HEXIM1相关文献与解析，生知库 | 链接生命科学的每一步

HEXIM1/P-TEFb complex controls RNA polymerase II pause release and immediate early gene induction following neuronal depolarization

HEXIM1/P-TEFb复合物控制RNA聚合酶II暂停解除和神经元去极化后的早期基因诱导

doi:10.1016/j.jbc.2026.111325

Htet, Myo; Estay-Olmos, Camila; Hu, Lan; Wu, Yiyang; Powers, Brian E; Campbell, Clorissa D; Rameshwar, Aishwarya; Ahmed, Mohamed R; Hohman, Timothy J; Wang, Yanling; Schneider, Julie A; Bennett, David A; Menon, Vilas; De Jager, Philip L; Kaas, Garrett A; Colbran, Roger J; Greer, Celeste B

HEXIM1 is an essential transcription regulator during human erythropoiesis

HEXIM1是人类红细胞生成过程中一种重要的转录调节因子。

期刊:Blood

影响因子:23.1

doi:10.1182/blood.2022019495

Lv, Xiurui; Murphy, Kristin; Murphy, Zachary; Getman, Michael; Rahman, Nabil; Nakamura, Yukio; Blanc, Lionel; Gallagher, Patrick G; Palis, James; Mohandas, Narla; Steiner, Laurie A

Erratum to "Tip110 expression facilitates the release of HEXIM1 and pTEFb from the 7SK ribonucleoprotein complex involving regulation of the intracellular redox level"

更正：“Tip110 表达促进 HEXIM1 和 pTEFb 从 7SK 核糖核蛋白复合物中释放，涉及细胞内氧化还原水平的调节”

期刊:Aging and Disease

影响因子:6.9

doi:10.14336/AD.2023.0504

Liu, Ying; Li, Lu; Timani, Khalid; White, Carl; He, Johnny J

Overexpression Bombyx mori HEXIM1 Facilitates Immune Escape of Bombyx mori Nucleopolyhedrovirus by Suppressing BmRelish-Driven Immune Responses

家蚕HEXIM1的过表达通过抑制BmRelish驱动的免疫反应促进家蚕核多角体病毒的免疫逃逸

期刊:Viruses-Basel

影响因子:3.5

doi:10.3390/v14122636

Chen, Guanping; Li, Yuedong; Kong, Xiangshuo; Zhao, Shudi; Li, Jiale; Wu, Xiaofeng

Tip110 Expression Facilitates the Release of HEXIM1 and pTEFb from the 7SK Ribonucleoprotein Complex Involving Regulation of the Intracellular Redox Level

Tip110 的表达促进 HEXIM1 和 pTEFb 从 7SK 核糖核蛋白复合物中释放，从而调节细胞内氧化还原水平。

期刊:Aging and Disease

影响因子:6.9

doi:10.14336/AD.2021.0528

Liu, Ying; Li, Lu; Timani, Khalid; White, Carl; He, Johnny J

CSB-Dependent Cyclin-Dependent Kinase 9 Degradation and RNA Polymerase II Phosphorylation during Transcription-Coupled Repair

转录偶联修复过程中 CSB 依赖的细胞周期蛋白依赖性激酶 9 降解和 RNA 聚合酶 II 磷酸化

期刊:Molecular and Cellular Biology

影响因子:3.2

doi:10.1128/MCB.00225-18

Lise-Marie Donnio, Anna Lagarou, Gabrielle Sueur, Pierre-Olivier Mari, Giuseppina Giglia-Mari

HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb.

HEXIM1 在细胞核内的扩散受其与 7SK 和 P-TEFb 相互作用的调控。

期刊:Biophysical Journal

影响因子:3.1

doi:10.1016/j.bpj.2019.09.019

The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations

增强型R环是高危剪接因子突变诱发骨髓增生异常综合征的统一机制

期刊:Molecular Cell

影响因子:14.5

doi:10.1016/j.molcel.2017.12.029

Liang Chen ,Jia-Yu Chen ,Yi-Jou Huang ,Ying Gu ,Jinsong Qiu ,Hao Qian ,Changwei Shao ,Xuan Zhang ,Jing Hu ,Hairi Li ,Shunmin He ,Yu Zhou ,Omar Abdel-Wahab ,Dong-Er Zhang ,Xiang-Dong Fu

发表日期：2018

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SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription

SIRT7 依赖的 CDK9 去乙酰化激活 RNA 聚合酶 II 转录

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkx053

Maximilian F Blank, Sifan Chen, Fabian Poetz, Martina Schnölzer, Renate Voit, Ingrid Grummt

HEXIM1 inter-monomer autoinhibition governs 7SK RNA binding specificity and P-TEFb inactivation

HEXIM1单体间的自身抑制控制着7SK RNA的结合特异性和P-TEFb的失活。

HEXIM1/P-TEFb complex controls RNA polymerase II pause release and immediate early gene induction following neuronal depolarization

HEXIM1/P-TEFb复合物控制RNA聚合酶II暂停解除和神经元去极化后的早期基因诱导

HEXIM1 is an essential transcription regulator during human erythropoiesis

HEXIM1是人类红细胞生成过程中一种重要的转录调节因子。

Erratum to "Tip110 expression facilitates the release of HEXIM1 and pTEFb from the 7SK ribonucleoprotein complex involving regulation of the intracellular redox level"

更正：“Tip110 表达促进 HEXIM1 和 pTEFb 从 7SK 核糖核蛋白复合物中释放，涉及细胞内氧化还原水平的调节”

Overexpression Bombyx mori HEXIM1 Facilitates Immune Escape of Bombyx mori Nucleopolyhedrovirus by Suppressing BmRelish-Driven Immune Responses

家蚕HEXIM1的过表达通过抑制BmRelish驱动的免疫反应促进家蚕核多角体病毒的免疫逃逸

Tip110 Expression Facilitates the Release of HEXIM1 and pTEFb from the 7SK Ribonucleoprotein Complex Involving Regulation of the Intracellular Redox Level

Tip110 的表达促进 HEXIM1 和 pTEFb 从 7SK 核糖核蛋白复合物中释放，从而调节细胞内氧化还原水平。

CSB-Dependent Cyclin-Dependent Kinase 9 Degradation and RNA Polymerase II Phosphorylation during Transcription-Coupled Repair

转录偶联修复过程中 CSB 依赖的细胞周期蛋白依赖性激酶 9 降解和 RNA 聚合酶 II 磷酸化

HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb.

HEXIM1 在细胞核内的扩散受其与 7SK 和 P-TEFb 相互作用的调控。

The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations

增强型R环是高危剪接因子突变诱发骨髓增生异常综合征的统一机制

SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription

SIRT7 依赖的 CDK9 去乙酰化激活 RNA 聚合酶 II 转录