ELL2相关文献与解析，生知库 | 链接生命科学的每一步

NELL2, a novel osteoinductive factor, regulates osteoblast differentiation and bone homeostasis through fibronectin 1/integrin-mediated FAK/AKT signaling

NELL2是一种新型骨诱导因子，它通过纤连蛋白1/整合素介导的FAK/AKT信号通路调节成骨细胞分化和骨稳态。

Yuan, Hairui; Wang, Xinyu; Du, Shuanglin; Li, Mengyue; Zhu, Endong; Zhou, Jie; Dong, Yuan; Wang, Shuang; Shan, Liying; Liu, Qian; Wang, Baoli

ELL2

NELL2 suppresses epithelial-mesenchymal transition and induces ferroptosis via notch signaling pathway in HCC

NELL2通过Notch信号通路抑制肝细胞癌中的上皮-间质转化并诱导铁死亡。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-94669-9

Liu, Shiqi; Wu, Haomin; Zhang, Pengjie; Zhou, Haonan; Wu, Di; Jin, Yifan; Yang, Hongwei; Xing, Ruilin; Wu, Yubo; Wu, Gang

NELL2- PAX7 Transcriptional Cascade Suggests Activation Mechanism for RAD52-Dependent Alternative Lengthening of Telomeres During Malignant Transformation of Malignant Peripheral Nerve Sheath Tumors: Elongation of Telomeres and Poor Survival

NELL2-PAX7转录级联提示恶性周围神经鞘瘤恶性转化过程中RAD52依赖性端粒替代延长的激活机制：端粒延长与生存率低下

期刊:Biomedicines

影响因子:3.9

doi:10.3390/biomedicines13020281.

Jungwoo Lee ,Eunji Choi ,Hyoju Kim ,Young-Joon Kim ,Seung Hyun Kim

Ewing sarcoma depends on C4orf48/NICOL, a NELL2 cofactor regulated by Hippo signaling.

尤文氏肉瘤依赖于 C4orf48/NICOL，它是 Hippo 信号通路调控的 NELL2 辅助因子。

期刊:Cellular Signalling

影响因子:3.7

doi:10.1016/j.cellsig.2025.111904

Jayabal Panneerselvam, Ma Xiuye, Chen Yidong, Yuan Yaxia, Shiio Yuzuru

Glu592 of the axon guidance receptor ROBO3 mediates a pH-dependent interaction with NELL2 ligand

轴突导向受体ROBO3的Glu592介导与NELL2配体的pH依赖性相互作用

期刊:FEBS Letters

影响因子:3

doi:10.1002/1873-3468.15054

Mizutani, Kimihiko; Toyoda, Mayuko; Ojima-Kato, Teruyo; Maturana, Andrés D; Niimi, Tomoaki

DHX38 restricts chemoresistance by regulating the alternative pre-mRNA splicing of RELL2 in pancreatic ductal adenocarcinoma

DHX38通过调控胰腺导管腺癌中RELL2的mRNA选择性剪接来限制化疗耐药性

期刊:PLoS Genetics

影响因子:3.7

doi:10.1371/journal.pgen.1010847

Li, Zeru; Qin, Cheng; Zhao, Bangbo; Wang, Yuanyang; Li, Tianyu; Zhao, Yutong; Wang, Weibin

Comprehensive Analysis of RELL2 as a Potential Biomarker Associated with Tumor Immune Infiltrating Cells in a Pan-Cancer Analysis

对RELL2作为与肿瘤免疫浸润细胞相关的潜在生物标志物进行泛癌分析的综合分析

期刊:Disease Markers

影响因子:

doi:10.1155/2022/5009512

Musha, Kadeerjiang; Ge, Xinqi; Ablikim, Nuraliya; Lu, Bing; Chen, Chen; Huang, Jianfei

Retraction of: The E2F1 Oncogene Transcriptionally Regulates NELL2 in Cancer Cells by Kim, et al. (doi: 10.1089/dna.2013.1974)

撤稿：Kim 等人的论文《E2F1 癌基因转录调控癌细胞中的 NELL2》（doi: 10.1089/dna.2013.1974）

期刊:

影响因子:

doi:10.1089/dna.2013.1974.retract

The tRNA-Derived Fragment-3017A Promotes Metastasis by Inhibiting NELL2 in Human Gastric Cancer

tRNA衍生片段-3017A通过抑制NELL2促进人胃癌转移

期刊:Frontiers in Oncology

影响因子:3.5

doi:10.3389/fonc.2020.570916

Linhao Tong,Weixu Zhang,Bicheng Qu,Fei Zhang,Zhonghua Wu,Jinxin Shi,Xiaowan Chen,Yongxi Song,Zhenning Wang

Deciphering the functions of NELL2 in tumorigenesis and beyond

揭示 NELL2 在肿瘤发生及其他过程中的功能

NELL2, a novel osteoinductive factor, regulates osteoblast differentiation and bone homeostasis through fibronectin 1/integrin-mediated FAK/AKT signaling

NELL2是一种新型骨诱导因子，它通过纤连蛋白1/整合素介导的FAK/AKT信号通路调节成骨细胞分化和骨稳态。

NELL2 suppresses epithelial-mesenchymal transition and induces ferroptosis via notch signaling pathway in HCC

NELL2通过Notch信号通路抑制肝细胞癌中的上皮-间质转化并诱导铁死亡。

NELL2- PAX7 Transcriptional Cascade Suggests Activation Mechanism for RAD52-Dependent Alternative Lengthening of Telomeres During Malignant Transformation of Malignant Peripheral Nerve Sheath Tumors: Elongation of Telomeres and Poor Survival

NELL2-PAX7转录级联提示恶性周围神经鞘瘤恶性转化过程中RAD52依赖性端粒替代延长的激活机制：端粒延长与生存率低下

Ewing sarcoma depends on C4orf48/NICOL, a NELL2 cofactor regulated by Hippo signaling.

尤文氏肉瘤依赖于 C4orf48/NICOL，它是 Hippo 信号通路调控的 NELL2 辅助因子。

Glu592 of the axon guidance receptor ROBO3 mediates a pH-dependent interaction with NELL2 ligand

轴突导向受体ROBO3的Glu592介导与NELL2配体的pH依赖性相互作用

DHX38 restricts chemoresistance by regulating the alternative pre-mRNA splicing of RELL2 in pancreatic ductal adenocarcinoma

DHX38通过调控胰腺导管腺癌中RELL2的mRNA选择性剪接来限制化疗耐药性

Comprehensive Analysis of RELL2 as a Potential Biomarker Associated with Tumor Immune Infiltrating Cells in a Pan-Cancer Analysis

对RELL2作为与肿瘤免疫浸润细胞相关的潜在生物标志物进行泛癌分析的综合分析

Retraction of: The E2F1 Oncogene Transcriptionally Regulates NELL2 in Cancer Cells by Kim, et al. (doi: 10.1089/dna.2013.1974)

撤稿：Kim 等人的论文《E2F1 癌基因转录调控癌细胞中的 NELL2》（doi: 10.1089/dna.2013.1974）

The tRNA-Derived Fragment-3017A Promotes Metastasis by Inhibiting NELL2 in Human Gastric Cancer

tRNA衍生片段-3017A通过抑制NELL2促进人胃癌转移