日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Intraperitoneal Co-Delivery of Claudin18.2×41BB and EpCAM×CD3 Bispecific Antibodies via mRNA-LNPs Synergistically Suppresses Gastric Cancer Peritoneal Metastasis Through T Cell Co-Activation.

通过 mRNA-LNP 腹腔内共递送 Claudin18.2×41BB 和 EpCAM×CD3 双特异性抗体，可协同抑制胃癌腹膜转移，其机制是通过 T 细胞共激活。

期刊:International Journal of Nanomedicine
影响因子:6.5
doi:10.2147/IJN.S577606
Che Jinze, Guo Yan Yan, Guo Lili, Liu Jinjing, Li Tong, Fei Yang
胃癌
细胞生物学
CD3
EPCAM
发表日期：2026
文献求助 收藏

EpCAM-PSMA: Potential predictors of treatment outcomes for PSMA-targeted alpha therapies in metastatic castration-resistant prostate cancer

EpCAM-PSMA：转移性去势抵抗性前列腺癌中PSMA靶向α疗法治疗结果的潜在预测因子

期刊:Molecular Therapy Oncology
影响因子:4.5
doi:10.1016/j.omton.2026.201143
Gábor Bakos,Ulrike Bauder-Wüst,Jonathan Landry,Mareike Roscher,Beáta Ramasz,Frank Bruchertseifer,Alfred Morgenstern,Clemens Kratochwil,Vladimír Beneš,Martina Benešová-Schäfer
前列腺癌
肿瘤
EPCAM
发表日期：2026
文献求助 收藏

Preliminary assessment of biodistribution and targeting of the fluorescent molecular probe Cy7-SYL3C in an EpCAM-positive colorectal cancer mouse model.

在EpCAM阳性结直肠癌小鼠模型中对荧光分子探针Cy7-SYL3C的生物分布和靶向性进行初步评估。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-37787-2
Li Yiwen, Li Min, Li Pinghui, Huang Zhidie, Liu Xiang, Duan Xiaoyan, Li Jianbo
肠癌
Mouse
肿瘤
EPCAM
发表日期：2026
文献求助 收藏

RNA-Seq analysis reveals regulatory networks driven by EpCAM overexpression in esophageal adenocarcinoma cells.

RNA-Seq 分析揭示了食管腺癌细胞中 EpCAM 过表达驱动的调控网络。

期刊:PeerJ
影响因子:2.4
doi:10.7717/peerj.20877
Mohtar M Aiman, Nasir Siti Nurmi, Abd Razak Zuraini, Mohamad Said Hanif Zulkhairi, Zahari Syazalina, Syafruddin Saiful Effendi
细胞生物学
EPCAM
发表日期：2026
文献求助 收藏

Double Trouble: EPCAM Exon 9 Deletion in Lynch Syndrome Leading to Dual Primary Tumors

双重麻烦：林奇综合征中EPCAM外显子9缺失导致双原发肿瘤

期刊:Cureus Journal of Medical Science
影响因子:1.3
doi:10.7759/cureus.105528
Kalfoutzou, Areti; Rapti, Cleopatra; Almpanis, Zannis; Bagiokou, Eleftheria; Kalakos, Nikolaos; Lagopoulou, Vasiliki; Kolintzikis, Vasileios; Oikonomakis, Aristeidis; Chaleplidis, Nikolaos; Ramfidis, Vasileios
EPCAM
肿瘤
肿瘤免疫
发表日期：2026
文献求助 收藏

Preclinical development and a phase 1 trial of IMC001, an EpCAM-targeted CAR-T cell therapy, in patients with advanced gastric cancer

IMC001（一种靶向EpCAM的CAR-T细胞疗法）在晚期胃癌患者中的临床前开发和I期临床试验

期刊:Molecular Therapy
影响因子:12.1
doi:10.1016/j.ymthe.2025.08.014
Weijia Fang ，Zhengmao Lu ，Jingyu Ge ，Shuangshuang Zhang ，Rui Zheng ，Weiwei Yin ，Ruidong Hao ，Minmin Sun ，Tianhang Luo
肿瘤
胃癌
巨噬细胞
EPCAM
T细胞
发表日期：2025
文献求助 收藏

EpCAM activates the ERK-EGR1 signaling axis and promotes TNF-α-induced the progression of anaplastic thyroid cancer.

EpCAM 激活 ERK-EGR1 信号轴，促进 TNF-α 诱导的间变性甲状腺癌的进展。

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-025-07575-z
Lee Chi-Chiu, Su Yi-Jen, Panda Sushree Shankar, Chiu Chiung-Yi, Wu Chung-Hsuan, Lu Tsai-Ming, Li Pi-Chun, Huang Yen-Lin, Hong Ruey-Long, Hung Shao-Hsi, Yee Cassian, Lai Stephen Y, Wu Han-Chung
甲状腺癌
信号转导
TNF
EGR1
TNF-α
EPCAM
MAPK/ERK
发表日期：2025
文献求助 收藏

A EPCAM Pathogenic Variant in Familial Lynch Syndrome-Associated Colon Cancer: Insights into Genetic Basis and Tumor Microenvironment Characteristics

家族性林奇综合征相关结肠癌中的EPCAM致病变异：遗传基础和肿瘤微环境特征的深入研究

期刊:Phenomics
影响因子:6.2
doi:10.1007/s43657-024-00202-9
Wang, Sumeng; Zhang, Ke; Cheng, Yifei; Liu, Lingxiang; Du, Mulong
肿瘤
肠癌
EPCAM
肿瘤免疫
肿瘤微环境
发表日期：2025
文献求助 收藏

Quantitative HER2 profiling on circulating tumor cells using an EpCAM-independent platform in metastatic breast cancer.

利用不依赖于EpCAM的平台对转移性乳腺癌的循环肿瘤细胞进行HER2定量分析。

期刊:Cancer Cell International
影响因子:6
doi:10.1186/s12935-025-04036-x
Bayou Nadia, Henretta Sarah, Munoz-Arcos Laura, Molteni Elisabetta, Gianni Caterina, Serafini Mara Serena, Nicolò Eleonora, Pontolillo Letizia, Pasto Brenno, Gaudio Hunter Andrew, Manai Maroua, Afghan Muhammad Maaz Khan, Manohar Jyothi, Elemento Olivier, Andreopoulou Eleni, Cristofanilli Massimo, Reduzzi Carolina
乳腺癌
细胞生物学
肿瘤细胞
HER2
EPCAM
发表日期：2025
文献求助 收藏

A single-sEV analysis identifies plasma EPCAM(+) sEVs as a biomarker for early diagnosis and monitoring postoperative remission of thyroid cancer

单细胞外囊泡（sEV）分析表明，血浆中EPCAM(+) sEV可作为甲状腺癌早期诊断和术后缓解监测的生物标志物。

期刊:Extracellular Vesicles and Circulating Nucleic Acids
影响因子:4.8
doi:10.20517/evcna.2025.93
Yu, Simin; Luo, Yuting; Dang, Tianfeng; Peng, Congli; Gan, Qing; Liang, Yuxuan; Yu, Jieqing; Long, Ping; Zhou, Wensheng; Dai, Daofeng
细胞生物学
EPCAM
肿瘤免疫
囊泡
肿瘤
单细胞
甲状腺癌
免疫/内分泌
发表日期：2025
文献求助 收藏