日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Excess FGFR3 signaling in achondroplasia disrupts turnover of resting zone chondrocytes via CREB signaling

软骨发育不全中FGFR3信号过度激活会通过CREB信号通路破坏静止区软骨细胞的更新。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69507-9
Horike, Nanao; Oura, Seiya; Koyamatsu, Saeko; Tanaka, Noriko; Iimori, Yuki; Fujita, Kaori; Nemoto, Takahiro; Ikawa, Masahito; Tsumaki, Noriyuki
FGFR3
发育与干细胞
信号转导
CREB
细胞生物学
发表日期：2026
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Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

FGFR3自身抗体在小纤维神经病变中的致病作用

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202511413
Salih, Lyuba Y; Dumaire, Nicolas L A; Gieré, Clémence; Vest, Erin; Alkhateeb, Haya; Moritz, Christian P; Tholance, Yannick; Camdessanché, Jean-Philippe; Antoine, Jean-Christophe; Honnorat, Jérôme; Kafaie, Jafar; François-Moutal, Liberty; Moutal, Aubin
FGFR3
免疫/内分泌
发表日期：2026
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A Novel FGFR3-Targeting Antibody-Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS-STING Pathway in Bladder Cancer.

一种新型的FGFR3靶向抗体-药物偶联物通过cGAS-STING通路诱导膀胱癌细胞凋亡。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202509933
膀胱癌
细胞生物学
信号转导
肿瘤
表观遗传
CGAS
FGFR3
STING
Apoptosis
凋亡
发表日期：2026
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Dabogratinib (TYRA-300), an FGFR3 Isoform-Selective Inhibitor: Preclinical and Initial Clinical Evidence of Antitumor Activity

Dabogratinib (TYRA-300)，一种FGFR3亚型选择性抑制剂：抗肿瘤活性的临床前和初步临床证据

期刊:Molecular Cancer Therapeutics
影响因子:5.5
doi:10.1158/1535-7163.MCT-25-0652
Starrett, Jacqueline H; Allen, Eric L; Neal, Melissa; Iyer, Samhita; Ye, Qing; Hudkins, Robert L; Degaonkar, Viraj; Lihou, Christine; Swanson, Ronald V; Boni, Valentina; Fuentes-Antrás, Jesús; Pobel, Cedric; Loriot, Yohann; Zalutskaya, Alena; Goluboff, Erik
FGFR3
肿瘤
肿瘤免疫
发表日期：2026
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SREBP2-RAB11A-ZDHHC20 axis orchestrates FGFR3 palmitoylation and membrane retention to drive bladder cancer progression.

SREBP2-RAB11A-ZDHHC20 轴协调 FGFR3 棕榈酰化和膜滞留，从而驱动膀胱癌进展。

期刊:Cellular Oncology
影响因子:4.8
doi:10.1007/s13402-026-01163-z
膀胱癌
肿瘤
DHH
EBP
FGFR3
Rab11
发表日期：2026
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From a Polymorphous Low-Grade Neuroepithelial Tumor to a Glioblastoma in an Adult Patient with FGFR3-TACC3 Fusion: A Case Report and Literature Review of the Molecular Profile

从多形性低级别神经上皮肿瘤到成人患者胶质母细胞瘤的FGFR3-TACC3融合基因病例报告及分子谱文献回顾

期刊:Current Oncology
影响因子:3.4
doi:10.3390/curroncol33030165
Gurrieri, Lorena; Riva, Nada; Tomassini, Alessia; Ghigi, Giulia; Naccarato, Maurizio; Cenni, Patrizia; Bartolini, Daniela; Cavatorta, Chiara; Tosatto, Luigino; Dall'Agata, Monia; Ridolfi, Laura
FGFR3
细胞生物学
肿瘤
肿瘤免疫
发表日期：2026
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FGFR3-TACC3 fusion as a potential primary resistance mechanism to EGFR-TKI in lung adenocarcinoma harboring co-driven mutations: a case report

FGFR3-TACC3融合基因作为携带共驱动突变的肺腺癌中EGFR-TKI潜在原发性耐药机制：病例报告

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2026.1780493
Wang, Xiuwen; Qiu, Liwen; Liang, Jizhen; Liu, Fei; Ma, Xiaoxue; Yang, Pan
FGFR3
肿瘤
肿瘤免疫
EGF
EGFR
发表日期：2026
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Simultaneous Establishment of Autologous Colorectal Cancer and Mesothelial Stromal Cell Lines from Malignant Ascites Reveals a Mesothelial-Stromal FGFR3 Axis as a Potential Vulnerability in Peritoneal Metastasis

同时建立自体结直肠癌细胞系和恶性腹水中的间皮基质细胞系，揭示间皮-基质FGFR3轴是腹膜转移的潜在脆弱性

期刊:Cancer Medicine
影响因子:3.1
doi:10.1002/cam4.71804
Fukui, Yasuhiro; Kasashima, Hiroaki; Wang, Zizhou; Omori, Iguru; Kusunoki, Yukina; Echizen, Kanae; Nonaka, Yoshiki; Seki, Yuki; Kuroda, Kenji; Miki, Yuichiro; Yoshii, Mami; Fukuoka, Tatsunari; Tamura, Tatsuro; Shibutani, Masatsune; Toyokawa, Takahiro; Muta, Yu; Nakanishi, Yuki; Yashiro, Masakazu; Ohtani, Naoko; Maeda, Kiyoshi
基质细胞
肿瘤
肠癌
细胞生物学
FGFR3
肿瘤免疫
发表日期：2026
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A case of thymic carcinoma harboring an FGFR3 S249C mutation with durable disease control on lenvatinib

一例携带 FGFR3 S249C 突变的胸腺癌患者，使用乐伐替尼治疗后病情得到持久控制。

期刊:International Cancer Conference Journal
影响因子:0.5
doi:10.1007/s13691-025-00836-0
Bando, Noriko; Ogino, Hirokazu; Murakami, Kojin; Wadatsu, Masami; Tsukazaki, Yuki; Yabuki, Yohei; Kajimoto, Tatsuya; Matsumoto, Rikako; Harada, Saki; Morita, Yutaka; Ozaki, Ryohiko; Mitsuhashi, Atsushi; Sato, Seidai; Sakaguchi, Satoshi; Hanibuchi, Masaki; Nishioka, Yasuhiko
FGFR3
肿瘤
肿瘤免疫
发表日期：2026
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FGFR3-induced Y158 PARP1 phosphorylation promotes PARP inhibitor resistance via BRG1/MRE11-mediated DNA repair in breast cancer models

在乳腺癌模型中，FGFR3诱导的Y158 PARP1磷酸化通过BRG1/MRE11介导的DNA修复促进PARP抑制剂耐药性

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI173757
Chen, Mei-Kuang; Yamaguchi, Hirohito; Gao, Yuan; Xia, Weiya; Chang, Jeffrey T; Hsiao, Yu-Chun; Shegute, Tewodros W; Lin, Zong-Shin; Wu, Chen-Shiou; Wang, Yu-Han; Litton, Jennifer K; Ding, Qingqing; Wei, Yongkun; Chu, Yu-Yi; Meric-Bernstam, Funda; Piwnica-Worms, Helen; Arun, Banu; Rodon Ahnert, Jordi; Liu, Jinsong; Yao, Jun; Chang, Wei-Chao; Wang, Hung-Ling; Tapia, Coya; Albarracin, Constance T; Keyomarsi, Khandan; Wang, Shao-Chun; Wang, Ying-Nai; Hortobagyi, Gabriel N; Lin, Chunru; Yang, Liuqing; Yu, Dihua; Hung, Mien-Chie
FGFR3
肿瘤
PARP1
肿瘤免疫
信号转导
乳腺癌
PARP
磷酸化
发表日期：2025
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