GALT相关文献与解析，生知库 | 链接生命科学的每一步

Comprehensive analysis of COLGALT1 in tumor microenvironment regulation and prognosis of clear cell renal cell carcinoma

对 COLGALT1 在肿瘤微环境调控和透明细胞肾细胞癌预后中的作用进行综合分析

期刊:Clinical and Experimental Medicine

影响因子:3.5

doi:10.1007/s10238-026-02041-6

Guo, Yicheng; Wang, Bin; Ding, Guixin; Zhang, Yanwei; Wang, Yini; Ma, Xiaohong; Wu, Jitao

The Gb3-synthase A4GALT is an epigenetically regulated driver of tumor invasiveness in gastrointestinal cancer

Gb3合成酶A4GALT是胃肠道肿瘤侵袭性的表观遗传调控驱动因子

期刊:BMC Cancer

影响因子:3.4

doi:10.1186/s12885-026-15600-7

Hirsch, Noah-David; Perl, Markus; Holzinger, Simon; Barz, Christoph; Enßle, Stefan; Johannes, Widya; Conrad, Anja; Unterholzner, Jonas J; Obermeier, Viktoria; Tschurtschenthaler, Markus; Johannes, Ludger; Janssen, Klaus-Peter

TFAP2A transcriptionally regulates B3GALT2 to affect gouty arthritis progression through pyroptosis: a study based on machine learning and multi-omics integration analysis.

TFAP2A 通过转录调控 B3GALT2 来影响痛风性关节炎的进展，其机制是通过细胞焦亡：一项基于机器学习和多组学整合分析的研究。

期刊:Journal of Orthopaedic Surgery and Research

影响因子:2.8

doi:10.1186/s13018-026-06696-5

Han Hui-Li, Cheng Zeng-Yu, Meng Qing-Liang, Du Xu-Zhao

Spontaneous atraumatic pediatric basal ganglia hemorrhage in the setting of COLGALT1-related collagenopathy: illustrative case

COLGALT1相关胶原病背景下的自发性非创伤性儿童基底节出血：病例报告

期刊:

影响因子:

doi:10.3171/CASE251029

Chaisson, Jacob M; Darden, Drake L; Adesina, Adeleso E; Guillen Arguello, Roboan; Haastrup, Mary O; Ponce Mejia, Lucido; Roberts, Oritsejolomi

Molecular structure and enzymatic mechanism of the human collagen hydroxylysine galactosyltransferase GLT25D1/COLGALT1

人胶原羟赖氨酸半乳糖基转移酶 GLT25D1/COLGALT1 的分子结构和酶促机制

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-59017-5

De Marco, Matteo; Rai, Sristi Raj; Scietti, Luigi; Mattoteia, Daiana; Liberi, Stefano; Moroni, Elisabetta; Pinnola, Alberta; Vetrano, Alice; Iacobucci, Claudio; Santambrogio, Carlo; Colombo, Giorgio; Forneris, Federico

The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma

O-糖基转移酶C1GALT1促进EWSR1::FLI1表达，是尤文氏肉瘤的治疗靶点。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-025-56632-0

Shahid Banday ,Alok K Mishra ,Romana Rashid ,Tianyi Ye ,Amjad Ali ,Junhui Li ,Jason T Yustein ,Michelle A Kelliher ,Lihua Julie Zhu ,Sara K Deibler ,Sunil K Malonia ,Michael R Green

EGFR TKIs suppress MUC1 glycosylation through the PI3K/AKT/SP1/C1GALT1 pathway to enhance TnMUC1 CAR-T efficacy in EGFR-mutant NSCLC

EGFR TKIs通过PI3K/AKT/SP1/C1GALT1通路抑制MUC1糖基化，从而增强TnMUC1 CAR-T细胞在EGFR突变型非小细胞肺癌中的疗效。

期刊:Cell Reports Medicine

影响因子:11.7

doi:10.1016/j.xcrm.2025.102199

Ziwei Zhou ，Si Chen ，Jianli Zhao ，Xin Du ，Haibin Yin ，Chao Zhou ，Hai Hu ，Yunfang Yu ，Yinghua Zhu ，Herui Yao

Correction: Novel post-translational modification learning signature reveals B4GALT2 as an immune exclusion regulator in lung adenocarcinoma

更正：新型翻译后修饰学习特征揭示B4GALT2是肺腺癌中的免疫排斥调节因子

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.6

doi:10.1136/jitc-2024-010787corr1

B4GALT5 inhibits CD8+ T-cell response by downregulating MHC-I level through ERAD pathway in PDAC

B4GALT5通过ERAD途径下调MHC-I水平，从而抑制PDAC中的CD8+ T细胞反应。

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.3

doi:10.1136/jitc-2024-010908

Xin Xing #,Shi-Qi Yin #,Xia-Qing Li #,Hui Li #,Hong-Tai Ma,Aziguli Tulamaiti,Shu-Yu Xiao,Yu-Tong Liu,Hao Zhang,Zhigang Zhang,Yan-Miao Huo,Xiao-Mei Yang,Yan Yang,Xue-Li Zhang

B4GALT1 deficiency attenuates steatohepatitis by regulating the PPARÎ³/ACSL4 axis.

B4GALT1 缺乏通过调节 PPARα/ACSL4 轴来减轻脂肪性肝炎。

Comprehensive analysis of COLGALT1 in tumor microenvironment regulation and prognosis of clear cell renal cell carcinoma

对 COLGALT1 在肿瘤微环境调控和透明细胞肾细胞癌预后中的作用进行综合分析

The Gb3-synthase A4GALT is an epigenetically regulated driver of tumor invasiveness in gastrointestinal cancer

Gb3合成酶A4GALT是胃肠道肿瘤侵袭性的表观遗传调控驱动因子

TFAP2A transcriptionally regulates B3GALT2 to affect gouty arthritis progression through pyroptosis: a study based on machine learning and multi-omics integration analysis.

TFAP2A 通过转录调控 B3GALT2 来影响痛风性关节炎的进展，其机制是通过细胞焦亡：一项基于机器学习和多组学整合分析的研究。

Spontaneous atraumatic pediatric basal ganglia hemorrhage in the setting of COLGALT1-related collagenopathy: illustrative case

COLGALT1相关胶原病背景下的自发性非创伤性儿童基底节出血：病例报告

Molecular structure and enzymatic mechanism of the human collagen hydroxylysine galactosyltransferase GLT25D1/COLGALT1

人胶原羟赖氨酸半乳糖基转移酶 GLT25D1/COLGALT1 的分子结构和酶促机制

The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma

O-糖基转移酶C1GALT1促进EWSR1::FLI1表达，是尤文氏肉瘤的治疗靶点。

EGFR TKIs suppress MUC1 glycosylation through the PI3K/AKT/SP1/C1GALT1 pathway to enhance TnMUC1 CAR-T efficacy in EGFR-mutant NSCLC

EGFR TKIs通过PI3K/AKT/SP1/C1GALT1通路抑制MUC1糖基化，从而增强TnMUC1 CAR-T细胞在EGFR突变型非小细胞肺癌中的疗效。

Correction: Novel post-translational modification learning signature reveals B4GALT2 as an immune exclusion regulator in lung adenocarcinoma

更正：新型翻译后修饰学习特征揭示B4GALT2是肺腺癌中的免疫排斥调节因子

B4GALT5 inhibits CD8+ T-cell response by downregulating MHC-I level through ERAD pathway in PDAC

B4GALT5通过ERAD途径下调MHC-I水平，从而抑制PDAC中的CD8+ T细胞反应。