, Gisela; Arechavala-Gomeza, Virginia

In vitro, in vivo, and in silico approaches for evaluating the preclinical DMPK profiles of ammoxetine, a novel chiral serotonin and norepinephrine reuptake inhibitor.

采用体外、体内和计算机模拟方法评估新型手性血清素和去甲肾上腺素再摄取抑制剂氨莫西汀的临床前DMPK特征。

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2024.1486856

DMPK

发表日期：2024

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Special issue devoted to the IAPC-10 Meeting: Joint World Conferences on Physico-Chemical Methods in Drug Discovery and Development and on ADMET and DMPK

本期特刊聚焦IAPC-10会议：药物发现与开发中的物理化学方法及ADMET和DMPK联合世界会议。

期刊:ADMET and DMPK

影响因子:4.3

doi:10.5599/admet.2541

Verbić, Tatjana; Mandić, Zoran

[Two cases of congenital myotonic dystrophy type 1 caused by DMPK gene variants]

【两例由DMPK基因变异引起的先天性肌强直性营养不良1型病例】

AAV-mediated DMPK silencing: A defining moment in myotonic dystrophy type 1 therapeutics

AAV介导的DMPK沉默：1型强直性肌营养不良症治疗的决定性时刻

Interrupted CTG repeats in the 37-43 units size range in the 3'UTR of DMPK are common alleles

DMPK 3'UTR 中 37-43 个单元大小范围内的 CTG 重复序列中断是常见的等位基因。

In vitro and in vivo ADME of heterobifunctional degraders: a tailored approach to optimize DMPK properties of PROTACs©

异双功能降解剂的体外和体内 ADME：一种优化 PROTAC© DMPK 特性的定制方法

Investigation on LASSBio-1971 and LASSBio-1974 Cellular Cytotoxic Mechanism and Their Comparative DMPK Profile

LASSBio-1971 和 LASSBio-1974 细胞毒性机制及其 DMPK 特征比较研究

Neonatal congenital myotonic dystrophy with DMPK gene expansion: clinical features and short-term outcomes

DMPK基因扩增的新生儿先天性肌强直营养不良：临床特征和短期预后

Bleb revision and transscleral cyclophotocoagulation for congenital glaucoma patient with Turner syndrome and DMPK gene mutation: a case report

先天性青光眼合并特纳综合征和DMPK基因突变患者的滤泡修复和经巩膜睫状体光凝术：病例报告

Characterization of DMPK and MBNL1 expression in cell models of myotonic dystrophy: a platform for drug screening

肌强直性营养不良细胞模型中DMPK和MBNL1表达的特征分析：药物筛选平台

In vitro, in vivo, and in silico approaches for evaluating the preclinical DMPK profiles of ammoxetine, a novel chiral serotonin and norepinephrine reuptake inhibitor.

采用体外、体内和计算机模拟方法评估新型手性血清素和去甲肾上腺素再摄取抑制剂氨莫西汀的临床前DMPK特征。

Special issue devoted to the IAPC-10 Meeting: Joint World Conferences on Physico-Chemical Methods in Drug Discovery and Development and on ADMET and DMPK

本期特刊聚焦IAPC-10会议：药物发现与开发中的物理化学方法及ADMET和DMPK联合世界会议。