FFAR2相关文献与解析，生知库 | 链接生命科学的每一步

Short-chain fatty acids butyrate and acetate limit Zika virus replication and associated ocular manifestations via the G-protein coupled receptor 43/FFAR2

短链脂肪酸丁酸和乙酸通过G蛋白偶联受体43/FFAR2限制寨卡病毒的复制及其相关的眼部症状。

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/jvi.01826-25

Deshmukh, Nikhil; Kumar, Prince; Kumar, Lal Krishan; Balendiran, Vaishnavi; Singh, Pawan Kumar

Gut Microbiota-Derived Lipopolysaccharides and Short-Chain Fatty Acids Regulate Immune Responses via FFAR2/FFAR3 in Lung Ischemia-Reperfusion Injury

肠道菌群来源的脂多糖和短链脂肪酸通过FFAR2/FFAR3调节肺缺血再灌注损伤中的免疫反应

期刊:Annals of the New York Academy of Sciences

影响因子:4.8

doi:10.1111/nyas.70043

Maruyama, Daisuke; Doan, Thien N M; Tian, Xiaoli; Chaki, Tomohiro; Yeh, Jade J; Layden, Brian T; Prakash, Arun

Liqi Yangyin formula ameliorates CUMS-induced depression and comorbid constipation via ACE/FFAR2 modulation of the microbiota-gut-brain axis.

利气养阴方通过ACE/FFAR2调节肠道菌群-肠-脑轴，改善慢性不可预测性应激障碍引起的抑郁症和合并便秘。

期刊:Frontiers in Cellular and Infection Microbiology

影响因子:4.8

doi:10.3389/fcimb.2025.1692110

Xu Lianjie, Ong Shun Seng, Deng Xiaoyue, Qian Yunzhi, Lu Hai, Song Yang, Wang Yang, Xu Tianshu

Amelioration of Central Nervous System Autoimmunity Through FFAR2 Agonism Is Associated With Changes in Gut Microbiota

FFAR2激动剂改善中枢神经系统自身免疫与肠道菌群变化相关

期刊:Brain and Behavior

影响因子:2.7

doi:10.1002/brb3.70350

Jevtić, Bojan; Stegnjaić, Goran; Stanisavljević, Suzana; Lazarević, Milica; Nikolić, Filip; Fraser, Graeme L; Miljković, Đorđe; Dimitrijević, Mirjana

Gut microbial metabolites butyrate and acetate limit Zika virus replication and associated ocular manifestations via the G-protein coupled receptor 43/FFAR2

肠道微生物代谢产物丁酸盐和乙酸盐通过G蛋白偶联受体43/FFAR2限制寨卡病毒复制及其相关的眼部症状。

期刊:

影响因子:

doi:10.1101/2025.07.15.664962

Deshmukh, Nikhil; Kumar, Prince; Kumar, Lal Krishan; Balendiran, Vaishnavi; Singh, Pawan Kumar

Dietary Fiber Improves Somatosensory Function in Western Diet-Fed Mice by Remodeling Adipose Immune Cells via FFAR2 Signaling.

膳食纤维通过 FFAR2 信号通路重塑脂肪免疫细胞，从而改善喂食高脂饮食小鼠的体感功能。

期刊:

影响因子:

doi:10.21203/rs.3.rs-7868021/v1

Gavini Chaitanya, Raux Laetitia, LabouÃ¨be GwenaÃ«l, Gornick Emily, Hugh Sarah Mc, Elshareif Nadia, Calcutt Nigel, Summa Pietro Di, Gorostidi FranÃ§ois, Vonaesch Pascale, Mansuy-Aubert Virginie

Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3

短链脂肪酸受体FFAR2/3的分子识别和激活机制

期刊:Cell Research

影响因子:25.9

doi:10.1038/s41422-023-00914-z

Li, Fahui; Tai, Linhua; Sun, Xiaoyu; Lv, Zhenyu; Tang, Wenqin; Wang, Tianxin; Zhao, Ziyi; Gong, Daohong; Ma, Shaohua; Tang, Shichen; Gu, Quanchang; Zhu, Xiaolei; Yu, Minling; Liu, Xiaohong; Wang, Jiangyun

Gut microbiota-derived acetate attenuates lung injury induced by influenza infection via protecting airway tight junctions

肠道微生物衍生的醋酸盐通过保护气道紧密连接减轻流感感染引起的肺损伤

期刊:Journal of Translational Medicine

影响因子:6.1

doi:10.1186/s12967-024-05376-4

Lei Hu #, Li Sun #, Chun Yang, Da-Wei Zhang, Yuan-Yuan Wei, Ming-Ming Yang, Hui-Mei Wu, Guang-He Fei

Bacillus coagulans restores pathogen-induced intestinal dysfunction via acetate-FFAR2-NF-κB-MLCK-MLC axis in Apostichopus japonicus

凝结芽孢杆菌通过乙酸盐-FFAR2-NF-κB-MLCK-MLC轴修复日本刺参中病原体引起的肠道功能障碍

期刊:mSystems

影响因子:4.6

doi:10.1128/msystems.00602-24

Song, Mingshan; Zhang, Shanshan; Zhang, Zhen; Guo, Liyuan; Liang, Weikang; Li, Chenghua; Wang, Zhonghua

Lung dysbiosis disrupts an FFAR2-mediated innate immune circuit against Klebsiella pneumoniae

肺部菌群失调会破坏FFAR2介导的针对肺炎克雷伯菌的先天免疫回路

Short-chain fatty acids butyrate and acetate limit Zika virus replication and associated ocular manifestations via the G-protein coupled receptor 43/FFAR2

短链脂肪酸丁酸和乙酸通过G蛋白偶联受体43/FFAR2限制寨卡病毒的复制及其相关的眼部症状。

Gut Microbiota-Derived Lipopolysaccharides and Short-Chain Fatty Acids Regulate Immune Responses via FFAR2/FFAR3 in Lung Ischemia-Reperfusion Injury

肠道菌群来源的脂多糖和短链脂肪酸通过FFAR2/FFAR3调节肺缺血再灌注损伤中的免疫反应

Liqi Yangyin formula ameliorates CUMS-induced depression and comorbid constipation via ACE/FFAR2 modulation of the microbiota-gut-brain axis.

利气养阴方通过ACE/FFAR2调节肠道菌群-肠-脑轴，改善慢性不可预测性应激障碍引起的抑郁症和合并便秘。

Amelioration of Central Nervous System Autoimmunity Through FFAR2 Agonism Is Associated With Changes in Gut Microbiota

FFAR2激动剂改善中枢神经系统自身免疫与肠道菌群变化相关

Gut microbial metabolites butyrate and acetate limit Zika virus replication and associated ocular manifestations via the G-protein coupled receptor 43/FFAR2

肠道微生物代谢产物丁酸盐和乙酸盐通过G蛋白偶联受体43/FFAR2限制寨卡病毒复制及其相关的眼部症状。

Dietary Fiber Improves Somatosensory Function in Western Diet-Fed Mice by Remodeling Adipose Immune Cells via FFAR2 Signaling.

膳食纤维通过 FFAR2 信号通路重塑脂肪免疫细胞，从而改善喂食高脂饮食小鼠的体感功能。

Molecular recognition and activation mechanism of short-chain fatty acid receptors FFAR2/3

短链脂肪酸受体FFAR2/3的分子识别和激活机制

Gut microbiota-derived acetate attenuates lung injury induced by influenza infection via protecting airway tight junctions

肠道微生物衍生的醋酸盐通过保护气道紧密连接减轻流感感染引起的肺损伤

Bacillus coagulans restores pathogen-induced intestinal dysfunction via acetate-FFAR2-NF-κB-MLCK-MLC axis in Apostichopus japonicus

凝结芽孢杆菌通过乙酸盐-FFAR2-NF-κB-MLCK-MLC轴修复日本刺参中病原体引起的肠道功能障碍